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| Expression of Different Levels of Plasma EBV-DNA in Patients with Advanced Nasopharyngeal Carcinoma/ |
| The Affiliated Hospital of Zunyi Medical College， Zunyi 563003， China |
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Abstract Objective：Through the analysis of plasma EBV-DNA quantification in advanced nasopharyngeal carcinoma（ NPC） in different stages， further confirmed that plasma EBV-DNA quantification in diagnosis and staging of nasopharyngeal carcinoma， and the clinical significance.Method：Using real-time quantitative polymerase chain reaction assay in 60 patients with advanced nasopharyngeal carcinoma peripheral plasma EBV-DNA level.Result：Ⅲ， Ⅳa， Ⅳb NPC EBV-DNA positive rate was 100%； the median copy number was 6.00×103 copies/mL in Ⅲ stage； the median copy number was 15.15×103 copies/mL in Ⅳa stage； the median copy number was 43.60×103 copies/mL in Ⅳb+Ⅳc stage. Conclusion：There are obvious differences in different patients with newly diagnosed advanced nasopharyngeal carcinoma staging of nasopharyngeal carcinoma in peripheral plasma EBV-DNA level.
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| [1] |
YANG Junjie,ZHONG Yanping,MAO Jing,LIU Xinhua,LI Shan,LIU Yuanyuan,LEI Xu,LEI Feifei,LEI Yu,GUO Peng,HU Bo,LIU Zhixin,TAN Huabing. Effect of Plasma Exchange Combined with Double Plasma Molecular Adsorption System on Hepatocyte Regeneration in Hepatitis B Virus-associated Acute-on-chronic Liver Failure[J]. 中国医学创新, 2023, 20(5): 63-69. |
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