Objective：To observe the myocardial protective effect of the HTK solution in open heart operation for severe cardiac valve disease patients.Method：16 severe cardiac valve disease patients undergone open heart operation were received HTK solution for myocardial protection from April 2012 to March 2013， and their clinical data was compared with that of another 16 severe cardiac valve disease patients received cold blood cardioplegia for myocardial protection.
Result：The ratio of spontaneous cardiac rhythm recovery in the HTK solution group was higher than that of cold blood cardioplegia group（ P<0.05）.The average operation time， the cardiopulmonary bypass time， the aortic clamping time， the time from aorta declaming to heart rebeating， the assisted circulation time after aorta declaming， the mechanical ventilation support time， and the length-of-stay in ICU after operation in the HTK solution group were shorter than those of cold blood cardioplegia group（ P<0.05）.The dose of dopamine at the end of cardiopulmonary bypass was（ 5±2.5）μg/（kg·min），was less than that of cold blood cardioplegia group（ P<0.05）.The ratio of postoperative severe complications in the HTK solution group was also lower than that of cold blood cardioplegia group（ P<0.05）.The concentration of cTnI and CKMB was elevated after the onset of cardiopulmonary bypass， and the peak of cTnI and CKMB on the first postoperative day in two groups.The HTK solution group had lower cTnI and CKMB concentrations compared with cold blood cardioplegia group after cardiopulmonary bypass（ P ≤ 0.05）.Conclusion：The myocardial protective effect of the HTK solution in open heart operation for severe cardiac valve disease patients is better than that of cold blood cardioplegia.

2015 Vol. 12　(04):　1-5 [Abstract]（ 485 ） HTML (1 KB)  PDF  (692 KB)  ( 236 )

Objective：To assessed the effectiveness and security of bandag type corneal contact lens applied in
pterygium excision.Method：The prospective case-control study was used in the patients of pterygium.The 40 patients（ 40
eyes） who were received the pterygium excision were observed from March 2014 to June and randomly divided into two
groups：observation group and control group，20 cases in each group（20 eyes）.Observation group were wore the bandag
type corneal contact lens after surgery and taked it down at 5 d.The control group did not.The degree of pain after surgery
were evaluated at 2 h，1，2，3 and 5 d after surgery，meanwhile，corneal epithelium was evaluated by fluorescein
vital staining.Result：There are no significant differences between the observation and control group in the percentage of age and gender and size of the pterygium（P>0.05）.After surgery， the degree of pain at 2 h，1，2，3 and 5 d were as following：the score of observation group were（ 0.92±0.47）scores，（0.58±0.45）scores，（0.34±0.42）scores，（0.19±0.31）scores，（0.10±0.27）scores; the score of control group were（ 3.11±0.75）scores，（1.98±0.43） scores，（1.59±0.66）scores，（0.83±0.52）scores，（0.43±0.27）scores.The degree of pain of treatment group was significantly decreased compared to control group， the difference was statistically significant（ P<0.01）.After surgery at 5 d，the score of corneal epithelium stained with fluorescein between of observation group（ 0.76±1.31） and control group （1.28±1.45），the difference was statistically significant（P<0.05）.Follow-up was 2-6 months， no complications， such as infection， relapse， implant healing badness and subconjunctival cyst.Conclusion：The bandag type corneal contact lens could markedly release pain response after pterygium excision surgery， promote postoperative recovery， which is beneficial to reduce the postoperative recurrence rate and improve the postoperative quality of life.

2015 Vol. 12　(04):　8-11 [Abstract]（ 693 ） HTML (1 KB)  PDF  (668 KB)  ( 273 )

Objective：To study the effect of blocking the NF-κB signaling pathway on proliferation and apoptosis in human pancreatic cancer cell line SW1990 and its possible mechanism.Method：SW1990 cells were treated with different concentrations of NF-κB inhibitor Bay 11-7082（2.5 μmol/L，5 μmol/L 和10 μmol/L）， SW1990 cells morphological changes after treatment were observed under the optical microscope and fluorescence microscopy.CCK-8
assay was used to evaluate the growth influence of Bay 11-7082 on pancreatic cancer SW1990 cells， the flow cytometry was used to determine apoptosis in SW1990 cells.Western blot was used to detect the protein expression of caspase-3 and Bax.Result：A dose-dependent inhibitory effect of Bay 11-7082 on pancreatic cancer SW1990 cells was observed.The result of FCM indicated that treated with Bay 11-7082 exhibited a significant increase of apoptosis in a dose-dependent manner.The expression of caspase-3 and Bax was up-regulated in human pancreatic cancer SW1990 cells after treatment. Conclusion：Bay 11-7082 inhibits the proliferation of SW1990 cells， which is mediated by altering apoptosis-related genes through up-regulation of caspase-3 and Bax.

2015 Vol. 12　(04):　14-17 [Abstract]（ 463 ） HTML (1 KB)  PDF  (726 KB)  ( 251 )

Objective：To investigate the effect of pressure-controlled inverse ratio ventilation using laryngeal mask airway in gynecological laparoscopy.Method：Thirty patients between 18 and 60 years， American Society of Anesthesiologists class 1-3， scheduled for elective major gynecological laparoscopy were included in the study.Size 4 flexible LMAs were used for patients.Pressure-controlled ventilation（ PCV） was initiated with tidal volume 8 mL/kg，
inspiratory–expiratory（ I：E） ratio was kept 1：2， with positive end expiratory pressure（ PEEP） of 5 cm H2O.Intraoperative monitoring included noninvasive blood pressure， pulse oximetry， end-tidal carbon dioxide， 5-lead EKG，gas monitoring.After 15 min of pneumoperitoneum readings were recorded.I：E ratio was now changed to 1.5：1 on the mode PCV（ PCIRV） and PEEP of 5 cm H2O continued.Readings were taken after 15 min of PCIRV.Result：The peak and plateau pressures after pneumoperitoneum during PCV was（ 25.5±3.67） and（ 25.35±3.8） cm H2O， respectively
and during PCIRV（ 25.8±3.86） and（ 25.8±3.41） cm H2O， respectively， and was statistically similar.The mean airway pressure during PCV（ 13.5±1.35） cm H2O was lower than PCIRV（ 17.30±2.08） cm H2O（ P<0.01）.Tidal volume on PCIRV（ 502±49.19）mL was significantly higher as compared to PCV（ 450±38.25） mL.The dynamic compliance on PCIRV（ 24.8±4.25）mL/cm H2O was also significantly higher than PCV（ 21.50±3.9）mL/cm H2O.Conclusion：PCIRV  with I：E ratio 1.5：1 can be an effective mode of ventilation in major gynecological laparoscopy using LMA.

2015 Vol. 12　(04):　21-23 [Abstract]（ 541 ） HTML (1 KB)  PDF  (650 KB)  ( 198 )

Objective：Through the analysis of plasma EBV-DNA quantification in advanced nasopharyngeal carcinoma（ NPC） in different stages， further confirmed that plasma EBV-DNA quantification in diagnosis and staging of nasopharyngeal carcinoma， and the clinical significance.Method：Using real-time quantitative polymerase chain reaction assay in 60 patients with advanced nasopharyngeal carcinoma peripheral plasma EBV-DNA level.Result：Ⅲ， Ⅳa， Ⅳb NPC EBV-DNA positive rate was 100%； the median copy number was 6.00×103 copies/mL in Ⅲ stage； the median copy number was 15.15×103 copies/mL in Ⅳa stage； the median copy number was 43.60×103 copies/mL in Ⅳb+Ⅳc stage. Conclusion：There are obvious differences in different patients with newly diagnosed advanced nasopharyngeal carcinoma staging of nasopharyngeal carcinoma in peripheral plasma EBV-DNA level.

2015 Vol. 12　(04):　27-30 [Abstract]（ 535 ） HTML (1 KB)  PDF  (669 KB)  ( 520 )

Objective：To study the relationship among the state of post stroke depression， the degree of neurological impairment and the responsible lesion site.Method：160 patients with acute cerebral stroke were tested and the degrees of neurological impairment and were graded by introducing Hamilton Depression Rating Scale.35 patients were found with post stroke depressive state.Statistic analysis was done under conditions of different relative factors.Result：The total incidence of post stroke depression was 21.9%， which was positively correlated to the degree of neurological impairment significantly.The left hemisphere lesions were prone to depression than the right ones.The basal ganglia injuries were prone to depression.Conclusion：The severe neurological dysfunction can promote the occurrence of depression， and the occurrence of post stroke depression is associated with the responsible lesion site.

2015 Vol. 12　(04):　33-34 [Abstract]（ 536 ） HTML (1 KB)  PDF  (629 KB)  ( 163 )

Objective：To discuss and analyze Pulmicort Respules combined with azithromycin clinical observation on the treatment of Mycoplasma pneumoniae infection in children.Method：102 cases with mycoplasma pneumonia were randomly selected in our hospital from 2012 December to 2013 December period as the object of study，according to the random double blind method， 102 patients were divided into observation group and control group， control
group contained 51 cases， using azithromycin， the observation group contained 51 cases added Pulmicort treatment on the basis of the control group， the clinical efficacy after treatment of the two groups was observed， as well as hospitalization time， symptoms disappear time， adverse reaction.Result：The cure rate and total effective rate of the observation group was 52.94%（ 27 cases）， 94.11%（ 48 cases） respectively， which was significantly higher than 31.37%（ 16 cases），80.39%（ 41 cases） of the control group， there were statistically significant differences （ P<0.05）.The hospitalization time， symptoms disappeared time， and adverse reactions of the observation group was lower than that of the control group，there were statistically significant differences（ P<0.05）.Conclusion：Pulmicort Respules combined with azithromycin in treatment of children with mycoplasma pneumonia has curative effect， and the hospitalization time and adverse reactions are less， get favorable comments from the families of the children， worthy of promotion and application in clinical.

2015 Vol. 12　(04):　38-40 [Abstract]（ 508 ） HTML (1 KB)  PDF  (648 KB)  ( 229 )

Objective：To investigate the clinical efficacy of different treatment methods on early onset preeclampsia.Method：96 cases of early pregnant women in the sampled in our hospital， were randomly divided into three groups， the group of magnesium sulfate， magnesium sulfate and low molecular heparin group（magnesium sulfate+LMWH group）， magnesium sulfate+low molecular weight heparin+Salvia miltiorrhiza hiza group（ magnesium sulfate+LMWH+SM group），32 cases in each group.Through the observation of pregnancy outcome， the changes of blood pressure， APTT
value， newborn and to determine the clinical effects of the three groups.Result：Three groups of patients with blood pressure and APTT value were compared before and after treatment，the differences were statistically significant（P<0.05）; magnesium sulfate group of neonatal asphyxia incidence was highest of 62.5% and the neonatal survival rate was the lowest of 87.5%，compared with other two groups had significant difference（ P<0.05）。Three groups of patients with treatment time and neonatal weight were compared，there were no significant differences.Conclusion：Magnesium sulfate+low molecular weight heparin+salvia miltiorrhiza combined treatment of early onset preeclampsia have best effect，worthy of
clinical application.

2015 Vol. 12　(04):　44-46 [Abstract]（ 495 ） HTML (1 KB)  PDF  (649 KB)  ( 202 )

Objective：To study clinical role and application value of CT examination in early cerebral infarction. Method：To retrospectively analyze 90 patients with early cerebral infarction who accepted CT examination during March 2013 to November 2013.They accepted CT examination 1-6 h after the onset（ control group） and 24 h after the onse（ research group） respectively， comparatively observed the results after inspection.Result：Patients with two test
results were all positive， and the lentiform nucleus， middle cerebral artery high-density shadow， fuzzy boundaries early low density shadow， mild placeholder and brain sulcus disappeared status enhancement rate in research group were significantly higher than that of control group， the results had statistical significance（ P<0.05）.Conclusion：CT imaging in patients with early cerebral infarction can find accurate detection of the development status as soon as possible， it has a great significance in diagnosis and treatment of early cerebral infarction， check after 24 hours for the first time can
effectively ensure the accuracy of the results.

2015 Vol. 12　(04):　50-52 [Abstract]（ 470 ） HTML (1 KB)  PDF  (649 KB)  ( 177 )

Objective：To investigate the efficacy of early short methylprednisolone pulse therapy and dexamethasone in treatment of children with severe viral encephalitis.Method：120 cases with severe viral encephalitis were selected from our hospital during the period from June 2012 to June 2014， they were randomly divided into observation group and control group accordance to a digital list france， the observation group was early methylprednisolone
pulse therapy using short， the control group was treated with dexamethasone， the symptoms and signs the recovery time， and clinical efficacy of the two groups were compared.Result：（1） Clinical symptoms and signs recovery time of the observation group was significantly shorter than recovery time of the control group， the difference was statistically significant（ P<0.05）.（2） Effect good rate of the observation group was significantly higher than the that of the control group， the difference was statistically significant（ P<0.05）.Conclusion：Early short methylprednisolone pulse therapy in treatment of children with severe viral encephalitis has exact clinical efficacy， and can be restored as soon as the patient signs and symptoms.

2015 Vol. 12　(04):　55-57 [Abstract]（ 537 ） HTML (1 KB)  PDF  (649 KB)  ( 216 )

Objective：To analyze the epidemiologic data of acute pyelonephritis with pregnancy in Dongguan district.Method：483 patients of acute pyelonephritis with pregnancy were enrolled from January 2012 to December 2013.Morbidity of acute pyelonephritis with pregnancy， symptom and complication， spectrum of pathogen， tolerance，prognosis were investigated.Result：Morbidity of acute pyelonephritis with pregnancy was 3.13%，morbidity of acute pyelonephritis with pregnancy in 2013 for 3.69% was significantly higher than that in 2012 for 2.47%，the difference was statistically significant（P=0.000）.Symptom and complication included pyrexia>38.3 ℃ were 429 cases for 88.82%，anemia（hemoglobin<90 g/L）were 265 cases for 54.87%， acute kidney dysfunction（baseline creatinine increased 1.5 times）were 89 cases for 18.43% and electrolyte disorder were 58 cases for 12.01%.In 483 were a total of 392 urine cultures were positive，including bacillus were 229 cases accounted for 58.42%， coccus were 117 cases accounted for 29.85%， fungi were 46 cases accounted for 11.73%，the major pathogen were as follows：escherichia coli for 40.82%，
staphylococcus saprophyticus for 16.58%， klebsiella pneumonia for 11.22% and enterococcus faecalis for 8.16%.Morbidity of fungal infection in 2013 for 14.40% was significantly higher than that in 2012 for 7.04%， the difference was statistically significant（ P=0.044）.Detectable rate of candida tropicalis in 2013 for 8.00% was significantly higher than that in 2012 for 1.41%， the difference was statistically significant（P=0.013）.Escherichia coli， staphylococcus saprophyticus，klebsiella pneumonia were sensitive to common antibiotics.Pregnancy outcomes in patients with acute pyelonephritis
was better.Conclusion：Morbidity of acute pyelonephritis with pregnancy is high.We could pay more attention to fungal infection.

2015 Vol. 12　(04):　61-64 [Abstract]（ 536 ） HTML (1 KB)  PDF  (669 KB)  ( 123 )

Objective：To observe the TORCH infection rate of rural pre-pregnancy women in Liaoning province from 2011 to 2013.Method：Enzyme-linked immunosorbent（ ELISA） was used to detect the serum and the results were entered into the national free pregnancy health examination information system.Result：Among the 193 490 pregnant women for inspection， the positive rates of serum rubella virus IgG antibody，cytomegalovirus IgG and IgM antibodies，and toxoplasma IgG and IgM antibodies was 55.58%， 0.78%， 51.58%， 0.48% and 1.61%.Municipal infection rate was statistically significant（ P<0.05）.Conclusion：In cities of liaoning province TORCH infection rates difference is bigger，according to the infection characteristics of cities， formulate the corresponding prevention and control measures， reducing the occurrence of intrauterine infection， improve the eugenics.

2015 Vol. 12　(04):　68-70 [Abstract]（ 574 ） HTML (1 KB)  PDF  (648 KB)  ( 372 )

Objective： To explore the cluster nursing psychological state in patients with threatened abortion and the influence of life indicators. Method： Selection from January 2012 to December 2013 in hospital obstetrics and gynecology hospital treatment of 88 cases of threatened abortion of pregnant women as the research object， they were randomly divided into observation group and control group， observation group with normal nursing method， the control
group in the application of cluster on the basis of conventional nursing care. To compare nursing effect of the two groups.Result： There were 40 cases in the observation group were markedly improved， the total effective rate was 90.1%， and 35 cases in the control group were markedly improved， the total effective rate was 79.5%， the nursing effect of the observation group was obviously better than that of the control group， with significant differences（ P<0.05）. Conclusion： The cluster of targeted to enhance nursing mode can improve patients in recognition of threatened abortion， improve clinical curative effect， reduce the occurrence of complications and nursing effect is more obvious， has clinical significance.

2015 Vol. 12　(04):　74-75 [Abstract]（ 478 ） HTML (1 KB)  PDF  (628 KB)  ( 336 )

Objective： To explore evidence-based nursing（ EBN）’s application and effect on nursing postoperative patients with cervical anastomosis fistula of esophageal cancer. Method： 27 postoperative patients with cervical anastomosis fistula of esophageal cancer from January 2012 to December 2013（ after the application of EBN）were selected as observation group， and were given EBN.25 postoperative patients with cervical anastomosis fistula of
esophageal cancer from January 2010 to December 2010（ before the application of EBN） were selected as control group，and were given conventional nursing measures. Two groups’ clinical outcome， anastomotic fistula healing time， nursing quality score and patients satisfaction were compared.Result： Except 1 patient transferred to another hospital during treatment in control group， the others’ healing rate of postoperative anastomotic fistula was 100% in the two groups.Average healing time of the observation group was shorter than that of control group（ t=4.68， P<0.05）， yet nursing quality score was higher than that of control group（ t=4.29， P<0.05）， and patient satisfaction was higher than that of control group（ 字2=4.53，P<0.05）. Conclusion： It has good effect of EBN’s application on nursing postoperative patients with cervical anastomosis fistula of esophageal cancer， not only detailings nursing care measures， improves nursing quality，but also promotes the harmonious relationship between nurses and patients， and healing time is shorten， so it embodies nursing’s knowledge value.

2015 Vol. 12　(04):　79-82 [Abstract]（ 523 ） HTML (1 KB)  PDF  (670 KB)  ( 245 )

Objective： To investigate the effect of daily work path on performance of head nurse， and improve their work efficiency. Method： Eighteen wards of our hospital from March 1， 2014 to March 31， 2014 were set as control group， and the same 18 wards from April 1， 2014 to April 30， 2014 were set as observation group. In the control group，the performance of head nurses was evaluated in the conventional way， while in the observation group， a daily work routine was established as required by their work， and the head nurses were asked to work according to the work routine every day and evaluate quality assessment. Rate of qualified basic care， rate of improper administration， satisfaction of patients，and satisfaction of fellow nurses with the head nurses were then compared between the two groups. Result： Compared to the control group， the observation group showed much higher rate of qualified basic care， satisfaction of patients，and satisfaction of fellow nurses， and lower rate of improper administration（ P<0.01）， with statistical significance. Conclusion： The establishment of daily work routine and evaluate can help head nurses better review and improve the quality of ward nursing， so it is a mode worth spreading.

2015 Vol. 12　(04):　88-91 [Abstract]（ 482 ） HTML (1 KB)  PDF  (665 KB)  ( 296 )

Objective： To observe the clinical manifestation of the patients with diabetes foot infections and explore the synthetic nursing process of lower limbs ulcer surface so as to evaluate the intervention effectiveness. Method： A total of 203 diabetic patients who were treated in the hospital from 2009 to 2014 were randomly divided into the comprehensive nursing group of 101 patients and the routine nursing group of 102 patients. Both groups were treated the same treatment and normal nursing， while the comprehensive nursing group was treated with synthetic nursing intervention. Result： After the treatment and nursing， both groups developed but the comprehensive nursing group had 58（57.4%） of degree 0， while the routine nursing group had 42（41.2%），the difference was statistically significant（P<0.05）.The two groups of infection were controlled with a decreasing infection rate，the comprehensive nursing group was better than the routine nursing group. And the comprehensive nursing group of total effective rate was 94.1% higher than the routine nursing group of 82.4%，the difference was statistically significant（P<0.05）.Conclusion： The comprehensive nursing group has a higher total control the systemic condition， improve the local microcirculation and wound healing， reduce the incidence of infection， and significantly improve the therapeutic effect.

2015 Vol. 12　(04):　95-97 [Abstract]（ 531 ） HTML (1 KB)  PDF  (648 KB)  ( 198 )

Objective：To research clinical efficacy， adverse psychology and quality of life of system nursing intervention on patients with chronic gastritis and gastric ulcer.Method：110 patients with chronic gastritis and gastric ulcer in our hospital were randomly divided into study group（ 55 cases） and control group（ 55 cases） according to random number table method.The control group was given conventional nursing， the study group was treated by system nursing intervention.The clinical efficacy of the two groups were observed， and the psychological status and quality of life of the two groups were evaluated.Result：After treatment， the effect rate of the study group was 92.73%， which was significantly higher than 72.73% in the control group（ P<0.05）.After treatment， the psychological status and life quality of the two groups were improved significantly.The study group psychological status of SAS and SDS scores was（ 38.84±5.15） and （35.92±4.03） points， which reduced significantly than the control group， and the quality of life for SF-36 score was （78.92±6.84） points， which increased significantly than the control group.Conclusion：System nursing intervention can improve the efficacy of clinical treatment in patients with chronic gastritis， gastric ulcer， and can effectively improve the patient’s psychological status and quality of life， which is worthy to be popularized in clinical application.

2015 Vol. 12　(04):　101-103 [Abstract]（ 659 ） HTML (1 KB)  PDF  (648 KB)  ( 452 )

Objective：To discuss the application and effect of detail management in medical waste management of dermatology and venereology clinic.Method：Details management such as consummating management systems，strengthening staff training， increasing input of environmental equipment， regulating the collection link of medical waste，organizing regular joint inspections were implemented to regulate the medical waste management.Result：The management effect indicators of medical waste after implement the detail management were more superior to before（ P<0.01）.The costs of medical waste was 18.39%.The occurrence rate of traumatic medical waste after detail management implement was lower than before（ P<0.05）.Conclusion：Detail management is an effective scientific management method which could prevent and control the hospital infection effectively and is helpful for training the employees’ saving consciousness.It is also helpful for establishing an economy type hospital and decreasing the incidence of occupational exposure.

2015 Vol. 12　(04):　106-108 [Abstract]（ 455 ） HTML (1 KB)  PDF  (648 KB)  ( 203 )

Objective：To analyze the effectiveness of polymyxin B in combination with meropenem for pan-drug resistant pseudomonas aeruginosa vitro antimicrobial activity.Method：After polymyxin B and meropenem were used alone and used together， the minimum inhibitory concentration of the 60 strains of pan-drug resistant pseudomonas aeruginosa which were clinically separated was tested through broth dilution method， checkerboard method and so on.And also the fractional inhibitory concentration index（ FIC） was calculated.At the same time， the type and the effectiveness of the joint effect was determined according to the fractional inhibitory concentration index.Result：After the joint use of Polymyxin B and Meropenem， the fractional inhibitory concentration index of the medicine on the pan-drug resistant pseudomonas aeruginosa significantly reduced.Among these 60 strains of pan-drug resistant pseudomonas aeruginosa， those whose FIC at 0-0.5 accounted for 60%， at 0.5-1.0 accounted for 30%， at 1.0-2.0 accounted for 10%， but none of them whose FIC was over 2.Conclusion：When Polymyxin B and Meropenem are used together， they are mainly dominated by synergistic and additive effect.The 60 strains of pan-drug resistant pseudomonas aeruginosa which are separated have antibacterial effect.However， they do not have antagonistic effects.

2015 Vol. 12　(04):　112-115 [Abstract]（ 607 ） HTML (1 KB)  PDF  (665 KB)  ( 191 )

Objective：To analyze nonsocial infection of patients in department of cardiology， provide the basis for the prevention and treatment of hospital infection， and promote the patient’s rehabilitation work.Method：600 patients hospitalized in department of cardiology during January 2013 to April 2014 were selected to retrospectively analyze.Result：45 cases in 600 patients with cardiovascular disease occurrences nonsocial infection.The infection rate was 7.5%.One of the most common infection was respiratory tract infection， accounted for 48.9%.The main pathogenic bacteria was Gram-negative bacteria， accounted for 64%.Mainly affected by pseudobulbar paralysis， long period of hospitalization，advanced age， underlying diseases， invasive operation， heart function and other factors.Conclusion：The patients in department of cardiology are more susceptible factors， so the nosocomial infection rate is higher.Rational uses of drugs and preventive measures should be actively taken.

2015 Vol. 12　(04):　119-122 [Abstract]（ 446 ） HTML (1 KB)  PDF  (665 KB)  ( 158 )

Objective：To investigate the sonographic features of color Doppler ultrasound in the diagnosis of placenta accreta.Method：22 cases with placenta accreta prenatal or postnatal color Doppler ultrasound were retrospectively analyzed.Result：In 22 cases with placenta accreta prenatal ultrasound， 3 cases were diagnosed before delivery， and 19 cases did after delivery.Conclusion：The application of color Doppler ultrasound for diagnosis of placenta accreta， for pregnant women， postpartum when processing plays an important role.Application of ultrasonic observation of prenatal， postpartum placenta implantation， convenient， non-invasive， no pain， accurate and reliable， can be directly observed， can provide reliable diagnostic basis for clinical.

2015 Vol. 12　(04):　126-128 [Abstract]（ 516 ） HTML (1 KB)  PDF  (713 KB)  ( 181 )

Objective：To evaluate the preventive and curative effects of recombinant human interleukin 11 （rhIL-11） for malignant tumor patients after chemotherapy induced severe thrombocytopenia.Method：58 patients with malignant tumor after chemotherapy induced severe thrombocytopenia were enrolled in the study， in the presence of severe thrombocytopenia after treated were given rhIL-11（ as treatment period）; all the patients in the next cycle of chemotherapy at 48 h after administration were given rhIL-11 preventive treatment（ as prevention and treatment period）. The 2 cycle degree of thrombocytopenia and duration were observed by using own control methods.Result：The effective rate of treatment period was 100%（58/58）;the treatment period and the prevention in treatment period on medication duration was respectively（10.9±5.7）d and（ 5.3±3.8）d;thrombocytopenia duration was respectively（11.6±5.8）d and（5.2±3.9）d; platelet minimum were respectively（25.9±15.7）×109/L and（42.3±18.8）×109/L， the differences were statistically significant（P<0.05）.The incidence rate of adverse reaction in treatment period was 29.3%（17/58），and in prevention treatment period was 25.9%（ 15/58），the difference was not statistically significant. Conclusion：RhIL-11 can promote the recovery of patients with malignant tumor chemotherapy induced severe thrombocytopenia，reduce the incidence of severe thrombocytopenia，and shorten the duration of severe thrombocytopenia
with mild adverse reaction， also the patients can tolerate.

2015 Vol. 12　(04):　132-134 [Abstract]（ 406 ） HTML (1 KB)  PDF  (650 KB)  ( 196 )

Objective：To analyze lifestyle interventions used in physical examination population with high risk of chronic disease.Method：We selected 1000 chronic disease in high-risk population from June 2014 to June 2013 in our hospital for health examination as the research object， according to the results of physical examination and questionnaire survey results to formulated and implemented of the lifestyle intervention program， physical examination index，biochemical changes and cardiovascular risk factors were compared before and after the intervention of high-risk chronic disease in physical examination population.Result：After the intervention， research object BMI， waist circumference，systolic and diastolic blood pressure improved significantly higher than those before intervention， the differences were statistically significant（ P<0.05）.After the intervention， the research object of fasting blood glucose， TC， TG， HDL-C and LDL-C was significantly better than before the intervention， the differences were statistically significant（ P<0.05）.
Conclusion：Strengthen lifestyle intervention can effectively improve the unhealthy lifestyle of physical examination population with high risk of chronic disease， effective control of risk factors of chronic diseases， and is worthy of further inquiry.

2015 Vol. 12　(04):　138-140 [Abstract]（ 465 ） HTML (1 KB)  PDF  (649 KB)  ( 178 )

Objective：To investigate the laminae and spinous-interspinous ligament combined tissue flap grafting technique points back to the surgical treatment of degenerative lumbar spinal canal stenosis and curative effect.Method：66 cases were selected， male 25 cases， female 41 cases，53-81 years old， average 67 years old.Part of the lumbodorsal fascia，supraspinal ligament，interspinal ligament and periosteum retention of vertebral lamina were
reserved， in lesion segment next vertebra clearance off spine-interspinal ligament， with low speed electric drill or chisel，in the medial facet， from the bottom to the top along the vertebral sagittal full-thickness wedge osteotomy， until the entire lesion segment， to pull the lamina and the supraspinous and interspinous ligaments， routine decompression， spinous process and lamina combined tissue flap grafting back surgery.Result：66 cases were followed up， the longest 7 years，the shortest 8 months， average 46 months.The total excellent rate was 89.3%.Conclusion：This technique increases
the sagittal diameter of spinal canal， expanding vertebral canal volume， is conducive to reducing.Lamina and spinousinterspinal ligament combined tissue flap grafting to form physiological tube structure， restore stability of the spine and three pillars， both to prevent iatrogenic spinal epidural scar tissue hyperplasia formation between organizations and narrow， and preventing the spinal posterior column instability.Show a wide range， complete decompression of spinal canal， the re forming， effective prevention of postoperative complications of spinal instability， intractable lumbago and so on.

2015 Vol. 12　(04):　143-146 [Abstract]（ 515 ） HTML (1 KB)  PDF  (655 KB)  ( 225 )

Objective：To study application of color Doppler ultrasonography to diagnosis of priapism.Method：From 2003 to 2013， our hospital received and cured 16 patients with ultrasonic diagnoses of priapism and analyzed and compared two types of ultrasonic diagnoses applications of Priapism.Result：Among those patients， four cases had high flow priapism and twelve cases had low flow priapism.For those two kinds of priapism， their two- dimensional ultrasonoscopy of cavernosal were different and there were significant differences between their blood velocities of color Doppler corpus cavernosal artery and penis deep dorsal veins.Conclusion：Due to its non-invasion， color Doppler ultrasonography has specific ultrasonography findings.Color Doppler ultrasonography is one of the most valuable preferred methods for clinical classification diagnosis of priapism.

2015 Vol. 12　(04):　149-151 [Abstract]（ 394 ） HTML (1 KB)  PDF  (646 KB)  ( 390 )