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中国医学创新

15 Vol.12,No.08

Published 2016-03-15

LIU Rong-qiang,LI Xiao-guang,ZHAO Chun-rong,et al.

Objective: To observe and compare the clinical efficacy and adverse reaction of deoxynucleotide injection combined with chemotherapy in of human middle-late non-small cell lung cancer. Method: 62 cases of nonsmall cell lung cancer patients were selected by multicenter and randomized controlled clinical trial method from March 2013 to March 2014. All patients were divided into two groups,the control group of 32 cases who were treated with chemotherapy and granulocyte colony-stimulating factor, and the experimental group of 30 cases who were treated with deoxynucleotide injection 200 mg/d on the base of control group.After 2,7,14 d continuous treatment,the levels of white blood cells and platelet were assessed, the occurrence of III+IV bone marrow suppression was recorded, the immune function,weight,and quality life scores of patients were assessed.Result: The treatment group after 7 d WBC count was (4.2±1.2)×109/L,platelet count was( 67.4±13.2)×109/L,WBC normal persons accounted for 73.3%,the III+IV
bone marrow suppression rate was 13.3%;the control group was respectively(3.1±1.1)×109/L,(46.8±17.8)×109/L,31.3%,56.3%,the differences were statistically significant(P<0.05).Followed 14 d, the treatment group of CD3+,CD4+,CD4+/CD8+,NK cells were respectively( 54.7±8.2)%,(39.2±4.5)%,(31.2±10.2)%,(1.33±0.29);the control group of CD3+,CD4+,CD4+/CD8+,NK cells were respectively( 48.3±6.6)%,(31.3±5.0)%,(24.3±8.9)%,(1.01±0.18), the treatment group’s levels were better than the control group, the differences were statistically significant(P<0.05). Followed 21 d, the treatment group muscle aches/weakness events,liver injury(ALT,AST,or TBI exception) incidence rate was respectively 6.6%,3.3%,the control group was respectively 40.6%, 21.9%,another treatment group gained an average of( 1.8±0.3)kg, the control group of( -0.4±0.2)kg,the differences were statistically significant(P<0.05).Conclusion: Deoxynucleotide injection reduce the degree of bone marrow suppression caused by chemotherapy, improve the patient’s weight, immune function and quality of life scores.

15 Vol. 12 (08): 1-3 [Abstract]( 636 HTML (1 KB)  PDF  (706 KB)  ( 170 )

ZHONG Jie-xia.

Objective:To Observe the protective effect of pantoprazole capsules with fengliao changweikang on human gastric epithelial GES-1 cells injured ethanol. Method: Human gastric epithelial GES-1 cells were cultured in vitro,incubated with different concentrations of ethanol,and observed at different time periods in order to establish a stable gastric mucosal injury model. Pantoprazole and fengliao changweikang capsules were formulated into different concentrations, MTT were used to observe the GES-1 cells intervention by two drugs alone and in combination.Result:Incubated at 7% ethanol for 3 h, human gastric epithelial GES-1 cells inhibition rate reached 40%, and this was the best model of injured gastric mucosal cell.Each concentration of pantoprazole and fengliao changweikang capsules had a protective effect on the GES-1 cells, the optimum concentration of both drugs were 60 μg/mL and 200 μg/mL, in combination with two drugs could reduce the dose and enhance the protective effect of the gastric mucosa. Conclusion:Combining with pantoprazole and fengliao changweikang capsules can improve medication safety, reduce the dosage, protect human gastric epithelial damage GES-1 cells at low doses,and they are worth promoting in clinical.

15 Vol. 12 (08): 4-6 [Abstract]( 536 HTML (1 KB)  PDF  (697 KB)  ( 226 )

ZHU Shi-bin,ZHAO Guo-hua.

Objective:To evaluate and compare the effects of anterior approach preperitoneal repair of inguinal hernia with 3DMax mesh and UHS mesh.Method: 90 patients were treated by inguinal hernia repair during June 2010 and June 2013 in our hospital,including the operation time,wound infection and swelling complications,time for recovery to normal life and work,short-term(0.5-1.0 year after operation)recurrence rate,pain in 4 weeks,chronic pain and the occurrence rate of foreign body sensation in 6 months of two groups were compared.Result:There was no statistical difference between the two groups in the operation time,time for recovery,postoperative pain or neuralgia in 4 weeks(P>0.05).However,compared with 3DMax mesh UHS mesh caused more chronic pain or neuralgia in 4 weeks and foreign body sensation in 6 months after operation,the differences were statistical difference(P<0.05).No incision infection or hematoma showed in the two groups and no relapse found one year after operation. Conclusion:3DMax mesh has similar clinical effects with UHS mesh in inguinal hernia repair,but with a lower complication rate,it is prospectively a better clinical method for repairing hernia in future.

15 Vol. 12 (08): 7-9 [Abstract]( 606 HTML (1 KB)  PDF  (692 KB)  ( 152 )

HUANG Hong-li,SHI Cheng-hong.

Objective:To study the value of adenosine deaminase from pleural effusions and T-SPOT in diagnosis of tuberculous pleurisy.Method:Selected 112 cases of tuberculous patients as the observation group,42 cases of patiens with non-tuberculous exudative pleural effusion to the control group, two groups of patients were detected both ADA and T-Spot.Result:Two groups of patients with Pleural effusion test results,the sensitivity of ADA and T-Spot were 87.50% and 89.28%,respectively.The specificity of ADA and T-Spot were 88.09% and 92.85%.Combination of two methods of detection positive rate was 95.54%.Two detection methods there was statistically different( P<0.05).Conclusion:Combination of two methods can improve the positive rate,the diagnosis of tuberculous pleurisy provide a good basis,a better laboratory diagnostic tool,has a high value and broad application prospects.

15 Vol. 12 (08): 10-12 [Abstract]( 484 HTML (1 KB)  PDF  (692 KB)  ( 185 )

LI Min,WU Li,LIU Zhen,et al.

Objective:To investigate the effects of Sufentanil post-conditioning on renal injury induced by hepatic ischemia-reperfusion in rats.Method:Fifty-four Wista rats were randomly allocated into three groups(n=18):Sham operation group(S group),hepatic ischemia-reperfusion group(I/R group) and Sufentanil post-conditioning group(SP group).The rats were killed at the same time to obtain the renal tissue and take blood from the heart after hepatic ischemia 1 hour reperfusion for 2,4 and 6 hours,then tested cystatinC(CysC),observed the pathological changes in renal tissue,detected the expression of Bcl-2 and Bax proteins in kindy by immunohistochemistry and the apoptosis index(AI)of the renal cells was observed by Tunel method.Result:Compared with the S group,CysC,AI and the expression of Bcl-2 and Bax proteins incresed in I/R group and SP group.Compared with the I/R group,CysC,AI and the expression of Bax protein decresed but the expression of Bcl-2 protein incresed in SP group.Conclusion:The protective effects of  Sufentanil post-conditioning on renal injury induced by hepatic ischemia-reperfusion in rats may be related to the decresed expression of Bax protein and the incresed expression of Bcl-2 protein.

15 Vol. 12 (08): 13-15 [Abstract]( 525 HTML (1 KB)  PDF  (713 KB)  ( 154 )

CHENG Jiang-tao,DU Ting-hai,CHEN Peng,et al.

Objective:To reseach the clinical character of the heart rate variability(HRV) and QT dispersion in the patients with coronary heart disease(CHD).Method:The patients with coronary heart disease by coronary angiography confirmed(CHD group,n=78) and normal coronary angiography examiners(control group,n=64) were chosen and given 24 h dynamic electrocardiogram monitoring.The parameters of HRV and QT dispersion were calculated,and the features of these parameters were compared and analyzed between the two groups.Result:HRV(SDNN,SDANN,RMSSD,pNN50,TP and HF )decreased in CHD group compared with control group(P<0.05),while QT dispersion prolonged in CHD group compared with control group(P<0.01).Conclusion:HRV is decreased and QT dispersion is prolonged in CHD patients.

15 Vol. 12 (08): 20-22 [Abstract]( 503 HTML (1 KB)  PDF  (695 KB)  ( 200 )

CHEN Kai-zheng.

Objective:To observe the curative effect of Pulmicort Respules inhalation combined with oral montelukast in treatment of infant bronchiolitis.Method:80 infants with bronchiolitis were randomly divided into the experimental groupand the control group,with 40 cases in each group.The control group was given conventional therapy plus Xiyanping atomization combined with montelukast oral.The experimental group was given routine treatment Pulmicort Respules make comfortable atomization inhalation combined with montelukast oral.The main clinical symptoms and physical signs disappeared time and hospitalization time of the two groups after treatment were observed.Result:The total effective rate of experimental group(92.5%) was significantly higher than that in the control group(82.5%)(P<0.05).In the experimental group,the clinical symptoms and signs remission time and hospital stay were significantly shorter than the control group(P<0.05).Conclusion:Pulmicort Respules aerosol inhalation combined with oral montelukast for efficacy is better in the treatment of bronchiolitis,can relieve patients clinical signs and symptoms,shorten the hospitalization time,better safety, meaningful clinical promotion.

15 Vol. 12 (08): 22-24 [Abstract]( 499 HTML (1 KB)  PDF  (693 KB)  ( 149 )

LU Yan,ZHANG Lu-mei.

Objective:To investigate the diagnostic value of transvaginal color Doppler er ultrasound( TVCDS)combined with the colposcopy’s detection in early cervical carcinoma( ICC) and precancerous lesions(CIN).Method:120 cases of suspected patients with early cervical cancer and precancerous lesions were treated TVCDS underwent colposcopy examination, histopathological examination confirmed CIN42 cases,ICC34 cases, 44 cases of
cervical inflammation, analysis of early ICC, CIN and cervical inflammation TVCDS sonogram performance and joint diagnosis ICC,CIN accuracy, specificity and sensitivity.Result:(1)This situation could be discovered that the incidence and severity of cervical increases were higher than cervical inflammation for early CIN and ICC, because of the higher incidence of abnormal with the cervical canal endometrial line,and the richer of blood flow than cervical inflammation, so the difference were statistically significant(P<0.05).(2)The examination method sensitivity,specificity and accuracy of TVCDS combined with the colposcopy which was significantly higher than only TVCDS examination,and the difference were statistically significant(P<0.05).Conclusion:As the method can be improved the diagnostic accuracy rate with ICC and CIN that is TVCDS combine with the colposcopy,so there have a higher clinical value to formulate the early treatment plan.

15 Vol. 12 (08): 25-27 [Abstract]( 509 HTML (1 KB)  PDF  (704 KB)  ( 193 )

XU Li-wei.

Objective:To compare the prognosis situation of radical resection of laparoscopic rectal cancer and open radical operation. Method:100 cases of cancer patients were selected in our hospital from August 2012 to May 2013. According to the different treatment methods, they were divided into the observation group and control group,50 cases in each group. The observation group was performed laparoscopic resection, the control group with traditional open operation treatment, clinical parameters, resection of the recurrence after operation, postoperative complications and survival rate were compared.Result: In the observation group, the amount of bleeding during the operation, incision size, intestinal function recovery time, hospitalization time and other clinical parameters were significantly better than the control group,the differences were statistically significant(P<0.05);compared the recurrence and metastasis in observation group and control group after operation ,the differences were not statistical significance(P>0.05); the postoperative complication rates between observation group and control group were respectively 6% and 16%, the observation group was significantly better than the control group, the difference was statistically significant(P<0.05);the survival rate of 1,3,5 years between the observation group and the control group, had no statistically significant difference(P>0.05).Conclusion: Survival rate and recurrence rate of rectal cancer by laparoscopic and open radical resection of rectal cancer are not significant difference,but the laparoscopic radical resection of rectal cancer with rapid recovery of disease, height of minimally invasive and reliable safety, the preferred solution can be used as the surgical treatment of rectal cancer, it is worth the clinical promotion.

15 Vol. 12 (08): 28-31 [Abstract]( 532 HTML (1 KB)  PDF  (714 KB)  ( 181 )

LI Shang-hua,SHUI Sheng-quan,ZHU Xun.

Objective:To observe the effect of atorvastatin tablets combined with comfortable of jiangzhi tablets in treatment of hypertension.Method: 120 cases of patients with hypertension in hospital as study object, were divided into three group A, B, C,40 cases in each group,group A as atorvastatin treatment, group B with sxjz tablets, group C atorvastatin tablets combined comfortable of jiangzhi tablets.The changes of blood pressure, blood lipids after treatment,the clinical curative effect and clinical of three groups were observed. Result: In group C, the effective rate of 92.5% ,was higher compared with group B, C of 72.5%, 72.0%, the difference was significant(P<0.05). Group C of diastolic and systolic blood pressure of( 78.26±4.41) mm Hg,(129.58±6.25) mm Hg were lower than group A, B.In group C,TG,TC and HDL-C of blood lipid indexes were( 2.21±0.48)mmol/L,(4.38±0.71)mmol/L,and( 2.71±0.69)mmol/L,LDL-C was( 1.14±0.12)mmol/L,compared with group A and B,the differences were statistically significant(P<0.05).Conclusion: Atorvastatin tablets combined comfortable of jiangzhi tablets treatment can control hypertension and blood lipid of blood pressure patients in normal level, improve the clinical treatment effect.

15 Vol. 12 (08): 31-33 [Abstract]( 580 HTML (1 KB)  PDF  (692 KB)  ( 137 )

CHEN Hailan,CHEN Zhi-feng.

Objective:To study the efficacy of different doses of Xiyanping in treatment of acute bronchitis in children.Method:90 patients with acute bronchitis were randomly divided into the the 5 mg/(kg·d) dose group and the 10 mg/(kg·d) dose group. 45 cases in each group.The two groups were given general treatment, low dose group of Xiyanping injection intravenous drip Xiyanping injection 5 mg/(kg·d) dissolved in 100-250 mL of 5% glucose injection,
iv, qd, course of 5-7 d. High dose group of Xiyanping injection intravenous drip Xiyanping injection 10 mg/(kg·d)dissolved in 100-250 mL of 5% glucose injection,iv,qd,course of 5-7 d.Fever,cough,sputum,and lung’s clinical symptoms and signs improved situation and adverse reactions of two groups were observed.Result:The total effective rate of low doses group was 91.1%(41/45),the total effective rate of high dose group was 93.3%(42/45),there were no statistical difference(P>0.05);but the high dose of Xiyanping in cooling time of treatment group was better than the low
dose treatment group(P<0.05), the two group the incidence of adverse reaction had no significant difference(P>0.05).Conclusion:High dose and low dose treatment groups is effective in the treatment of acute bronchitis in children, can rapidly relieve symptoms andshorten the course of disease, and the safety is good. High dose treatment group has more advantages in reducing fever.

15 Vol. 12 (08): 34-36 [Abstract]( 545 HTML (1 KB)  PDF  (704 KB)  ( 200 )

LIANG Guo-hua,LAI Bao-yu,SU Chi,et al.

Objective: To probe the clinical effect observation of cerebral infarction in treatment of clopidogrel combining with fluvastatin.Method:84 patients who suffered from cerebral infarction and accepted treatment in our hospital were selected as the research objects from March 2012 to March 2014,and these patients were randomly divided into the control group,and observation group,42 patients in each group. In the control group, they were treated with the
routine curing while in the observation group, they were treated with the method of clopidogrel combining with fluvastatin. Then, the clinical effects of both groups were analyzed.Result:The overall effective rate of treatment in the observation group was 92.86%, compared that of 71.43% in the control group,the difference was statistically significance(P<0.05).Before the treatments, the blood lipid level of these two groups of patients had no evident difference(P>0.05). However,after the treatment, the observation group was evidently better than the control group,the differences had the statistically significance(P<0.05).Furthermore, according to the ADL score and the NIHSS score of these two groups, before the treatment, they had no evident differences. However, after the treatment, both these two groups of patients had evident differences and the observation group was evidently better than the control group, the difference was statistically significant (P<0.05).Conclusion:The treatment of cerebral infarction with the method of clopidogrel combining with fluvastatin is safe and can effectively restore the cranial nerve injury, which can improve the living ability of patients and improve their blood lipid level.Thus,it is worth promoting further in the clinical applications.

15 Vol. 12 (08): 36-38 [Abstract]( 539 HTML (1 KB)  PDF  (693 KB)  ( 171 )

MAO Wu-de,WU Fei,LI Meng-liang,et al.

Objective:To observe the effects of dexmedetomidine combined with pethidine alleviating shouler pain caused by laparoscopic underwent combined spinal-epidural anesthesia. Method:Sixty patients between 20 and 50 years,ASA class 1–2,scheduled for lower abdominal laparoscopy underwent combined spinal-epidural anesthesia were included in the study.Paintients were randomly assigned into three groups.Group A:patients were injected with
pethidine 0.8 mg/kg i.v.and infused with dexmedetomidine 1.0 μg/kg, and then 0.5 μg/(kg·h)after 10 minutes.Group B: patients were injected with pethidine 0.8mg/kg i.v.,normal saline was infused at the rate of dexmedetomidine in group A.Group C:patients were injected normal saline with the same dose insted of pethidine,and infused with dexmedetomidine 1.0 μg/kg, and then 0.5 μg/(kg·h)after 10 minutes.MAP,HR and shoulder pain were recorded during the operation.Result: MAP rose, HR increased after pneumoperitoneum in group B and,however kept steady group C.The incidence and severity of shoulder pain was lower in group A than in group B and in group C.Conclusion:Dexmedetomidine combined with pethidine could reduce the incidence and severity of shoulder pain caused by lower abdominal laparoscopy underwent combined spinal-epidural anesthesia.

15 Vol. 12 (08): 39-42 [Abstract]( 531 HTML (1 KB)  PDF  (744 KB)  ( 210 )

HUANG Ji-li,LU Ning,LIU Tao,et al.

Objective:To investigate the effect of noninvasive ventilation in pations with acute respiratory failure of acute exacerbation of chronic obstructive pulmonary disease.Method:The patients were divided into two groups:mild and restructuring,according to the severity of respiratory failure and results of blood gas analysis.The treatments were the application of noninvasive positive pressure ventilation mask fixation and conventional treatment.Blood gas analysis of
the arterial were checked in 0,0.5,1,24 hour in time of treatment.Result:In mild group:it had significant difference between 0 hour and 0.5,1,24 hour in time of treatment in the heart rate,respiratory frequency,pH value(P<0.05);and significant difference in PaO2,PaCO2,oxygenation index(P<0.01).In restructuring group:it had no significant difference between 0 hour and 0.5,1,24 hour in time of treatment in the heart rate,respiratory frequency,pH value (P>0.05);and significant difference in PaO2,PaCO2,oxygenation index(P<0.01).Conclusion:Noninvasive ventilation can effective treat mild respiratory failure of acute exacerbation of chronic obstructive pulmonary disease in addition to the routine treatment.

15 Vol. 12 (08): 42-44 [Abstract]( 499 HTML (1 KB)  PDF  (694 KB)  ( 303 )

ZHANG Zhi-xin.

Objective:To investigate the clinical efficacy of one-time root canal treatment of dental disease. Method:200 cases of dental patients were selected in our hospital from August 2013 to February 2014.They were randomly divided into two groups,the control group and observation group,100 cases in each group.The control group patients were treated by multiple root canal treatment, and observation group patients were treated by one-time root canal treatment.The two groups’ clinical treatment efficacy and complications were compared.Result:The observation group’s complications was 4.0%,and the control group’s complications was 26.0%,the difference was statistically significant (P<0.05);after different surgical treatments,the control group’s total effective rate was 99.0% and observation group’s total effective rate was 84.0%,the differences were statistical significance(P<0.05).Conclusion:One-time root canal in treatment of dental patients has fewer complications,shorter treatment time,better clinical treatment effect,the overall process is safe and reliable,and patients and families are more satisfied for the treatment,so it is worth to widely used in clinical practice.

15 Vol. 12 (08): 45-47 [Abstract]( 533 HTML (1 KB)  PDF  (705 KB)  ( 240 )

ZHOU Jian-xin,MO Xi-ling,YE Shao-qiang,et al.

Objective: To investigate the clinical efficacy of minimally invasive percutaneous nephrolithotomy (MPCNL) and trans-ureteroscope lithotripsy( URL) in the treatment of incarcerated upper ureteral calculi. Method:140 patients with incarcerated upper ureteral calculi were selected and divided into MPCNL group and URL group,70 cases in each group. The different efficacy of two groups were compared. Result: The operation of MPCNL group’s stone clearance rate after 3 d and 30 d were significantly higher than the URL group, the difference was statistically significant(P<0.05).The MPCNL group’s operation time, hospital stay time, gross hematuria time and the total expenses were significantly higher than URL group, the difference was statistically significant(P<0.05).The incidences of adverse reaction of two groups were not statistically significant different(P>0.05). Conclusion: In the treatment of incarcerated upper ureteral calculi, the stone clearance rate of MPCNL is higher than URL, but the surgical trauma of URL is less and the expenses of URL is lower than MPCNL.

15 Vol. 12 (08): 47-49 [Abstract]( 461 HTML (1 KB)  PDF  (705 KB)  ( 180 )

TAN Xi-xi,LIN Tao,ZHANG Li-jun,et al.

Objective:To evaluate clinical significance of transcranial Doppler ultrasonography monitoring intracranial pressure in patients with cerebral hemorrhage.Method:Sixty four patients with cerebral hemorrhage admitted by the department of neurology of Hospital from August 2014 to October 2015 were selected as research subjects, patients with cerebral hemorrhage were divided into the observation group, and 64 patients with cerebral hemorrhage admitted simultaneously were divided into the control group,respectively on two groups of patients via transcranial doppler ultrasound detecting intracranial pressure, patients in two groups were subject to tests of intracranial pressure of Doppler ultrasonography and cerebral hemodynamic parameters.Result:Patients in the experimental group patients were subject to 104 times of TCD and lumbar puncture pressure detections,and patients in the control group were subject to 40 times of detections,spectrum results suggest that average blood flow velocity and diastolic blood flow velocity decrease with the increase in intracranial pressure,and they formed inversely proportional relationship with intracranial pressure, the
change rule of systolic blood flow velocity was not obvious,and the inter-group difference was no statistically significant (P>0.05).The pulsation index and resistance index increase gradually with the increase in intracranial pressure, and the difference comparison between groups in was statistically significant(P<0.05).Conclusion:Transcranial Doppler ultrasonography detects intracranial pressure of patients with cerebral hemorrhage in noninvasive manner, and it is provided with safe and reliable testing results and others, casting guiding functions to patients.

15 Vol. 12 (08): 50-52 [Abstract]( 550 HTML (1 KB)  PDF  (694 KB)  ( 253 )

ZHOU Mei.

Objective:To analyze the impact of abnormal glucose metabolism during pregnancy on the newborn. Method: 92 patients with abnormal glucose metabolism during pregnancy were selected from January 2013 to January 2014 in our hospital, including gestational diabetes iabetes mellitus( GDM) group of 46 cases, gestational impaired glucose tolerance( GIGT) group of 46 cases,46 cases of normal glucose metabolism in the same period as the control group,the impact of abnormal glucose metabolism during pregnancy on the newborn were analyzed.Result:GDM group and GIGT group patients’ BMI ≥ 24 kg/m2,adverse pregnancy history, family history of diabetes and other risk factors were significantly higher, the differences were statistically significant(P<0.05).GDM group and GIGT group patients’neonatal asphyxia, great children, hyperbilirubinemia,and premature children were significantly higher incidence of complications than the control group, the differences were statistically significant(P<0.05).Conclusion:Abnormal
glucose metabolism has adverse effects during pregnancy on neonatal,clinical management must be strengthened in order to reduce neonatal morbidity.

15 Vol. 12 (08): 52-54 [Abstract]( 634 HTML (1 KB)  PDF  (703 KB)  ( 225 )

WU Pengtao,ZENG You-qin.

Objective:To investigate the present situation prevalence of hyperuricemia in Beijing and to analyze the risk factors.Method: 900 cases physical adults from January 2013 to December 2013 in Beijing were randomly selected, they were given routine physical and uric acid detection, the prevalence situation of hyperuricemia with questionnaire survey were observed,and the risk factors were analyzed.Result:(1)There were 80 cases with HUA among 900 people,the incidence rate was 8.89%.The incidence rate in people less than 40 years,40 years to 50 years,51 years to 60 years and more than 61 years old were respectively 0.90%,5.56%,12.96%,15.38%,the incidence rates grew following ages,the incidence rate of women was 7.31%,which was lower than 10.39% of male.(2)Gender,age,eating red meat,alcohol,BMI,high cholesterol,kidney function decline were major risk factors of hyperuricemia in Beijing(P<0.05).Conclusion:The incidence rate of hyperuricemia is high in older men,reduce red meat intake, stop drinking, reduce weight, control cholesterol reasonablely,and protect renal function are the keys for HUA prevention.

15 Vol. 12 (08): 55-57 [Abstract]( 514 HTML (1 KB)  PDF  (692 KB)  ( 177 )

ZHOU Hang,LIU Ying-chun,WANG Jun-feng.

Objective:To investigate the status of myopia of primary and middle school students in Rushan city to provide basis to make further intervention measures.Method: 1932 students in two primary and middle schools were selected by stratified cluster random sampling ,it included 1036 pupils and 896 junior school students,all of them were conducted visual inspection and questionnaire survey.Result: There were 1009 students suffer short-sightedness.The detection rate was 52.22%.Patients with mild myopia were 658,which was 65.21%;patients with mild to moderate myopia were 220,which was 21.86%;patients with high degrees of myopia were 131,which was 12.93%.The total incidence rate of pupils suffered short-sightedness was 41%;incidence rate in one to the fifth grade in primary school was respectively 24%,32%,42%,49%,60%. The total incidence rate of junior school students sufferd short-sightedness was 64%;incidence rate in six to nine grade was respectively 62%,65%,65%,69%.Conclusion:The prevalence rate of myopia is high among the investigated primary and middle school students,and increased obviously with the increase of the grate,targeted intervention measures should be taken to effective prevente the myopia.

15 Vol. 12 (08): 58-60 [Abstract]( 516 HTML (1 KB)  PDF  (682 KB)  ( 209 )

ZHANG Zhi-jun,WANG Xiao-lei.

Objective: To understand the incidence and feature in choosing drugs of hand-foot-mouth disease in the outpatient of our hospital,in order to provide a scientific basis for prevention care and control for hand-foot-mouth disease. Method:24 000 prescriptions( 8000 prescriptions/year,2000 prescriptions/quarter) of pediatric outpatient were taken randomly from January 2011 to December 2013 in our hospital, the part of them were hand-foot-mouth diseases prescription, which should be evaluated.Result: From 2011 to 2013, the number of cases in proportion to the total number cases of the outpatient in our hospital were respectively 2.95%,3.21%,and 3.70%.The number of child mortality under the age of 6 were 744 cases, which accounted for 94.30% of the total prescriptions, and children under the age of 3 accounted for 66.20%, and the morbidity peak was from May to July.In our hospital, we mostly based on antiviral treatment to treat hand-foot-mouth disease in the outpatient.Under the guidance and intervention of clinical pharmacists when secondary bacterial infection. According to the illness of children, we used reasonable combination of vitamins,immune enhancer, corticosteroids and other drugs. Conclusion: There is an upward trend in incidence of hand-footmouth diseases in the outpatient of our hospital, the disease has obvious seasonal characteristic, our hospital mostly based on antiviral treatment to treat hand-foot-mouth disease in the outpatient.Under the guidance and intervention of clinical pharmacists, we use antimicrobial agents rationally and ensure the drug safety of children.

15 Vol. 12 (08): 60-62 [Abstract]( 528 HTML (1 KB)  PDF  (680 KB)  ( 149 )

AI Hua,MA Shuxuan,QIAN Yuan,et al.

Objective: To research comprehensive nursing of superficial vein catheterization of intravenous addicts, for patients with venous addiction bring substantive quality of clinical nursing experience.Method:From February 2012 to September 2014,intravenous addiction patients hospitalized in our department were divided into case-control group and treatment group randomly.Venous addict under the improved remedy of superficial vein catheterization was set to the treatment group and venous addict under routine treatment of superficial vein catheterization was set to the case-control group,the nursing effect of two groups were compared.Result:After improving technology of venous addicts superficial vein tube insertion, compared with control group,it had the high one-time success rate of catheter,lower complication,longer the time of insertion and higher nursing satisfaction (P<0.05).Conclusion:Through an improvement of the comprehensive nursing measures in catheter nursing, flushing vascular nursing, and psychological care, to manage the problem of venous vascular addicts, can obtain good clinical effect. It is worthy to further spread and apply.

15 Vol. 12 (08): 63-65 [Abstract]( 504 HTML (1 KB)  PDF  (690 KB)  ( 175 )

LI Jing.

Objective:To investigate the effect of traditional Chinese medicine(TCM) nursing pathway on stroke depression.Method:Randomly selected 200 cases stroke depression patients from 2012 to 2013,100 cases each year,patients in 2012 were set as the control group,they received routine care only,patients in 2013 were set as observer group,they were received TCM nursing intervention on the basis of usual care. The depression score and Barthel index between the two groups after nursing intervented were compared. Result:( 1)The HAMD scores in observer group after two weeks, four weeks, eight weeks were significantly lower than the control group,the difference was statistically significant(P<0.05).(2)The Barthel index in observer groupafter nursing intervented improved more than the control group,the difference was statistically significant(P<0.05).Conclusion:The effect of TCM nursing path on stroke depression is prominent,it’sworthy of clinical application.

15 Vol. 12 (08): 66-68 [Abstract]( 443 HTML (1 KB)  PDF  (705 KB)  ( 211 )

YANG Wen-juan,MA Xiao-xia.

Objective:To observe and analyze the effects of trauma care in the preoperative and postoperative liver rupture, and to explore effective ways of care, summarize nursing experience.Method: 100 patients with traumatic rupture of the liver were selected in our hospital emergency department receives from February 2012 to May 2014 as the research object during a given surgical treatment.According to different methods of care they were randomly divided
into two treatment groups, the observation group and the control group, 50 patients in each group.The control group was treated by routine preoperative and postoperative care, the observation group was strengthen based on the usual care nursing interventions,the effect of two groups nursing care were observed ,two groups of patients with concurrent disease outbreak situation, the incidence of pain and patient satisfaction with care were compared.Result:The observation group patients after nursing intervention operation, the complications and incidence of pain were significantly lower than the control group, patients nursing satisfaction were higher than the control group, the nursing effect of two groups had statistically significant(P<0.05).Conclusion: Preoperative and postoperative care interventions in emergency liver trauma and surgical treatment of patients can reduce the incidence of pain and postoperative complication rate, effectively ensuring the quality of life of patients during surgery, with higher patients care satisfaction and has the value of clinical applications.

15 Vol. 12 (08): 68-71 [Abstract]( 512 HTML (1 KB)  PDF  (714 KB)  ( 210 )

LIANG Pei-shao,ZHENG Zhi-hong,WANG Cai-xia.

Objective:To evaluate the effect of stratified nursing model combined with drug therapy for community edlerly type 2 diabetes.Method:460 edlerly type 2 diabetes patients were came from a town as experimental group and received stratified nursing model combined with drug therapy intervention. The other 510 edlerly diabetes patients were came from other communities as control group and received conventional therapy. The blood glucose, blood fat, health behaviors and living quality were compared between the two groups. Result:After one-year intervention, the levels of fasting glucose, 2-hour postprandial blood glucose, and HbAlc in the two groups were significantly reduced( P<0.05).And those in the experimental group were significantly lower than those in the control group(P<0.05). The health behaviors( self-test blood glucose, diet control, regular exercise, weight control, taking medicine regularly), the score of living quality( healthy sense, physical symptoms, ability to work, cognitive function, ability to community participation) of the patients form the experimental group were significantly improved after one-year intervention(P<0.05). And the rules of the control group after the intervention rate improved, physical symptoms and cognitive function, the rest on improvement were not obvious( P<0.05).Conclusion:Stratified nursing model combined with drug therapy for community edlerly type 2 diabetes is effective. It’s worthy of further application and promotion in community.

15 Vol. 12 (08): 71-74 [Abstract]( 494 HTML (1 KB)  PDF  (723 KB)  ( 276 )

LI Hong,LI Yan.

Objective:To investigate the effect of health education applied in children with pneumonia. Method: 158 cases of children with pneumonia were treated in our hospital from April 2013 to January 2014 were selected and randomly divided into two groups,the control group of 78 cases,were treated routine care measures;the observation group of 80 cases,were treated health education on the basis of comparative.The efficacy of the incidence of complications
and the care satisfaction of the two groups were compared and analyzed.Result:After treatment,two groups of children were discharged, the time of pneumonia X-ray absorptiometry, body temperature normal, cough stop time, duration and so on of the observation group were better than the control group;the incidence of complications in the observation group (6.25%) was lower than the control group(19.23%),the difference was statistically significant(P<0.05);the cure rate of the observation group was also significantly higher than the control group,the difference was statistically significant
(P<0.05); the nurses attitude, responsibility, business proficiency and satisfaction of the observation group were higher than the control group,the differences were statistically significant(P<0.05).Conclusion:Health education nurses plays a supporting role to help children develop good habits, to promote children speedy recovery, to help improve the quality of life of patients and to enhance hospital patients nursing satisfaction,it’s worthy of further promotion.

15 Vol. 12 (08): 75-77 [Abstract]( 497 HTML (1 KB)  PDF  (705 KB)  ( 203 )

DUAN Hong-xia,WANG Hui,LI Yi-jing.

Objective:To observe the role and efficacy of early rehabilitation nursing in improving function recovery in patients with stroke with dysphagia.Method:66 stroke with dysphagia patients were observed,control group was given conventional treatment,observation group was given early rehabilitation nursing on the basis of control group,two groups were observed in the cure rate,Watian drinking water test, and mental state assessment survey.Result:The
cure rate in observation group was 70.59%,significantly higher than that of 21.88% in control group,the difference between two groups were statistically significant(P<0.05).Patients in two groups after treatment,Watian drinking water test had been improved,observation group compared with control group,improved more obviously(P<0.05). Mental state(SAS,SDS),self-esteem( SES) and other related life quality scores,observation group was significantly better than control group(P<0.05).Conclusion:Early rehabilitation nursing intervention can help stroke patients with dysphagia swallowing functional improvement,improve the psychological status of the patients.

15 Vol. 12 (08): 77-79 [Abstract]( 497 HTML (1 KB)  PDF  (693 KB)  ( 200 )

ZHANG Huayan.

Objective: To observe the clinical application effect of the whole nursing intervention in patients with pulmonary tuberculosis hemoptysis,so as to provide theoretical basis for clinical nursing service level.Method: 80 cases pulmonary tuberculosis hemoptysis patients in our hospital were selected,and randomly divided into two groups according to random number table: control group of 36 cases were given traditional holistic nursing, and observation group of 44 cases were given the whole nursing intervention on the basis of traditional overall care.The hemoptysis duration,hospitalization days, satisfaction of nursing, nursing quality, and quality of life in patients with anxiety and depression of emotional state of two groups of patients were observed. Result: Compared with the control group, the hemoptysis duration and hospitalization days of the observation group were significantly shorter,the satisfaction of nursing and the nursing quality were higher, the patient’s quality of life scale score was higher,the anxiety self-assessment scale scores and depression self rating scale scores were lower,the differences were statistically significant(P<0.05).Compared with the data before treatment of the observation group,the patients’ quality of life scale scores after treatment was higher,the anxiety self-assessment scale scores and depression self rating scale score were lower,the differences were statistically significant(P<0.05).Conclusion: The whole nursing intervention in patients with pulmonary tuberculosis hemoptysis can shorten the duration of hemoptysis and hospitalization time, improve the quality of life and the emotional state,improve the quality of nursing service and the satisfaction of medical staff.

15 Vol. 12 (08): 80-82 [Abstract]( 508 HTML (1 KB)  PDF  (703 KB)  ( 180 )

KANG Ying-mei.

Objective:To explore the efficacy of TCM self recipe treatment of functional dyspepsia.Method:60 cases of patients with functional dyspepsia were selected in our hospital from June 2012 to June 2013, they were randomly divided into observation group and control group, 30 cases in each group.the observation group patients were treated with TCM self recipe, the control group patients were treated with cisapride, the efficacy and symptom scores before and after treatment were compared.Result:(1)The total effective rate of observation group was 93.3%,and the total effective rate of control group was 80%,the observation group was higher than control group,the difference was statistically significant (P<0.05).(2)The symptom scores of observation group before treatment ent were( 2.79±0.15),and the symptom scores of control group before treatment were( 2.82±0.11),the difference was not statistically significant(P>0.05);the symptom scores of observation group after treatment were( 0.35±0.03) and the symptom scores of control group after treatment was( 1.58±0.24),the difference was statistically significant(P<0.05).Conclusion:TCM self recipe has a good effect in the treatment of functional dyspepsia,can significantly improve the clinical symptoms, so it is worthy to promote in clinical.

15 Vol. 12 (08): 83-86 [Abstract]( 665 HTML (1 KB)  PDF  (725 KB)  ( 390 )

WU Hua-qing,SHAO Liang,GU Sheng-qing.

Objective:To observe the effect of Chinese Traditional Formula Wenzhong Zhixie Tang on Piyang Deficiency of irritable bowel syndromes(IBS) and explore the possible mechanism. Method:100 patients were randomly divided into the treatment group and control group,50 cases in Wenzhong Zhixie Tang group and starch tablet (treatment group),50 cases in greiadine(the character was similar as the Wenzhong Zhixie Tang) and Bifidobacterium tetravaccine Tablets(Live)(positive control group).Two groups all took one month as one treatment period. Result:The use of Wenzhong Zhixie Tang treatment, abdominal pain,diarrhea symptoms,X-ray examination improved,there was significant difference with control grou(P<0.05).Conclusion:Wenzhong Zhixie Tang has remarkable effect on Pi-yang Deficiency of IBS( diarrhea type),which might be related to inhibit the excessive gastrointestinal movement,relieve the cramp of gastrointestinal tract.

15 Vol. 12 (08): 86-89 [Abstract]( 501 HTML (1 KB)  PDF  (713 KB)  ( 212 )

ZHOU Bo.

Objective: To observe the therapeutic effect of bone rheumatism mixture combined with sodium hyaluronate and other drugs for osteoarthritis of the knee. Method: 88 patients with knee osteoarthritis in our hospital were collected from February 2012 to February 2013, divided into the control group and the observation group,44 cases in each group.The control group was treated with bone rheumatism mixture decoction treatment,and the observation group was given the sodium hyaluronate injection treatment on the basis of that,the clinical efficacy of the two groups were observed. Result:The effect of observation group was better than the control group(20.45%). At the same time in the observation group, 24 hours can play well relieve effect,the differences were statistically significant(P<0.05).Conclusion:Bone rheumatism mixture combined with sodium hyaluronate injection in the treatment of knee osteoarthritis has good effect,it is worthy of clinical application.

15 Vol. 12 (08): 89-91 [Abstract]( 514 HTML (1 KB)  PDF  (693 KB)  ( 205 )

WANG Qing-hong,XU Ming-cui.

Objective:To evaluate the treatment method of cesarean section uterine incision diverticulum.Method:Our hospitai found and treated 56 patients with cutting cesarean section uterine incision diverticulum from 2007 to 2013,according to different treatment groups,the treatment group 28 cases,the control group 28 cases,the treatment group were given oral contraceptive(menstruation of mom rich grand day 5)with traditional chinese medicine therapy,the control group patients were given simple hemostatic drugs.Result:28 cases in treatment group,oral contraceptives with traditional chinese midicine therapy,menstruai period shorten the different level,effect was better than the control group.Conclusion:Oral contraceptives,combined traditional chinese medicine treatment of uterine incision diverticulum after cesarean section is effective.

15 Vol. 12 (08): 92-94 [Abstract]( 587 HTML (1 KB)  PDF  (707 KB)  ( 217 )

XIAO Zhe-fu,LI Jiang-ling,HUANG Jun-jun.

Objective:To discuss the clinical effect of water treatment for ophthalmoxerosis.Method:214 patients diagnosed with ophthalmoxerosis were chosen, they were divided randomly into two groups.Group A involved 114 patients who received water treatment together with Sodium Hyaluronate Eye Drops.Group B involved 100 patients who were only treated by Sodium Hyaluronate Eye Drops.Result:After the treatment,both two groups improved in the tests of Sit, BUT and corneal fluorescein(FL),while Group A obviously received more effective treatment than Group B.Conclusion:The combined water treatment and Sodium Hyaluronate Eye Drops usage are effective in treatment.

15 Vol. 12 (08): 94-96 [Abstract]( 453 HTML (1 KB)  PDF  (693 KB)  ( 208 )

YU Hai-xia,SHEN Yahua,ZHANG Li-na,et al.

Objective: To find out the health status of some civil servants,and provide a basis for preventive health care for the civil servants. Method: 763 cases of the civil service health outcome in our hospital in 2013 were retrospectively analyzed.Result: The results showed that the health status of the civil servants were not optimistic, only 4 of the seized items were no obvious abnormalities, physical examination pass rate was 0.53%. Anomaly detection rate in the order of 10 former is hyperuricemia, dyslipidemia, hypertension, abnormal electrocardiogram, gallbladder polyps and stones, liver dysfunction, prostate disease, fatty liver, kidney cysts, and fasting hyperglycemia. Male workers high uric acid, high cholesterol, fatty liver,and hypertension were significantly higher than that of females, the differences were statistically significant(P<0.01). Men hyperlipidemia, high blood pressure, ECG abnormalities,and prostate lesion detection rate increased with age. Women aged 50-59 years old of high blood pressure and abnormal electrocardiogram significantly increased the detection rate significantly. Conclusion: The health status of civil servants is not optimistic,high detection rate of chronic non-communicable diseases, it must to do something to eliminate the risk factors of chronic diseases, strengthen health education to improve health awareness, change lifestyle, establish the medical files, examine regularly and control of these diseases effectively.

15 Vol. 12 (08): 97-100 [Abstract]( 512 HTML (1 KB)  PDF  (714 KB)  ( 209 )

DENG Hong-lian,XIE Yan-hong,LIAO Li,et al.

Objective:To analyze the uncertainty of spectrophotometry method determination of urea in swimming pool water.Method:Urea content in swimming pool water was detected by spectrophotometry method, uncertainty of test results was analyzed based on uncertainty evaluation criteria. Result:When sampling for 10 mL,k=2,the content of the detection result of the urea was 0.746 mg/L,the uncertainty was 0.101 mg/L. Conclusion:Uncertainty of test results of urea content in the pool water are composed of a number of components, spectrophotometric determination reflects the scientific nature, is with important guiding significance for the swimming pool water quality monitoring.

15 Vol. 12 (08): 100-102 [Abstract]( 403 HTML (1 KB)  PDF  (711 KB)  ( 174 )

NIU Jia-feng,LIN Li.

Objective:To reduce the unnecessary drug-return on our work ,so as to improve clinical using medicines safely and effectively.Method:The reason of drug-return,system and methods of the drug-retrurn management were analyzed.The situation of drug-return from October 2013 to March 2014 were analyzed. Result:The situation of drug-reyurn had improved obviously from new system computer in our Hospital. The average rate of drugreturn had reduced to 3% in March 2014 from 6% in December 2013.Conclusion:The personnel of pharmacy,doctors and nurses should try hard jointly,to reduce the drug-return,to make the drug-return reasonably and canonically.

15 Vol. 12 (08): 103-106 [Abstract]( 488 HTML (1 KB)  PDF  (719 KB)  ( 210 )

ZHAO Yan-qing,CHEN Zu-yong.

Objective:To quantitatively evaluate the clinical governance in department of obstetrics and gynecology based on grey fuzzy evaluation method. Method: Various indicators in clinical governan ce of obstetrics and gynecology were expert score,then the weight value and the quantitative coefficient of evaluation system were calculated based on fuzzy mathematics method and grey system theory,in the final the comprehensive evaluation coefficient was obtained.Result:The quantitative results of the evaluation reflected the real situation of all aspects of index factors in hospital nursing objectively and reasonably. Conclusion:The establishment of evaluation system can be effective and timely to assess the governance of clinical obstetrics and Gynecology, and thus to improve, that supervised internal construction and enhance patient’s degree of satisfaction as well.

15 Vol. 12 (08): 106-109 [Abstract]( 417 HTML (1 KB)  PDF  (775 KB)  ( 289 )

WU Hua-e.

Objective:To study the clinical risk factors of neonatal intensive high blood bilirubin.Method:A total of 520 cases of neonatal intensive high blood bilirubin were selected from June 2010 to June 2011 in new pediatric ward in our hospital, the children were divided into observation group with severe high bilirubin symptoms and does not appear high bilirubin concentration in the control group with 260 cases each.By induction of integration of the two groups
of children with specific etiology,pathological mechanism,clinical symptom,therapeutic effects,such as data and information, using logistic regression model,the common causes of high blood bilirubin in such as infection,cranial hematoma,asphyxia,preterm labor were analyzed retrospectively.Result:The clinical data of observation group and control group,both the risk for age,body weight,jaundice,congenital disease,hepatitis, anemia,etc,were significant difference(P<0.05).Using logistic regression model were retrospectively analyzed and found that affects newborn children severe high blood bilirubin clinical risk factors mainly include infection,premature birth,cranial hematoma,hemolysis and other factors.Conclusion:Neonatal intensive high bilirubin levels,there are many different kinds of clinical risk factors,the main risk factors include infection,premature birth,cranial hematoma,hemolysis,etc.Determining timely and accurately grasp the clinical risk factors,to some extent,can effectively reduce the neonatal bilirubin levels,high risk,at the same time can also be for clinical diagnosis and treatment of the disease involve activities provide the beneficial reference and guidance.

15 Vol. 12 (08): 109-111 [Abstract]( 505 HTML (1 KB)  PDF  (693 KB)  ( 167 )

LI Ji-hua,JING Zhi-an,HU He-ping.

Objective:To discuss and evaluate the clinical outcomes of using buccal mucosa ucosa graft( BMG) with 1-stage reconstruction in short distal urethral strictures.Method:This retrospective study consisted of 25 patients with short distal urethral strictures underwent 1-stage urethral reconstruction using buccal mucosa graft between 2008 and 2013.Stricture was limited to the glanular urethra in all cases. Strictured urethra was resected 0.5 cm proximal to the
healthy urethra and a rectangular BMG with 3 cm length and 1.5 to 2.0 cm width( depending on the length of the defect)was rolled on a 22-Fr silicone urinary catheter.Proximal and distal edges of the BMG were anastomosed circumferentially to the healthy mucosa and meatus, respectively. Urethral catheter was removed within 12-14 days.Follow-ups included uroflowmetric parameters, voiding symptoms, and cosmesis were assessed. Result: The patients were followed for 12-60 months postoperatively( mean 32 months).Twenty-one(84.0%) patients were cured. Three patients developed stricture at proximal anastomotic site, and one patient developed early graft loss.Conclusion:Buccal mucosa graft has advantages of easy material availability, simplified preparation and strong anti-infection. Our results suggest BMG is an excellent choice in 1-stage reconstruction of distal strictures confined to the glanular urethra because the glans penis has a good blood supply, providing an efficient circumferential graft take.

15 Vol. 12 (08): 114-116 [Abstract]( 483 HTML (1 KB)  PDF  (702 KB)  ( 261 )

SONG Tao,GAO Xiao-jun,ZHU Shan,et al.

Objective:To study the value of applying the ultrasound contractibility of gallbladder test in preservation of cholecyst. Method:200 cases of gallstones or polypoid lesions of gallbladder treated by preservation of cholecyst from December 2009 to December 2011 were analyzed.200 patients consisted of 95 males and 105 females.They were measured the contractibility of gallbladder by ultrasound befor or after the surgery.Result:Including 56 patients with gallstones,43 with polypoid lesions of gallbladder,101 with both gallstones and polypoid lesions of gall bladder.According to the contractibility of gallbladder,all the patients were divided into normal group(n=120) and decreased group(n=80).The patients contractibility of gallbladder were above 30% befor surgery in normal group, and they were all treated by preservation of cholecyst,and the recurrence rate was 2.5%.The patients contractibility of gallbladder were below 30% in decreased group by preservation of cholecyst,the recurrence rate was obviously higher than the normal group(20% vs 2.5%,P<0.01).The recurrence rate in gallstones was higher than that in polypoid lesions of gallbladder,and the recurrence rate in dark bile pigment gallstone was higher than that in cholesterol gallstone.Conclusion:Ultrasound contractibility of gallbladder test is a effective method in treating gallbladder diseases,and it has a great significance clinical value in surgical selection and recovery after operation.

15 Vol. 12 (08): 117-119 [Abstract]( 489 HTML (1 KB)  PDF  (691 KB)  ( 204 )

PU Guoshi.

Objective:To investigate the rate of complications after precise gastric bypass(LRYGB) with laparoscopic,discuss the measurements of complications. Method:89 cases of patients were selected who had precised laparoscopic gastric bypass surgery treatment from June 2010 to December 2013 in our hospital.Result:9 cases(10.1%)patients accureed early postoperative complications, patients which age more than 50 years-old, combined diabetes,or with higher BMI score were the risk factors of early postoperative rative complications( OR value were respectively of 1.87,2.14,1.78,P<0.05),8 cases patients accureed late complications,age>50 years,female,and combined chronic gastrointestinal disease history were the risk factors of late postoperative complications( OR values were 1.82,1.96,1.67,P<0.05).All patients in this study were had remission after taken appropriate treatment.Conclusion:Laparoscopic gastric bypass surgery complications are not uncommon,and patients of older,combined diabetes,or with higher BMI score hare more possible to occurred early postoperative complications.Older,female,and combined chronic gastrointestinal
disease history more possible to occurred late postoperative complications.Such kinds of patients should be pay more attention in clinical work,taken appropriate treatment in the first time once occurred of complications

15 Vol. 12 (08): 120-123 [Abstract]( 520 HTML (1 KB)  PDF  (711 KB)  ( 190 )

LIU Kai.

Objective:To research the therapeutic effect of outer rear side arc incision double muscle gap approach operation on tibia platform fracture patients after lateral collapse.Method: 50 cases of tibia fracture patients of our hospital admissions were randomly extracted and were given the treatment of outer rear side arc incision double muscle gap approach surgery.Posterior tibial lateral condyle of tibia and the anterior lateral condyle were revealed through the popliteal muscle, tibialis anterior muscle and soleus muscle clearance,reduction of fracture were fixed by T type steel plate. The pain of the patient level was evaluated and the knee joint function of patients were evaluated according to the relevant provisions of Medicine After the operation.Result:Pain symptoms of patients in the observation group were improved after clinical intervention, the differences of statistical data before and after treatment were obvious. Knee joint function of patients were basically reach the normal level,recovery rate of the patients was 84%.Conclusion:Surgical treatment time of the outer rear side arc incision double muscle gap approach is short,with quick effect, high safety and less side effects.It can effectively reduce the suffering of patients and has important meaning to improve the satisfaction of patients,which is worthy of clinical promotion.

15 Vol. 12 (08): 124-125 [Abstract]( 416 HTML (1 KB)  PDF  (660 KB)  ( 131 )

LIANG Xiao-yue,ZHUANG Jun-can,WU Mu-fu,et al.

Objective:To explore the effects of pre-hospital first aid measures on the prognosis of acute myocardial infarction. Method: Used the retrospective analysis method,120 cases were randomly selected from the acute myocardial infarction patients who were treated in our hospital from June 2012 to June 2014.60 cases were treated by our pre-hospital first aid,as the first aid group;another 60 cases voluntarily came to the hospital for treatment, as the control group. Then the first aid group’s rescue and transport measures were analyzed, the mortality and satisfaction of two groups were compared.Result: The first aid group had 1 case died on the scene for 1.67%,3 cases died after admission for 5%, the total mortality was 6.67%,higher than the control group of 13.33%;and it’s patients’satisfaction was 98.33%,significantly higher than the latter 70%, the differences were statistically significant( P<0.05).Conclusion:Pre-hospital first aid is very necessary for patients with acute myocardial infarction, which can improve the rescue success rate, ensure patients’ health and reduce mortality.

15 Vol. 12 (08): 128-131 [Abstract]( 524 HTML (1 KB)  PDF  (722 KB)  ( 224 )

LI Cai-hong.

Objective:To explore a variety of typical and atypical clinical symptoms and signs of ultrasonic diagnosis of digestive tract perforation clinical analysis.Method:76 cases of patients with digestive tract perforation were reviewed from June 2005 to June 2014, which was confirmed by surgery ultrasound image data, in combination with X-ray and clinical treatment were analyzed. Result:76 cases of digestive tract perforation ultrasound diagnosis were consistent  with surgery diagnosis. By the ultrasonic positioning of the 13 cases of digestive tract perforation were consistent with the parts in operation. The x-ray examination of 65 cases with typical clinical symptoms of digestive tract perforation were consistent with the parts of ultrasound diagnosis. 11 cases of atypical clinical symptoms of digestive tract perforation were prompted by ultrasound that there was a small amount of gas in abdominal cavity. Suggested that after clinical pressurized air and reviewed by the X-ray was positive and confirmed.Conclusion:The digestive tract perforation ultrasound diagnosis coincidence rate is high. Especially for the early and atypical clinical symptoms of digestive tract perforation is superior to the X-ray diagnosis.And makes up for the defect of the X-ray that can't locate. For suspected cases still can guide clinical further lines of other corresponding examination and confirmed. To avoid missed diagnosis and misdiagnosis in clinical has important guiding significance.

15 Vol. 12 (08): 131-134 [Abstract]( 426 HTML (1 KB)  PDF  (699 KB)  ( 157 )

YU Hua,HUANG Zuo-gui,LI Xiao-hua,et al.

Objective:To investigate the prognosis of acute myocardial infarction malignant ventricular arrhythmia patients.Method: 45 patients of acute myocardial infarction malignant ventricular arrhythmia were selected as the observation group,and 45 patients of coronary heart disease no acute myocardial infarction malignant ventricular arrhythmia were selected,all of them were treated by electric defibrillator,electroconversion,implanted cardioverterdefibrillator and medicine cure, results of the two group were compared and analyzed. Result:24 hour cure succeed ratio of two groups were respectively 77.77%,100%.In two weeks survival ratio of two groups were respectively 66.66%,88.88%.In 1 year survival ratio of two groups were respectively 57.77%,84.44%.Compared the two groups,the difference was statistically significant(P<0.05).Conclusion:The survival ratio of malignant ventricular arrhythmia patients were lower and the mortality were very high,for this kind patient,electric defibrillator,electroconversion,and medicine cure must be used at once to improve prognosis and reduce mortality.

15 Vol. 12 (08): 135-137 [Abstract]( 605 HTML (1 KB)  PDF  (694 KB)  ( 242 )

LU Qi-zhi.

Objective:To study clinical observation of hysteroscopy following intrauterine membrane cutting treatment intractable dysfunctional uterine bleeding( DUB) function.Method:From June 2012 to June 2014,hysteroscopic transcervical resection of endometrium( transcervical resection of endometrium, TCRE) treatment was repeated drug treatment of bleeding in 63 cases, preoperative diagnostic curettage of endometrium pathology for 38 cases of simple hyperplasia, 18 cases of polypoid hyperplasia, gland tumor like hyperplasia in 7 cases. First, 3, and 6 months follow-up after operation.Result:63 cases of TCRE surgery were completed smoothly.No uterine perforation,water intoxication and pelvic viscera complications such as electrical injury.All completed six months follow-up,amenorrhea 39(61.9%), menstruation was a small amount of 15 cases(23.8%),menstruation normal 9 cases( 14.3%).After six months of FSH, LH, E2, P value, and there was no significant difference before surgery(P>0.05).Conclusion:TCRE treatment-resistant minimally invasive technology function,have a safe and effective, does not affect ovarian endocrine
function,etc.

15 Vol. 12 (08): 137-139 [Abstract]( 390 HTML (1 KB)  PDF  (694 KB)  ( 202 )

RU Min-hui,LUO Jian-ying,OUYANG Yu-xia,et al.

Objective: To explore the clinical curative effect and nursing of laparoscopy combined with different doses of mifepristone in treating endometriosis. Method: 48 patients with endometriosis were collected in our hospital from June 2013 to June 2014,and randomly divided into observation group and control group,24 cases in each group, the control group in laparoscopic operation with large doses of mifepristone, and the observation group with low doses.At the same time, two groups of patients were given corresponding nursing measures in operation.After six months treatment,the effects of two groups patients were compared. Result: The observation group clinical efficiency was 54.17%, significant efficiency was 37.50% and non efficiency was 4.17% and the control group was respectively 45.38%,33.33% and 4.17%,the difference was statistically significant(P<0.05). In the postoperative recurrence rate, the observation group was 4.17% lower than that in the control group of 16.67%,the difference was statistically significant(P<0.05).
Conclusion: Laparoscopic combined with small dose of mifepristone has obvious clinical efficacy.At the same time in the course of treatment with comprehensive nursing measures, so as to further improve the use of small dose of mifepristone in safety. The therapy is worth further promotion.

15 Vol. 12 (08): 140-142 [Abstract]( 552 HTML (1 KB)  PDF  (693 KB)  ( 366 )

YANG Zhen-ling,HUANG Qi-ren.

Objective:To explore the clinical treatment of senile gastrointestinal bleeding and the effect. Method: 58 cases of elderly patients with gastrointestinal bleeding randomly divided into two groups, each group of 29 cases. Control group were treated by endoscopic injection of 1:10 000 epinephrine treatment,observation group of patients with endoscopic injection curing agent treatment,compared two groups of hemostatic rate, length of hospital stay,and bleeding rate, incidence of complications and mortality rate. Result:Two groups of patients in hospital time, success rate of hemostasis and bleeding rate, incidence of complications and mortality were significantly better than the control group, the difference is statistically significant( P<0.05).Conclusion:Endoscopic injection of hardener treatment of the senile gastrointestinal bleeding effect is remarkable, is beneficial to reduce the bleeding rate again, is worth popularization and application in clinic.

15 Vol. 12 (08): 142-144 [Abstract]( 542 HTML (1 KB)  PDF  (694 KB)  ( 150 )

HUANG Xiao-ying.

Objective:To explore the application value of color Doppler ultrasonography in the prenatal diagnosis of placenta previa in blood vessel.Method:Maternal doppler ultrasonography data in our hospital from 2011 to 2013 were selected and analyzed.The occurrence of vasa previa was analyzed and further diagnosised combine with the clinical operation.Result:There were 28 cases of vasa previa occurred, the incidence was 0.053% in 53186 cases of pregnant  women in pregnancy test.Prenatal ultrasound diagnosed 25 cases, the positive rate was 89.29%, 3 cases were missed  diagnosis. Color doppler ultrasonography in cervical sagittal cervical internal tubular vessels across the top,visible placental cord entrance section, the umbilical cord blood vessels near or across the endocervix,the placental edge was placenta cord entrance.3 cases of missed diagnosis for patients were given ultrasound examination for type B in late pregnancy,vaginal delivery,and fetal death. The merger of velamentous placenta were 17 cases,with vice placenta were 7 cases, 4 cases were complicated with placenta extract.Conclusion:Antenatal examination may be useful for diagnosis of placental vasa previa by color Doppler ultrasound, and to achieve a higher diagnosis rate, and can be used as early diagnostic method.

15 Vol. 12 (08): 144-146 [Abstract]( 516 HTML (1 KB)  PDF  (689 KB)  ( 297 )

LI Huan-xiong,HE Li-hua,DAI Xu-hui.

Objective:To compare the clinical effect and safety of minimally invasive percutaneous nephrolithotomy(MPCNL) and ureteroscopy lithotripsy(URL) for upper ureteral calculi.Method:The clinical data of patients with upper ureteral calculi including MPCNL group and URL group were analyzed,respectively.The calculi clearance rate,operative time,intraoperative blood loss,length of hospital stay and incidence of complications were compared.Result:No significant differences of clinical data were observed between the MPCNL group and URL group before the treatment.After treatment, the calculi clearance rates of MPCNL group were significantly superior to the URL group(P<0.05).However,the operative time,intraoperative blood loss and length of hospital stay of URL group were significantly less than MPCNL group(P<0.05).Besides,there was no significant difference of incidence of complications between the two groups( P>0.05).Conclusion:The best treatment schedule should be determined according to the patients conditions, surgical indications and patients’ thoughts to achieve good clinical effect and patients’ satisfactory.

15 Vol. 12 (08): 147-149 [Abstract]( 521 HTML (1 KB)  PDF  (725 KB)  ( 261 )

GUO Ya-nan, MA Yu-ping.

This article reviews the post competency for clinical nurses at home and abroad from the origin and concept of competency,composition of the nurse competency and nurse competency evaluation.It summarizes the characteristics of competence and analyzes the shortage of the nurse competency concept and the advantages and disadvantages of the nurse post competency assessment tools. Pointed out: The research about nurse competency in China
is not yet mature, there is a lack of objective, scientific and effective nurse ability measuring tool.assessment based on national conditions in different level of the nurse post competency is the direction in the future in clinical nurse post competency.

15 Vol. 12 (08): 150-153 [Abstract]( 578 HTML (1 KB)  PDF  (713 KB)  ( 536 )

LU He-zhen,LIANG Wen-hong.

Th17 cells and Treg cells are new subsets of CD4+ T-lymphocytes, who are different from Th1 and Th2 in the process of development and differentiation, and can also regulate each other in function. The Th17 cells mainly mediates the occurrence of the body’s inflammatory response and autoimmune diseases, while the Treg cells play an important role in inhibition of immune function and maintenance of immune steady state. Also there is a relationship of mutual transformation between them. The current studys find that Th17 and Treg cells are involed in inflammatory diseases, autoimmune diseases and tumor development and also in oral diseases. This article makes a review on the function and regulation of Th17 cells and Treg cells and relations between them and oral mucosal diseases.

15 Vol. 12 (08): 153-156 [Abstract]( 412 HTML (1 KB)  PDF  (715 KB)  ( 250 )

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