Objective：To investigate the effects and safety of azelastine nasal spray combined with desloratadine for the treatment of allergic rhinitis.Method：174 cases of allergic rhinitis in our hospital were selected from January 2012 to September 2014 and were randomly divided into research group and control group，87 cases in each group.The control group was treated with azelastine nasal spray，the research group was treated with azelastine nasal spray combined with desloratadine.The total effective rate，symptom scores before and after treatment and adverse reactions rate were compared.Result：The total effective rate of
research group was 93.1%，which was higher than 80.5% of control group，the difference was statistically significant（P<0.05）.The symptom scores of two groups before treatment had no significant difference（ P>0.05）；after treatment，the symptom scores of research group was better than control group，the difference was statistically significant（ P<0.05）.The adverse reactions rate of two groups had no significant difference（P>0.05）.Conclusion：Azelastine nasal spray combined with desloratadine in the treatment of allergic rhinitis has exact effect.It can effectively relieve clinical symptoms without serious adverse reactions.It’s worthy of clinical widely used.

2015 Vol. 12　(21):　1-4 [Abstract]（ 588 ） HTML (1 KB)  PDF  (1053 KB)  ( 219 )

Objective：To discuss the effects of IB-IIIA non-small cell lung cancer patients of EGFR overall mutation rate on lung cancer chemotherapy by ARMS analysis and detection. Method： 80 cases of lung cancer in the same medical group IAIIIA were selected in the hospital from August 2013 to August 2014， 48 patients of lung cancer in IB-IIIA after radical standard platinum-containing chemotherapy of two drugs for the condition were observed and analysed， the EGFR mutation rate of patients in gender，smoking history and pathological type were compared， the disease-free survival l period（ DFS） of postoperative chemotherapy EGFR gene mutation positive and negative was compared， the differences of drug side effects in WHO standards were compared.Result： 31 cases with lung cancer EGFR mutations in the 80 cases， the mutation rate was 38.75%；37 cases of squamous cell carcinoma，2 cases of EGFR gene mutations， the mutation rate was 5.41%；43 cases of cancer patients， 29 cases of EGFR mutations，the mutation rate was 67.44%， the difference was statistically significant（P<0.05）.IB-IIIA patients with a total of 48 cases，compared the gastrointestinal reactions of 20 cases EGFR gene mutation positive and 28 cases EGFR gene mutation negative， the difference was no statistically significant（P>0.05）；compared the DFS of two groups， the difference was statistically significant（P<0.05）.38 smokers of 20 cases with the former EGFR gene mutations， mutation rate was 52.6%，42 non-smokers of 11 cases with EGFR gene mutations， mutation rate was 26.2%， the difference was statistically significant（P<0.05）.Conclusion：The patients with non-small cell lung cancer has closely related with EGFR gene mutation and pathological type， by comparing mutation rate，the mutation rate of adenocarcinoma is higher than that of squamous cell carcinomas， the EGFR mutation status of patients can be used to predict the chemotherapy of lung cancer.

2015 Vol. 12　(21):　7-10 [Abstract]（ 578 ） HTML (1 KB)  PDF  (1044 KB)  ( 208 )

Objective：To investigate the protective effect of ginkgolide B on retinal ganglion cells after crush of intra orbital optic nerve in rats.Method：Thirty-six SD rats which were 46-day-old were randomly divided into noral control group（A group，12 rats），model control group（B group，12 rats）and Ginkgolide B group（C group，12 rats）.In each group，only the right eyes were used.No operation was carried out in normal control group，corresponding volume of NS or Ginkgolide B at 40 mg/kg was injected intraperitoneally into the rats from one week before crush until one week after crush in model control group or Ginkgolide
B group，one week and two weeks after operation，flash visual evoked potential were performed.Two weeks after operation，calculated the number of RGCs in each group.Result：one week after operation，the coefficients of LPl and APl were[（90±4）ms，（19±3）μV]，[（110±6）ms，（11±3）μV]and[（94±4）ms，（18±2）μV]respectively in noral control group，model control group and Ginkgolide B group，the differences were statistically significant among B group and A group or C group（P<0.05）.Two weeks after operation，the coefficients of LPl and APl were[（92±11）ms，（21±3）μV]，[（186±15）ms，（7±2）μV]and[（104±12）ms，（14±3）μV] respectively，the number of RGCs were（281±39），（112±20）and（228±35）respectively，the differences were statistically significant in 3 groups（P<0.05）.Conclusion：Ginkgolide B can partly inhibit the apoptosis of RGCs and promote the survival of RGCs after crush of intra orbital optic nerve.

2015 Vol. 12　(21):　13-16 [Abstract]（ 376 ） HTML (1 KB)  PDF  (2300 KB)  ( 155 )

Objective： To explore the curative effect observe of gene modified bone marrow mesenchymal stem cells transplantation on acute myocardial infarction in rats.Method： 20 SD rats of 15 day old were selected and divided into two groups，the observation ervation group（ vascular endothelial growth factor group） and control group（ DMEM group）， 10 rats in each group， thepreparation of acute myocardial infarction model， the observation group rats underwent gene modified bone marrow mesenchymal stem cells transplantation，the control group rats were injected with serum free DMEM， after one month transplantation，the cardiac function of two groups were observed. Result： The observation group and the control group LVEF rats were respectively
（73.45±9.17）% and（ 43.26±6.33）%， the observation group was significantly higher than that in the control group， the difference was statistically significant（P<0.05）；two groups of rats were found with microscope in the formation of left ventricular scar tissue，with angiogenesis and the emergence of remodeling left ventricular， compared with the control group，the observation group rats heart changed significantly； the observation group and the control group of rats with vascular density of rats were respectively（ 45.69±4.28） and（ 17.41±3.67）， the observation group was significantly higher than that in the control group， the difference was statistically significant（P<0.05）. Conclusion： Vascular endothelial growth factor gene modified bone marrow mesenchymal stem cells transplantation has good therapeutic effect on acute myocardial ischemia in rats.

2015 Vol. 12　(21):　19-21 [Abstract]（ 528 ） HTML (1 KB)  PDF  (1681 KB)  ( 182 )

Objective：To investigate the effect of hachong Shisan Wei Pill on apoptosis of hippocampal cells after ischemic brain injury.Method：After establishment of SAH model， the percentage of apoptosis and Bax/Bcl-2 protein expression level of the nerve cells were detected by the flow cytometry and Elisa . Result：Compared with the control group，the apoptosis percentage and the Bax protein expression of model group were significantly increased，and the Bcl-2 protein expression were decreased（P<0.05）.Compared with the model group，the apoptosis percentage and the Bax protein expression of Zhachong Shisan Wei Pill group were significantly decreased， and the　Bcl-2 protein expression were increased（P<0.05）.Conclusion：Zhachong Shisan Wei Pill has protective effect on hippocampal cells after cerebral ischemia by decreasing the nerve cell apoptosis，regulation of apoptosis related gene Bax/Bcl-2 expression is one of its anti-apoptosis mechanism.

2015 Vol. 12　(21):　24-26 [Abstract]（ 646 ） HTML (1 KB)  PDF  (1030 KB)  ( 267 )

Objective：To investigate the safety and therapeutic effect of early rehabilitation treatment for cerebral hemorrhage patients with non-surgical treatment in intensive care unit（ICU）.Method：Eighty-three cerebral hemorrhage patients with non-surgical treatment in our hospital from June 2012 to June 2014 were selected and randomly divided into treatment group with forty-two cases and control group with forty-one cases.The treatment group was treated with early rehabilitation measure，the control group was given conventional treatment.The recovery situation of neurological deficits and daily life ability were compared between the two groups before and after treatment.Result：After treatment，the clinical neurological deficit scores of the treatment group were significantly lower than before treatment and significantly lower than those of the control group（P<0.001）.Barthel index scores of the treatment group were significantly higher than before treatment and significantly higher than those of the control group，the differences were statistically significant（P<0.001）.In the treatment group，the basic life activities of the patients recovered rapidly，twenty-eight patients（66.67%） achieved basic self-care living after fourteen days of treatment，twenty patients（47.61%） could walk independently.Conclusion：Early rehabilitation treatment can significantly improve basic life skills of cerebral hemorrhage patients with non-surgical treatment.Intensive rehabilitation must have professional rehabilitation team，early rehabilitation treatment conducted by professional therapists is safe and effective for intensive patients.

2015 Vol. 12　(21):　31-33 [Abstract]（ 478 ） HTML (1 KB)  PDF  (1053 KB)  ( 194 )

Objective：To study the effect of Prednisone combined with vitamin B12 in the treatment of chronic cheilitis.Method：56 adult patients with chronic cheilitis were randomly divided into two groups，26 cases in the control group were given the conventional treatment，30 cases in the experimental group were given the therapy of Prednisone Acetate combined with vitamin B12.1-year follow-up was given to the two groups，the clinical effect was judged by the situation of dryness，desquamation，rahagades，hyperemia，edema and erosion of the lip.Result：The cure rate and total effective rate of the experimental group were significantly higher than those of the control group（P<0.05）.Conclusion：Treating chronic cheilitis with Prednisone combined with vitamin B12 is significantly effective，it is worth clinical applying.

2015 Vol. 12　(21):　36-38 [Abstract]（ 761 ） HTML (1 KB)  PDF  (1052 KB)  ( 228 )

Objective：To investigate the clinical value of endocrine disorders of infertility by combination therapy.Method： 110 patients with infertility of endocrine disorders in our hospital were selected as the research objects from June 2013 to June 2014，all the patients were treated by human menopausal gonadotropin， chorionic gonadotropin and crow clomiphene combined treatment， and the treatment effect was analysed. Result：110 patients were treated with 233 cycles， 203 cycles had ovulation， the ovulation rate was 87.1%（203/233）.110 patients were treated with the first cycle of 36 cases success， 74 patients were treated with the second cycle of 25 cases success， 49 patients were treated with the third cycle of 7 cases success. 68 cases were successful，the pregnancy rate was 61.8%（68/110）；6 patients occurred ovarian hyperstimulation syndrome， accounted for 5.5%（6/110）. Conclusion： Using human menopausal gonadotropin， human chorionic gonadotropin and combined medication of clomiphene citrate three drug way on endocrine disorders of patients with infertility treatment has good effect，it is conducive to the promotion of ovulation and pregnancy，has less adverse reaction， significant clinical value， so it is should be popularized and applied.

2015 Vol. 12　(21):　42-44 [Abstract]（ 570 ） HTML (1 KB)  PDF  (1042 KB)  ( 157 )

Objective：To analyze the ultrasonographic characteristics of clinical staging and advantages by transrectal ultrasound in the examination of prostate cancer，and to reflect its clinical application value.Method：55 patients were detected by GE Logie 500Pro color Doppler ultrasonic diagnostic apparatus，probe frequency 5-7.5 MHz，they were aged 58-89 years old，average 73.5 years old，digital rectal examination（ DRE） touch prostate hard or suspicious nodules，serum specific antigen（ PSA）>4 ng/mL and detected by transrectal ultrasound（ TRUS），combined with clinical staging contrasted
ultrasonographic manifestations and characteristics，and these patients were performed transrectal ultrasound guided biopsy，and surgery confirmed for prostate cancer.Result：In 55 cases，48 cases of prostate cancer were detected by rectal ultrasound，the coincidence rate was 87.3%，the ultrasound characteristics were not regular，the boundary less smooth，internal and externalgland boundary was not clear，local uplift，hypoechoic nodules or breakthrough coating，invasion of adjacent tissue or distant metastasis.7 cases were diagnosed as benign prostatic hyperplasia or nodular hyperplasia，the misdiagnosis rate was 12.7%，the sonographic features were neat shape，smooth boundary，internal and external gland boundary was clear，internal medium echo and the surrounding medium had a narrow low echo tubercle.Conclusion：Transrectal ultrasound is a higher positive detection rate of prostate cancer screening method，according to the sonographic characteristics determine the initial clinical stage，has clinical value.The image resolution is significantly better than the examination of the abdomen，and non-invasive，low cost，simple operation，easy to be accepted by patients，has important application value for clinical.

2015 Vol. 12　(21):　48-51 [Abstract]（ 740 ） HTML (1 KB)  PDF  (1135 KB)  ( 336 )

Objective：To research the effect of regular withdrawal of Compound Betamethasone in treating keloid by intralesional injection.Method：A total of 156 patients with keloid in our hospital from January 2007 to December 2014 were selected and randomly divided into two groups.There were 81 cases in the experimental group（group A） and 75 cases in the control group（group B）.Compound Betamethasone was injected into the keloid lesions of the patients in group A and the drug concentration was gradually decreased in the treatment，while the drug was withdrawn routinely in group B.The therapeutic effect and recurrence rate were compared between the two groups.Result：One month and six months after the treatment，the effect of the two groups had no statistical difference（P>0.01）.The recurrence rate of group A was lower than that of group B，the difference was statistically significant（P<0.01）.Conclusion：Regular withdrawal of Compound Betamethasone can reduce the recurrence rate in the treatment of keloid.

2015 Vol. 12　(21):　54-56 [Abstract]（ 530 ） HTML (1 KB)  PDF  (1097 KB)  ( 226 )

Objective：To discuss clinical significance of dynamic monitoring the serum bilirubin，D–dimer（DD） in patients with acute cerebral infarctio（AMI）.Method：78 patients with AMI were selected in our hospitals as AMI group，20 cases of health personn were selected from medical center for the same period as healthy group， serum bilirubin， DD level were detected by using enzyme-linked immunosorbent method ，and analyzed change of serum bilirubin， DD level of AMI patients in hospital， the acute phase and after treatment serum bilirubin， DD level.Pearson analysis method were used to analyze the relationship between them.Result：AMI group patients bilirubin，DD expression level were higher than healthy group，the difference was statistically significant（P<0.05）.AMI patients in acute phase serum bilirubin，DD expression level were the highest，the expression level at hospitalization serum bilirubin，DD findings was the second，the expression level after treatment serum bilirubin，DD expression was the lowest（P<0.05）.Pearson analysis results showed that the serum bilirubin level was positively correlated with DD level（r=0.689，P=0.689）.Conclusion：AMI patients can cause and serum bilirubin，DD expression level change， and both are positively correlated，the dynamic monitoring the expression level of disease progression and the curative effect of patient evaluation have an important reference value.

2015 Vol. 12　(21):　60-62 [Abstract]（ 631 ） HTML (1 KB)  PDF  (1222 KB)  ( 255 )

Objective：To observe the safety of transverse incision jacking method of extraperitoneal cesarean section.Method：1210 cases with caesarean section from 3810 pregnant women in our hospital from January 2011 to December 2014 were selected，1200 cases were randomly divided into the treatment group and the control group，600 cases in each group.The control group was treated with traditional intraperitoneal cesarean operation，the treatment group was treated with
transverse incision jacking method of extraperitoneal cesarean section.The intraoperative and postoperative observation index and complications between the two groups were observed and compared.Result：The total time of cut skin to birth，total operation time，postoperative transfusion time，duration of indwelling urinary catheter，and start eating time intestinal exhaust time and hospitalization time in the treatment group were significantly shorter than the control group，intraoperative blood loss was significantly less than the control group，the postoperative fever rate was significantly lower than the control group，the differences were statistically significant（P<0.05）.Conclusion：Transverse incision jacking method of extraperitoneal cesarean has faster postoperative recovery，less complications and satisfactory clinical effect，is worthy of clinical popularization and application.

2015 Vol. 12　(21):　66-69 [Abstract]（ 587 ） HTML (1 KB)  PDF  (1203 KB)  ( 148 )

The diagnosis of ECG is one of the basic skills of clinician.But now，clinician are lack of this kind of ability. ECG core theory as the theory of"secondary projection"，namely different moments of ECG integrated vector space vector ring successively through two-dimensional projection plane and one dimensional linear space form ECG theory.This article will be to the ECG vector theory in the teaching of ECG positioning for analysis，the importance of cardiac vectors in ECG education is analyzed，and how to use in the ECG teaching and strengthen the theory，for improving the teaching effectiveness of ECG.

2015 Vol. 12　(21):　72-75 [Abstract]（ 478 ） HTML (1 KB)  PDF  (1198 KB)  ( 352 )

This article discuss on how to prevent nurse patient disputes， and reduce the incidence of disputes. To analyze the causes of our department by common disputes generated， and to formulate the corresponding preventive measures， to prevent and reduce the occurrence of nurse patient disputes by enhancing the sense of responsibility and sense of service， improve service attitude， improve service quality， strengthen the professional quality training and the training of law， has important clinical significance in reducing the incidence of nurse patient disputes.

2015 Vol. 12　(21):　78-79 [Abstract]（ 596 ） HTML (1 KB)  PDF  (1025 KB)  ( 161 )

Objective：To discuss and analyze safety problems and nursing countermeasures of elderly patients undergoing transurethral resection of the prostate surgery.Method： 100 elderly patients undergoing transurethral resection of the prostate in our hospital were randomly divided into two groups， the control group was prepared in accordance with the conventional operation，observation group adopted comprehensive prevention measures，the change of perioperative body temperature， blood pressure，heart rate of the two groups were observed， and at the same time，chills， bladder spasm， sacrococcygeal pressure red， blisters and other postoperative complications of the two groups were compared，bladder irrigation fluid volume， washing time， amount of bleeding of the two groups were compared.Result：The operation temperature，blood pressure，heart rate and other indicators at
different time points in the experimental group showed no obvious change（P>0.05）；compared with pre anesthesia， temperature in control group in operation 30 min after and at the end were statistically significant（P<0.05）.Patients in the experimental group postoperative shivering， bladder spasm， sacrococcygeal pressure red，blisters and other complications and postoperative bladder irrigation fluid volume， washing time， amount of bleeding were significantly lower than those of the control group， with statistical differences（P<0.05）.Conclusion：The security factors of urethral prostate electric cut operation in old patients has skin injury，neural injury，cycle，and respiratory disease，for old patients body each organ function gradually recession，immunity declined，prevention sex take measures for protection measures，can reduced old patients surgery risk， avoid burst heart， and vascular disease accident situation of occurred，worth widely application in surgery department.

2015 Vol. 12　(21):　82-84 [Abstract]（ 612 ） HTML (1 KB)  PDF  (1159 KB)  ( 234 )

Objective：To investigate the effect of psychological intervention on post-traumatic stress disorder（ PTSD）of emergency deep burn patients.Method：126 emergency deep burn wounds patients in our hospital were selected as research objects， they were randomly divided into two groups， the observation group（64 cases） received routine nursing combined with mental intervention， control the group（62 cases） was given routine nursing， the incidence and degree of PTSD were compared.Result：The PTSD incidence of the observation group was low to 29.69%， which was significantly lower than the control group（51.61%），there was a statistically significant difference between the two groups（P<0.05），the PTSD score（ re experience，avoidance， numbness，alertness heighten and total PTSD） of observation group were significantly lower than control group，SAS score and SDS score were significantly lower than control group，the acceptance of disability score and psychological resilience score were significantly higher than control group， the difference between groups was significant（P<0.05）.Conclusion： The psychological intervention is helpful to reducing PTSD rate of emergency deep burn patients，improving PTSD degree，anxiety and depression，also assisting in early disability acceptance， improving self confidence to overcome disease.

2015 Vol. 12　(21):　88-90 [Abstract]（ 482 ） HTML (1 KB)  PDF  (1160 KB)  ( 158 )

Objective： To investigate the influence of different nursing interventions on negative emotions of the patients with sudden deafness and tinnitus. Method： The objects of this study were 80 patients with sudden deafness and tinnitus in the Otolaryngological Department of our hospital. Among these 80 patients， 40 patients who accepted routine care were considered as the control group， while another 40 patients who were given integrated care on the basis of routine care were regarded as the observation group. Pittsburgh Sleep Quality Index， Hamilton Anxiety Scale score and Self-rating Depression Scale score of the two groups before and after treatment were compared. Result： Before nursing， the evaluation of different observation targets of the two groups was similar， so the difference was not statistically significant（ P>0.05）. After nursing， the evaluation of different observation targets of the observation group were better than those of the control group， and the differences were statistically significant（ P<0.05）. Conclusion： Certain nursing interventions can improve the sleep quality and psychological state of the patients with sudden deafness and tinnitus， and the improved effect of integrated nursing is better than the usual nursing.

2015 Vol. 12　(21):　94-96 [Abstract]（ 588 ） HTML (1 KB)  PDF  (1173 KB)  ( 340 )

Objective：To discuss correlation of human papilloma virus（ HPV） subtypes distribution characteristics and age in Huizhou region.Method：2576 women of cervical secretions exfoliated cells were selected from January 2013 to December 2014 in our hospital outpatient service and examination， on the basis of age， all women was divided into young group（ 20-29 years old），mid-young group（ 30-39 years old）， middle age group（ 40-49 years old）， old age group（ >49 years old）， HPV diversion hybridization rapid genotyping technology was used to detect HPV subtype， analysed all the subjects of HPV subtypes distribution characteristics and its relationship with age.Result： In Huizhou region，2576 cases of specimens after HPV gene examination and classification diagnostic screening out of 412 cases were positive for HPV infection， total infection positive rate was 15.99%，and HPV subtypes 52 infection rate was the highest（2.45%），HPV subtype 2 infection rate was the lowest（0.08%）， the former was significantly higher than the latter，the difference was statistically significant（X²=7.72，P<0.01）.High-risk type HPV infection rate was 14.01%，low-risk HPV infection rate was 1.98%，the former was significantly higher than the latter（X²=7.13，P<0.01）.Young group of HPV infection percentage was 29.38%， mid-young group of HPV infection percentage was 57.77%， middle age group of HPV infection percentage was 9.45%， old age group of HPV infection percentage was 3.40%， mid-young group>young group>middle age group>old age group（P<0.05）.Conclusion：Risk HPV infection in Huizhou has significant heterogeneity subtypes and age distribution， to guide the HPV vaccine research and early prevention and treatment of HPV infection has important clinical value.

2015 Vol. 12　(21):　102-104 [Abstract]（ 525 ） HTML (1 KB)  PDF  (1187 KB)  ( 371 )

Text information extraction became a novel mechanism for knowledge mining from texts in Traditional Chinese Medicine（ TCM） domain in recent years.We constructed an ontology-based text information extraction system for TCM domain.It can extract semantic relations from TCM texts，and support users to browse，analyze，and annotate these relations. This system can facilitate TCM experts to acquire knowledge from TCM documents， and further refine TCM domain ontologies.

2015 Vol. 12　(21):　108-110 [Abstract]（ 464 ） HTML (1 KB)  PDF  (2266 KB)  ( 250 )

Objective：To explore the constructive mode of skill training base for minimally-invasive surgery in community hospitals of Guangzhou.Method：Skill training base for minimally invasive surgery was established by setting up management institutions，constructing training base and standardizing training disciplines.Result：The trainees could better master the application of minimally invasive surgery and obtain the official endoscopic operation certificate.Conclusion：Standard training model creates positive effects on professional training for minimally invasive surgery in community hospitals.

2015 Vol. 12　(21):　113-115 [Abstract]（ 405 ） HTML (1 KB)  PDF  (1178 KB)  ( 235 )

Objective：To approach the influence of children vaccination by individualized health education in patriarch.Method： 500 patriarches of 0-3 age children for suitable vaccination in our jurisdiction were selected from May 2014 to December 2014 and were divided into two groups，control group of 200 cases and intervention group of 300 cases. The cognitive level score of patriarch vaccination， qualification rate of I kind of vaccination and vaccination work satisfaction of two groups were detected.Result：The intervention group of cognitive level score patriarch vaccination，the qualification rate of I kind of vaccination and vaccination work satisfaction were better than that control group，the differences were statistically significance（P<0.05）.Conclusion： The cognitive level and satisfaction of children vaccination by Individualized health education in patriarch are improved，the qualification rate of I kind of vaccination are improved，which is to be used.

2015 Vol. 12　(21):　118-121 [Abstract]（ 555 ） HTML (1 KB)  PDF  (1323 KB)  ( 232 )

Objective：To study the effect of internal operative fixation with memory alloy on acetabular fractures patients. Method： 20 cases of acetabular fracture patients in our hospital from 2013 to 2014 were selected as the research objects， 10 patients in the surgery group were given open reduction and internal memory alloy fixation treatment，10 patients in the nonsurgical group were given traction conservative treatment.All patients were followed up by one year，they were given reexamination 3 and 8 months after the surgery.All patients’ hip joint function were graded before treatment and 8 months after the surgery. Result：3 months after surgery，walking function of the surgery group was better than that of the non-surgical group（P<0.05）.8 months after surgery，hip function scores of the surgery group was significantly higher than that of the non-surgical group（P<0.05）.All patients were followed up by one year，there were no occurrence of adverse events，muscle strength of the surgery group was better than that of the non-surgical group（P<0.05）.Conclusion：Using internal operative fixation with memory alloy on acetabular fractures patients can get better results for the recovery of hip function.

2015 Vol. 12　(21):　126-127 [Abstract]（ 519 ） HTML (1 KB)  PDF  (1102 KB)  ( 274 )

Objective： To investigate the influence of median cubital vein and dorsal venous puncture point on renal artery magnetic resonance imaging.Method：32 patients on renal artery magnetic resonance imaging treated from June 2013 to November 2014 in our hospital were selected and randomly divided into two groups，respectively chosen median cubital vein and dorsal vein as the puncture point to proceed renal artery magnetic resonance imaging，the Test Bolus was used to monitor two groups of renal artery imaging peak time，Cor Cemra FT sequence was chosen for renal artery imaging to evaluate the vascular signal strength of the two sets of image，signal to noise ratio（SNR） and image contrast to noise ratio（CNR）and reconstruction of vascular score.Result：All of the 32 cases completed the inspection，two groups of peak time delay，respectively：median cubital vein point was（24±3.4）s，the dorsal vein of foot point was（45±5.1）s，the differences were significant（P<0.05）.There were totally 67 renal arteries imaging，12 cases of renal artery were normal，21 cases were stenosis，and 1 artery was totally occlusion.Two groups of signal intensity at the renal arteries openings were（751.25±14.2），（738.98±31.3）；SNR were（73.11±4.5），（71.96±9.5）；CNR were（41.74±9.3），（40.24±12.6），there was no statistical difference（P>0.05）.Reconstruction of renal artery both reached the requirement of diagnosis，with no difference between the two groups.Conclusion：When the median cubital vein upper limb venous puncture failure，dorsal vein can be optional to meet the clinical demand at renal artery magnetic resonance imaging.

2015 Vol. 12　(21):　132-134 [Abstract]（ 498 ） HTML (1 KB)  PDF  (1242 KB)  ( 212 )

Objective： To study the mechanical ventilation in critically ill in the treatment of severe hand， foot and mouth disease clinical application and therapeutic effect. Method：A total of 433 cases of hand， foot and mouth disease were selected from September 2012 to December 2013 in our hospital. On the basis of routine treatment， according to the given mechanical ventilation patients adjuvant therapy， the detection of patients with all the vital signs of change， statistical patients after treatment.Result： The average of white blood cell count in patients was（ 14.1 ± 6.9） × 109 / L； the average blood glucose was（ 8.4 ± 5.3） mmol / L； PaCO2 average was（ 28.9 ± 8.3） mm Hg； CRP average was（ 6.89 ± 10.1） mg / L； the rate of effect was 86.8%；the average of ventilator time was（6.5 ± 2.1） h； no change in the patient's condition or even deteriorated were 57 cases （13.2%）. Conclusion： Mechanical ventilation is an effective auxiliary treatment， this treatment is worth wide application in the clinical practice and popularization.

2015 Vol. 12　(21):　138-139 [Abstract]（ 492 ） HTML (1 KB)  PDF  (1102 KB)  ( 215 )

Objective：To analyze the clinical effect of laparoscopic resection of anal sphincter（ISR） in the anus preserving operation（SSO） of ultra-low rectal cancer.Method：80 patients were selected from our hospital admissions of ultralow SSO as the research objection which were randomly divided into two groups，40 cases in each.In control group underwent the implementation of open processing，and study group underwent laparoscopic ISR treatment，the operative time，amount of bleeding，hospitalization time，complications were observed and recorded.Result：The operative time，intraoperative bleeding，hospitalization time and complication rate of the study group were significantly better than those of the control group，the differences were statistical significance（P<0.05）.Conclusion：The laparoscopic ISR treatment for ultra-low rectal cancer patients can achieve good results，less time-consuming，less bleeding，less hospitalization time and the incidence of complications is low，it is worth to learn from.

2015 Vol. 12　(21):　142-144 [Abstract]（ 573 ） HTML (1 KB)  PDF  (1254 KB)  ( 203 )

Objective：To evaluate the clinical efficacy of Insulin glargine combined with Repaglinide in the treatment of elderly type 2 diabetic nephropathy.Method：60 elderly patients with type 2 diabetes mellitus and early nephropathy admitted to our hospital from January 2012 to November 2014 were selected，and they were divided into the experimental group and the control group according to the random number table method，30 cases in each group.The experimental group was given Insulin glargine combined with Repaglinide for treatment，the control group was given Novolin 30R for treatment.The clinical curative effect，the changes of blood glucose and kidney function before and after treatment，incidence of hypoglycemic events between the two groups were observed and compared.Result：After 12 weeks of treatment，the total effective rate of the experimental group was 93.3%，which was significantly higher than 73.3% of the control group，the difference was statistically significant（ X²=4.3200，P=0.0377）.The fasting blood-glucose，postprandial 2 h blood glucose glycosylated hemoglobin level of the experimental group after treatment were significantly better than those of the control group，the usea nitrogen，serum creatinine，
glomerular filtration rate and urinary albumin excretion rate were significantly lower than those of the control group，the incidence of hypoglycemic events was significantly lower than the control group，the differences were statistically significant（P<0.05）.Conclusion：The clinical effect of Insulin glargine combined with Repaglinide in the treatment of elderly type 2 diabetic nephropathy is good，can effectively reduce the occurrence of complications，reduce the incidence of hypoglycemia，is worthy of clinical popularization and application.

2015 Vol. 12　(21):　147-149 [Abstract]（ 575 ） HTML (1 KB)  PDF  (1279 KB)  ( 206 )

Objective：To explore the clinical curative effect of oral rehabilitation after treatment for elderly patients.Method：80 patients with elderly oral disease in our department from June 2012 to November 2013 were selected as research objects.After oral examination，they were chosen corresponding therapy according to condition，the clinical effects after treatment were investigated.Result：All patients with a follow-up of 1 year after the discovery，in 47 male patients，19 cases were cured，15 cases were markedly effective，10 cases were effective，the clinical total effective rate was 93.6%.In 33 female patients，5 cases were cured，10 cases were markedly effective，15 cases were effective，the clinical total effective rate was 90.9%.Conclusion：The effect of oral rehabilitation for elderly patients is obvious，is worth using for reference.

2015 Vol. 12　(21):　151-152 [Abstract]（ 652 ） HTML (1 KB)  PDF  (1124 KB)  ( 170 )