Objective：To investigate the relationship between the rs10244837， rs7794745， rs10500171 SNPs of the CNTNAP2 gene and autism in Han Chinese.Method：The rs10244837， rs7794745， rs10500171 SNPs of CNTNAP2 was genotyped by PCR-RFLP in individuals with autism and normal subjects. An association study was performed used the data of genotyping.Result：The frequencies of the genotypes rs10244837， rs7794745， rs10500171 SNPs were in Hardy-Weinberg equilibrium（ HWE）（ P>0.05）.There were no significant differences in allele frequency and
haplotypes frequencies distribution of the CNTNAP2 gene between the autisms group and normal control group（ P>0.05）. Conclusion：The SNPs rs10244837， rs7794745， rs10500171 of CNTNAP2 gene were not association with autism in Han Chinese.

2015 Vol. 12　(03):　1-3 [Abstract]（ 683 ） HTML (1 KB)  PDF  (665 KB)  ( 202 )

Objective：To investigate the mental health states of medical staff in Hechuan district of Chongqing. Method：Totally 570 medical staff were enrolled for Symptom Checklist 90（ SCL-90） test. The subjects with SCL-90 score >160 were considered as under abnormal psychological health. The total score of SCL-90， as well as the scores of somatization， obsession，sensitivity to personal relationship， depression， anxiety， hostility， dread， paranoid-ideation and psychotics， was computed and compared with statistic methods.Result：The results showed that the rate of medical staff was 18.95%（ 108/570）， while for the clinical nurses， clinicians， medical staff in the district units and in town units， the rates of abnormal health were estimated to be 23.20%（ 58/250）， 15.63%（ 50/320）， 25.60%（ 75/293） and 11.91%（33/277） respectively. The scores of multiple factors were obviously different between the medical staff in this district and the national norm. The SCL-90 scores of the medical staff in the district units showed a marked higher than those in town units（P<0.01）. The obsession， depression， anxiety， hostility and the total scores of clinical nurses were obviously higher than those of clinicians（P<0.01），and psychotics scores showed a difference between the two groups（P<0.05），while there were no significant differences in somatization， sensitivity to personal relationship，dread and paranoidideation scores（P>0.05）.Conclusion：The mental health status of the medical staff were in a poor state in the district. The medical staff in the district units had more psychological problems than those in the town units； clinical nurses were in worse mental health states compared to clinicians.

2015 Vol. 12　(03):　7-9 [Abstract]（ 488 ） HTML (1 KB)  PDF  (665 KB)  ( 227 )

Objective： To investigate the value of multi-slice CT imaging in the diagnosis and preoperative bladder cancer before staging.Method： 83 cases of preoperative staging of bladder cancer diagnosis treatment in our hospital from May 2008 to June 2012 were retrospective analyzed， all patients were two-dimensional ultrasound scanning and multi-slice CT imaging scan（ referred to as spiral CT ） detected by two experienced physicians read the piece doubleblind
method and preoperative staging of bladder cancer T， statistical analysis of the two detection methods in detection of bladder cancer foci， staging situation.Result：83 cases of bladder cancer， spiral CT detection of various parts of the patients with bladder cancer foci were higher than those detected in the number of two-dimensional ultrasound detection，the former total number of detected foci were significantly higher than the latter， the difference were statistically significant（P<0.05）； spiral CT detection of bladder cancer before surgery specificity T staging of 96.38%， a sensitivity of 85.27%，accuracy was 93.34%， a specificity of two-dimensional ultrasound detection of bladder cancer before surgery T staging was 88.54%， the sensitivity was 79.62%， accuracy was 85.81%， significantly higher than the former to the latter， the difference were statistically significant（ P<0.05）. Conclusion： Spiral CT imaging can be used as an effective method to detect bladder cancer diagnosis， which can effectively improve the accuracy of preoperative T staging of bladder cancer before， helping physicians develop appropriate treatment programs worthy of further promotion.

2015 Vol. 12　(03):　13-15 [Abstract]（ 584 ） HTML (1 KB)  PDF  (665 KB)  ( 202 )

Objective：To investigate the activation of astrocytes in spinal cord of spinal nerve selective ligation（SNL） rats’ mirror-image pain model. Method：The experimental group（ n=20） was SNL mirror-image pain model group， the control group（ n=20） was SNL model group. Every group was took the L4-L5 spinal cord to make paraffin slices. Labeled the expression of glial fibrillary acidic protein（ GFAP） by immunofluorescence method.Result：The positive
cells GFAP marked were increased in the number and the mean fluorescence intensity in the experimental groups’spinal dorsal horn of non-surgical side which had no statistical significance（ P>0.05） compared with the surgical side， but had statistical significance（ P<0.05） compared with the non-surgical side of the control group. Conclusion：In the neuropathic mirror-image pain， astrocytes were activated and involved the formation and maintenance of mirror pain in the mirror side of the spinal cord.

2015 Vol. 12　(03):　18-20 [Abstract]（ 522 ） HTML (1 KB)  PDF  (681 KB)  ( 217 )

Objective：To establish a simple， reliable model of middle cerebral artery occlusion-reperfusion model in wistar rats.Method：On the basis of the method of Longa， 60 male wistar rats were randomly divided into two groups， 30 rats in each group. In the experimental group， the proximal part of the right common carotid artery（ CCA） was ligated， the distal part of the CCA was clipped， then a small cut was made in CCA， thread was put into the internal carotid artery（ ICA） through the cut of CCA to block the blood flow in the right of middle cerebral artery. One hour later，the thread was draw out under the condition of anesthetization， then the distal part of right CCA was ligated. In the control group， the proximal and distal part of the right common carotid artery（ CCA） was ligated without putting thread into ICA. After operation， brain tissue was taken out to undergo TTC staining， and neurological deficit sign scores were performed.
Result：The successful rate of modified MCAO/R model was 82.75%， the average time of operation was（ 20.4±5.3） min. In the experimental group， the right eye fission was smaller， the left extremities were paralyzed， and animals turn right while walking. The neurological deficit sign score was 3-4， the brain tissue supplied by right middle cerebral artery was pale under TTC staining， the areas of infarction was stable and the average area of infarction was about（ 34.62±5.32）%. There was no any neurological deficit in control group， and no positive results under TTC staining.Conclusion：Modified model of wistar rat ischemia-reperfusion injury has been established.

2015 Vol. 12　(03):　24-27 [Abstract]（ 665 ） HTML (1 KB)  PDF  (685 KB)  ( 318 )

Objective：To observe the charateristics of pathological myopia image ， explore the macular morphology change.Method：67 cases（ 90 eyes） with pathologic myopia maculopathy were examined by optical coherence tomography（ OCT） ，fundus fluorescein angiography（ FFA）. Indocyanine green angiography（ ICGA） was done if need be.Result：The fundus changes of the pathologic myopia were divided into 8 types：（1）pathologic myopia with lacquer
cracks，18 eyes in the 12 cases（20%）；（2）pathologic myopia with macular epiretinal membrane，9 eyes in the 6 cases（10%）；（3）pathologic myopia with fuchs spots，8 eyes in the 5 cases（8.9%）；（4）pathologic myopia with macular hemorrhage，28 eyes in the 22 cases（31.1%）；（5）pathologic myopia with macular atrophy，9 eyes in the 14 cases（15.6%）；（6）pathologic myopia with macular retinoschisis，6 eyes in the 6 cases（6.7%）；（7）pathologic myopia with macular hole，4 eyes in the 4 cases（4.4%）；（8）pathologic myopia with retina detachment，3 eyes in the 3 cases（2.7%）.Conclusion：OCT can observe microstructure of the macular morphology， but FFA and ICGA is quite useful in identifying the nature of disease，evaluating the progonosis and guiding the treatment.

2015 Vol. 12　(03):　31-33 [Abstract]（ 757 ） HTML (1 KB)  PDF  (687 KB)  ( 374 )

Objective： To investigate options and clinical efficacy of phimosis， prepuce surgical using traditional and new circumcision act.Method： The clinical data of 3000 patients were retrospectively analyzed， they used the traditional method（ n=500） and a new ring-cut method（ n=2500） treatment of phimosis or prepuce in our hospital. Then the two methods including the operative time， blood loss， postoperative pain and discomfort time， the surgeon and patient
satisfaction with surgery， postoperative complications， healing time， the foreskin edema， the patient satisfaction with postoperative appearance degrees were compared. Result： New circumcision spended short time， accompanied by less bleeding. There were 25 cases of postoperative wound bleeding（ 1%）， but had no knot. Patients didn’t need dressing and stitches and could take a bath. 50 cases happened adhesions and incarcerated of Foreskin and glans after surgery. This surgery was adapted to child. Traditional circumcision wasted of time and was easy bleeding. There were 10 cases of postoperative wound hematoma（ 2%）， residual bleeding knot. Edges of the incision was irregular. Patients needed dressing and stitches and could not take a bath. Adhesions and incarcerated of Foreskin and glans didn’t happen after surgery. This surgery was adapted to adult. Conclusion： The traditional circumcision is adapted to adult and the new circumcision is adapted to child for phimosis and prepuce. Surgical options should also be considered according to the different surgical techniques， surgical proficiency， the patient’s request and so on.

2015 Vol. 12　(03):　37-39 [Abstract]（ 444 ） HTML (1 KB)  PDF  (664 KB)  ( 336 )

Objective：To discuss the effect of incubation period line block anesthesia intra-spinal canal labor analgesia on pregnant women pregnancy outcome and neonatal prognosis.Method：174 pregnant women with incubation period line block anesthesia intra-spinal canal labor analgesia were selected from January 2013 to March 2014 in our hospital， according to the random distribution， all patients were divided into latent group and the control group. Two groups of pregnant women were given the conventional block anesthesia labor analgesia intra-spinal canal treatment， the control group of pregnant women in the palace mouth up higher than 3 cm given implementation of the latent group of pregnant women in the palace mouth expansion when 1-2 cm to implementation. The pain of pregnant woman were assessed by （VAS） in their palace mouth began to expand， labor time， pain status， delivery outcome and perinatal outcome of all pregnant women were statistical analyzed.Result：The latent group of pregnant women first and second maternal labor time were significantly shorter than the control group， the palace mouth expansion within 60 min each time VAS score was significantly lower than the control group， the difference were statistically significant（ P<0.05）； The latent group of pregnant women delivery outcome was significantly better than the control group（ P<0.05）； The latent group of pregnant women perinatal outcome was significantly better than the control group（ P<0.05）.Conclusion：Incubation period line block anesthesia intra-spinal canal labor analgesia method can effectively reduce maternal labor time， quickly relieve pain， maternal implement labor epidural and pregnancy outcomes of pregnant women and perinatal outcome， is helpful to improve the level of neonatal prognosis， it’s worth for further clinical promotion.

2015 Vol. 12　(03):　42-44 [Abstract]（ 542 ） HTML (1 KB)  PDF  (665 KB)  ( 198 )

Objective：To evaluate efficacy of the stellate ganglion block and manipulation on treating sympathetic cervical spondylosis.Method：80 cases were randomly divided into treatment group（ n=40） and control group（ n=40）.The manipulation treatment was used on treatment group； meanwhile the stellate ganglion block on control group. The treatment was administered in 20 days in a row . The clinical data and vertebral basilar artery blood flow changes were collected from two groups of patients.Result：There was no significance in treatment efficacy difference between two groups（ P>0.05）. The difference is statistically significant between the two groups in blood flow velocity before and after treatment（ P<0.05）. Conclusion：The manipulation on treating sympathetic cervical spondylosis is a perfect treatment，can be used individually to treat sympathetic type of cervical spondylosis.

2015 Vol. 12　(03):　47-49 [Abstract]（ 530 ） HTML (1 KB)  PDF   (0 KB)  ( 98 )

Objective：To explore the best time point and the distribution range of the imaging of hepatic portalvein using 256-slice spiral CT perfusion technique，to find the best way in the hepatic portal vein scanning.Method：30 patients underwent upper abdominal scanning by 256-slice Spiral CT in the first. Done the continuous dynamic scanning delaying 5 s after injection of contrast agents，then observe the whole process of the hepatic portal imaging to get the best distribution range of exposure time. According to this distribution range to set exposure points， then 57 patients underwent upper abdominal scanning. Interval scanning were done delaying 25 s after injection of contrast agents， and the interval of exposure time was 5 s， then taken four times exposures， the time points were 25， 30， 35， 40 s. Elected the best phase from the four groups of hepatic portal vein imaging to reconstruct CTV. The CT value of hepatic， liver and calculated D-value to assess the quality of images were measured. the correlation between the best time point distribution of portal vein and heart rate， weight， height of subjects were analyzed.Result： Best images could be obtained in 95% patients using multitemporal timing scanning delaying 25-40 s after injecting of contrast agents. This result had correlation with patients’heart heart rate（ P<0.05），but had no correlation with patients’ height and weight（ P>0.05）.Conclusion：Multitemporal timing scanning using 256-slice Spiral CT was another reliable method of hepatic portal vein imaging.

2015 Vol. 12　(03):　53-56 [Abstract]（ 639 ） HTML (1 KB)  PDF  (719 KB)  ( 201 )

Objective：To observe the clinical effect of continuous curvilinear capsulorhexis（ CCC） smallincision cataract surgery.Method：Contract patients who were treated in our hospital from January 2013 to June 2014 were retrospectively analyzed. Patients were evenly divided into the control group and the observation group. Coaxial phacoemulsification was performed in the control group， while CCC small-incision treatment was perform in the observation group. Clinical effects were observed. Result：The most common postoperative complication was corneal edema. The incidence of complications in the observations was significantly smaller than that of the control group （P<0.05）. No statistical significant difference of postoperative and 3-month postoperative corrected visual acuity（CVA）
between the two groups（P>0.05）.Conclusion：When treated with CCC small-incision cataract surgery， the incidence of complications was smaller yet the ultrasound time was longer. Therefore， surgical modes may be selected according to specific clinical conditions.

2015 Vol. 12　(03):　60-62 [Abstract]（ 526 ） HTML (1 KB)  PDF  (664 KB)  ( 134 )

Objective：To explore the influence on the quality of life for the patients with gastric cancer by chemotherapy combine with concurrent radiotherapy.Method：116 patients with gastric cancer were randomly divided into observation group（n=58） and control group（n=58）. The control group was treated by chemotherapy， on the basis of the control group， the observation group was treated by concurrent radiotherapy. The body weight changes， appetite change， the scores of KPS， sleep quality， survival rate for 1 year， 2 year， 3 year were compared for the two groups. Result：The scores of KPS posttreatment for the observation group were higher than the control group（ P<0.05）. There was no significant difference on the scores of KPS between prior treatment and posttreatment for the observation group （P>0.05）. The scores of KPS posttreatment for the control group were lower than prior treatment（P<0.05）. The total effective rate of the body weight changes， appetite change for the observation group were higher than the control group （P<0.05）. The sleep quality for the observation group were better than the control group（P<0.05）. The survival rate for 1， 2， 3 year for the observation group were higher than the control group（ P<0.05）. Conclusion：It can improve the quality of life for the patients with gastric cancer by chemotherapy combine with concurrent radiotherapy， the patients has good appetite， low change of body weight， sleep quality is good， it has high survival rate for 1 year， 2 year， 3 year. It is worthy of clinical promotion.

2015 Vol. 12　(03):　66-68 [Abstract]（ 458 ） HTML (1 KB)  PDF  (666 KB)  ( 286 )

Objective：To understand the situation of cervical cancer prevention knowledge and the demand of screening in Jiangsu province to make the health education work more targeted in the future.Method：One to one survey of cervical cancer prevention knowledge and screening requirements for the voluntary participation of women were conducted in 11 project sites（ 3 cities and 8 counties） from September 2012 to February 2013.Result：The 1155 full effectivequestionnaires were obtained by investigating a total of 1260 women， 303 cases of which were from area 1， not the free cervical cancer screening project sites ， 852 cases of which from area 2， the project site. The proportion of the women in area 2， who get cervical cancer prevention knowledge by "books / journals" and "publicity materials / poster book"， is higher than that of women in area 1 and the difference was statistically significant（ P<0.05）.The awareness rate of cervical cancer prevention knowledge in area 2 was higher than area 1 except cervical lesions and the difference was statistically significant（ P<0.05）. 92.21% of respondents（ 1065） were willing to accept the health examination of cervical cancer，45.63%（ 527） wanted the government to pay the full cost of inspection， and 74.11%（ 856） were willing to take screening every year. Women in area 2 are preferred to choose the family planning services for screening， while the women in area 1 choose the medical institutions.Conclusion：The knowledge of cervical cancer prevention to the local women， but it is necessary to strengthen the related health education by changing the traditional way of health education， strengthening the local family planning services construction to ensure the sustainability of screening.

2015 Vol. 12　(03):　77-80 [Abstract]（ 592 ） HTML (1 KB)  PDF  (685 KB)  ( 151 )

Objective：To explore the methods of active application of video feedback methods in medical education and experience.Method： 42 undergraduate students of grade 2011 full-time of clinical medicine were collected as the object of study，the research object according to all recent examination results from high to low ranking， will score two adjacent subjects were matched into 1 pairs， a total of 21 pairs， then each of 2 individuals were randomly assigned to the experimental group and control group. Among them，the traditional pen and paper records were used by the control  group， video feedback teaching method were used by the experimental group， VCD and the teaching of cardiopulmonary resuscitation teaching content were used， teaching 2 weeks， 2 class once a week， 2 weeks later，the teaching differences between the two groups according to the two groups of subjects skill operation assessment results and satisfaction degree on
the educational methods and effective rate were judged.Result：The control group was lower than the experimental group in the examination scores.In the interest of learning， satisfaction， serious degree of efficiency， the control group were lower than those in the experimental group， the differences were statistically significant（P<0.05）.Conclusion： Video feedback teaching in medical teaching on students' learning can improve positive effect of the interest， satisfaction， serious degree and students’ assessment scores.It is worthy to be popularized and applied in medical teaching.

2015 Vol. 12　(03):　84-86 [Abstract]（ 557 ） HTML (1 KB)  PDF  (664 KB)  ( 128 )

Objective： To investigate the effect of targeted nursing for children with severe pneumonia. Method：158 cases of children with severe pneumonia were admitted to our hospital from April 2013 to January 2014 period， were randomly divided into two groups， the control group of 78 cases，were treated routine care measures，the observe group of 80 cases， were treated targeted treatments.The efficacy of two groups patients， the incidence of complications and the care satisfaction scores were analysed and compared.Result：The incidence of complications of the observation group（6.3%） was significantly lower than the control group（19.2%），the difference was statistically significant（P<0.05）.The cure rate of the observation group was also significantly higher than the control group，the difference was statistically significant（P<0.05）.There was no significant differences of SAS psychological anxiety scores of the two group.The nurses attitude， responsibility， business proficiency and satisfaction of the observation group of were higher than the control group，the differences were statistically significant（P<0.05）.Conclusion：For children with severe pneumonia， on the basis of scientific and effective therapy， targeted care， not only can significantly reduce
the mortality of patients， but also can shorten the patient hospitalization time， play speed up the recovery process and effectively enhance the therapeutic effect of purpose ， and is conducive to enhance the quality of life of patients and patient satisfaction with hospital care， is worthy of further promotion.

2015 Vol. 12　(03):　90-92 [Abstract]（ 509 ） HTML (1 KB)  PDF  (665 KB)  ( 364 )

As the economy continues to develop， more and more advanced medical equipment， increasing the size of the hospital， people pay more attention to the quality of service in the course of medical treatment therapy，contradictions and frictions therefore call communication problems arising due to the gradual sharp. This process is called impact nurse-patient relationship means adequate communication between nurses and patients generated. This is not only convey information more emotional communication and the exchange of ideas. This paper analyzes under medical care and nurse-patient communication problems in today’s situation， after parsing through the issue of proposed countermeasures.

2015 Vol. 12　(03):　97-99 [Abstract]（ 455 ） HTML (1 KB)  PDF  (651 KB)  ( 194 )

Objective：To explore the curative effect of Qingfei Zhike pills with acupoint application on cough variant asthma. Method：120 cases of cough variant asthma patients were selected from January 2013 to Semptember 2014 and were randomly divided into two groups，60 cases in each group.The treatment group（TP） which were treated by Qingfei Zhike pills combined with acupoint application method and the control group（CP） which were treated by a Chinese patent drug called the capsule of Feilike. One course contained 10 days，the data analyzed statistically after the two groups were being treated for 2 courses. Result： The TP total curative effect and the main symptom scores， LCQ evaluation score and each index score，and small airway ventilation condition were better than that in the CP. There was a significant differences between the two group（P<0.05）. Two groups of patients with peripheral blood eosinophilia granulocyte count were improved.Conclusion：Qingfei Zhike pills combined with acupoint application has a better curative effect in treating cough variant asthma.

2015 Vol. 12　(03):　103-107 [Abstract]（ 532 ） HTML (1 KB)  PDF  (723 KB)  ( 271 )

Objective：To analysis the clinical application of the outer ring aperture approach of lower abdominal incision in the treatment of inguinal hernia in children efficacy. Method：82 cases of inguinal hernia in children were selected and divided into the study group and contrast group， 41 cases in each group. The study group patients were treated by the outer ring aperture approach of lower abdominal small incision， the contrast group were treated by the traditional operation method. The two groups of patients with treatment effect， complications and recurrence rate and satisfaction were compared. Result：The study group had 39 cases of effective and the effective rate was 95.1%， significantly higher than the contrast group’s 78% of 32 cases， the difference was statistically significant（P<0.05）； the study group had complications of scrotal edema were 2 cases，the control group of 3 cases scrotal edema，2 cases hematoma，and 1 case incision infection， the difference was statistically significant（P<0.05）；after 2 monthes， the study group of recurrence was 1 case of 2.4%， and contrast group patients were 4 cases of 9.8%； the satisfaction of the study group was higher than the contrast group ，the difference was statistically significant（ P<0.05）. Conclusion：The clinical effect of lower abdominal small incision into the path of external ring of treatment of inguinal hernia in children is significantly，it can
significantly improve the clinical effect and patients’ satisfaction.

2015 Vol. 12　(03):　115-117 [Abstract]（ 401 ） HTML (1 KB)  PDF  (663 KB)  ( 189 )

Objective： To explore the application of paraspinal muscle gap approach for the thoracolumbar fracture patients. Method： 40 patients with thoracolumbar facture were chosen and divided into two groups， the experimental group and the control group，20 cases in each group. The patients in control group were given the traditional posterior median approach treatment. The patients in the experimental group were given paraspinal muscle gap approach treatment. Then， the operation results were compared between the two groups. Result： The operation effect of thoracolumbar facture in experimental group was better than the control group. Conclusion： Paraspinal muscle gap approach has a remarkable value for the patients with thoracolumbar facture. It should be applied and spread in the hospitals of different levels.

2015 Vol. 12　(03):　121-123 [Abstract]（ 475 ） HTML (1 KB)  PDF  (663 KB)  ( 175 )

Objective： To explore and analyze the integration of electroencephalogram（ EEG） amplitude， CDI，MRI in the diagnosis of premature infant brain injury research， aiming at a premature infant brain injury to provide reliable clinical diagnosis.Method：120 premature infants treated in our hospital of pediatrics from August 2012 to August 2012 were selected， they were all tested by EEG， CDI，and MRI， and the test results were recorded.Result：the amplitude of integration of EEG examination results： this group of premature infants with 48 cases formed discontinuous low voltage or pathological type graphics， positive rate was 40.00%（ 48/120）， and failed to detect the mature CY. CDI examination results： this group of 33 cases of patients with intracranial found positive lesions， positive rate was 27.50%（ 33/120），including 15 cases of premature infants diagnosed with intraventricular hemorrhage， accounted for 45.45%（ 15/33）， and 18 cases of premature infants diagnosed with hypoxia ischemic change， accounted for 54.55%（ 18/33）. MRI results： the group with 62 cases in preterm infants found positive in intracranial lesions， whose rate was 51.67%（ 62/120）， including 34 cases diagnosed with the brain ischemia， 19 cases diagnosed parenchymal dotted hemorrhage， accounted for 30.66% （19/62）， 9 cases diagnosed with the brain ischemia combined subarachnoid hemorrhage， accounted for 14.52%（ 9/62）. Conclusion：The accuracy and sensitivity of MRI diagnosis for premature infants is obviously higher than that of amplitude integration of electroencephalogram（ EEG） and CDI. electroencephalogram（ EEG） to the integration of these amplitude can be premature abnormal changes of sleep-wake cycle for diagnosis， and　served as first diagnosis and follow-up tracking method applied in the clinical work.

2015 Vol. 12　(03):　126-128 [Abstract]（ 566 ） HTML (1 KB)  PDF  (664 KB)  ( 235 )

Objective： To explore a common complication of acute peritonitis after surgery， for reasons analyzed  and proposed treatment. Method： A retrospective analysis of the clinical data of 60 cases of patients with complications of acute peritonitis after surgery in our hospital from February 2008 to February 2014 were treated， the incidence of acute peritonitis causes and treatment of postoperative complications and comprehensive the study. Result： Abdominal visceral
organs endogenous infections and other bacterial infections caused postoperative complications； to prevented infection on the basis of active treatment of the primary disease， included aseptic protect the incision， abdominal pus or contents of drainage， adequate washing， and the rational used of antibiotics to reduced the generation of complications. This study of 60 patients in which 53 patients localized complications（ wound infection， incomplete intestinal obstruction， abdominal abscess and wound dehiscence） had been successfully treated； seven cases of systemic complications in three cases of illness in patients with severe potential death. After treatment， 56 cases of patients with successful treatment， the cure rate was 93.3%. Conclusion： Patients with acute postoperative complications peritonitis infection is mainly caused by the treatment process and therefore need to be cautious in the operation， to maximize prevention of infection， prevent the emergence of complications.

2015 Vol. 12　(03):　134-136 [Abstract]（ 703 ） HTML (1 KB)  PDF  (666 KB)  ( 341 )

DNA double strand breakage（ DSB） is the most significantly biological effect when cells are exposed to ionizing radiation（ IR） which may result in apoptosis， checkpoint arrest， cellular senescence and DSB repair. DNA damage response（ DDR） is activated with induction of DNA damage. The mechanisms involved in DSB repair include homologous recombination（ HR） and non-homologous end-joining（ NHEJ）. HR， a template-dependent and mostly error-free pathway， plays a crucial role in protecting genome fidelity from DSB. It can be divided into three phases including presynaptic， synaptic and postsynaptic phases. For the repair of DSBs caused by IR， HR is mainly restricted in G2 and S phases while NHEJ and HR function complementarily. HR is related to the risk of tumorigenesis， predicts the survival of several kinds of carcinoma and is a novel target of cancer therapy. This article has comprehensively reviewed
the progress in understanding of the mechanism of HR repair， its associated factors affecting the fidelity in DSB repair， the concept of synthetic lethality and its association with NHEJ repair. The potential of its clinical application by targeting specific DSB repair pathways is further explored.

2015 Vol. 12　(03):　143-146 [Abstract]（ 943 ） HTML (1 KB)  PDF  (714 KB)  ( 708 )

Fiber post and resin core systems were applied in the restoration of residual roots.At present， the restorative materials are gradually transferred from traditional rigid materials to composite materials whose biomechanical properties are close to dentin， such as fiber post.To restore endodontically treated teeth with fiber posts and composite resin，long term effect index is fracture resistance.This paper is focused on the influencing factors of fracture resistance of fiber posts.

2015 Vol. 12　(03):　150-152 [Abstract]（ 397 ） HTML (1 KB)  PDF  (654 KB)  ( 344 )