-
ZHANG Jian-lei，WANG Zhao-hui，LI Guo-fei，et al.
Objective：To investigate the efficiency of midazolam in treatment of status epilepticus. Method：52 patients with status epilepticus（from January 2012 to January 2014）were randomly divided into control group and midazolam group，the former were given conventional treatment and diazepam，while midazolam group were given conventional treatment and midazolam. Result：The total effective rate of midazolam group was 92.3%；the total effective rate of the control group was 80.7%，the difference was statistically significant（P<0.05）.Midazolam group‘s control time was （36.5±4.73）min，control group’s control time was（47.9±5.8）min，the difference was statistically significant（P<0.05）.There were one case of pulmonary infection，one case of hypotension in midazolam group， while two cases of pulmonary infection，one case of hypotension in control group，all these cases were relieved after symptomatic treatment.The difference was not statistically significant in adverse reactions between two groups（P>0.05）. Conclusion：Midazolam is safe， effective and rapid onset in treatment of status epilepticus.
2014 Vol. 11 (26): 1-3 [Abstract]（
881
）
HTML
(1 KB)
PDF
(1008 KB)
(
543
)
-
JIN Xia，MA Jing-ru.
Objective：To discuss the dynamic changes of BNP in the patients of AMI and the clinical significance of the early diagnosis of AMI. Method：Plasma BNP in 22 SA cases，24 UA cases，20 healthy cases were tested and the plasma BNP of 41 AMI cases also were tested in 2，4，6 and 24 h after the onset of AMI.Result：BNP level of AMI group and UA group were obviously higher than that of SA group（P<0.01）.Plasma BNP level in 4，6，24 h after onset of AMI were obviously higher than that of UA group（P<0.01）.4 h and 6 h after AMI onset the surface area under ROC curve were 0.819 and 0.898. Conclusion：AMI patients have an increased plasma BNP level obviously 2 hours after the onset of AMI，and the BNP level increases significantly with the extension of tine. 4 h and 6 h after the onset of AMI the plasma BNP level have good diagnostic value for AMI.
2014 Vol. 11 (26): 3-6 [Abstract]（
728
）
HTML
(1 KB)
PDF
(1366 KB)
(
269
)
-
Objective：To investigate the influence of different single-lung ventilation on respiratory function and sevoflurane FA/FI.Method：45 patients underwent thoracotomy lobectomy and one-lung ventilation（OLV）in our hospital from January 2012 to January 2014 were selected，they were divided into the group A，B and C according to the random number table method，15 cases in each group.The group A underwent volume-controlled ventilation，the group B underwent pressure-controlled ventilation，the group C received small tidal volume and PEEP ventilation.The changes in vital signs and airway pressure after 10 min total lung ventilation（TLV）and after 20，45，70 min OLV of the three groups were compared.The three groups were received inhalation of 1.5% sevoflurane 20 min when OLV 20 min，and the FA/FI of the 3 groups were compared.Result：After OLV，T2-T4，the peak airway pressure of 3 groups were increased， but the group A and B were significantly increased（P<0.05），and lung compliance of the 3 groups were reduced，but the group A and group C were significantly reduced（P<0.05），intrapulmonary shunt fraction of the 3 groups were significantly increased，but the group C was significantly lower than group A and group B（P<0.05），arterial oxygen tension were significantly decreased（P<0.05），but there was no significant difference between groups（P>0.05）.In the early 8 min，the FA/FI of group B was higher than group C，over time，the three groups FA/FI converge.Conclusion： Pressure-controlled ventilation in single-lung ventilation status can improve the lung compliance，but it has no significant effect for narcotic drugs FA/FI.
2014 Vol. 11 (26): 7-10 [Abstract]（
685
）
HTML
(1 KB)
PDF
(1111 KB)
(
404
)
-
YANG Juan，TAN Min，HU Qun-li.
Objective：To study bone metabolism index changes of postmenopausal patients with type 2 diabetic nephropathy combined osteoporosis. Method：based on bone mineral density was divided into 36 cases of type 2 diabetic nephropathy and osteoporosis，34 cases of type 2 diabetic nephropathy and normal bone mineral density ，and 33 cases of type 2 diabetic mellitus were selected. Calcium，phosphorus，ALP，PTH，PINP，and β-CTX and 25-OHD of three groups were determined.Result：ALP，PTH，PINP and β-CTX in diabetic nephropathy osteoporosis group and bone mass normal group were significantly higher than those in diabetic group（P<0.05 or P<0.01）.25-OHD in diabetic nephropathy osteoporosis group and bone mass normal group were lower than that in diabetes group（P<0.05 or P<0.01）. There were no statistical difference in blood phosphorus and blood calcium among groups.Conclusion：ALP and PTH in patients with type 2 diabetic nephropathy are elevate，PINP and β-CTX are sensitive indexs of osteoporosis.
2014 Vol. 11 (26): 10-12 [Abstract]（
555
）
HTML
(1 KB)
PDF
(988 KB)
(
172
)
-
FAN Xiao-chen.
Objective：To investigate characteristics，surgical methods and initial efficacy of the anti-rotation type proximal nail（proximal femoral nail antirotation，PFNA）in treatment of elderly patients with unstable femoral intertrochanteric fracture.Method：26 elderly patients with unstable femoral intertrochanteric fracture who treated with PFNA from March 2008 to December 2012 were selected，11 cases were male，15 cases were female，65-97 years old， the mean age was 78.2 years.According to AO classification，A2 type was 16 case，A3 was 10 case.After admission，17 patients were treated with skin traction，9 patients were treated with skeletal traction.Patients underwent surgery after admission 2-4 d，underwent traction manipulation by lower limb traction bed of orthopaedics in the surgery，PFNA was placed into small incision，in surgery couldn’t be exposed fracture.Result：In 26 patients，the average operation time was 55 min（40-110 min），the average amount of bleeding was 80 mL（30-200 mL），1 patient transferred to medical
treatment because of lung infection and 2 cases combined deep venous thrombosis（DVT），the remaining patients were discharged from the hospital.Followed up for 5-48 months，an average of 20 months，partial weight-bearing was 2 weeks，the full weight-bearing walking time was 4 weeks，fracture healing time was 10 weeks，patients were no incision nfection，deep vein thrombosis，internal fixation loosening and hip varus complications.According to the Harris hip function score：excellent in 18 cases，good in 4 cases，general in 2 cases，poor in 1 case.the excellent and good rate was 84.6%.Conclusion：PFNA combined with traction bed treatment of unstable intertrochanteric femoral fractures has less trauma，simple operation，less complications，internal fixation and other advantages，is worthy of clinical application.
2014 Vol. 11 (26): 13-16 [Abstract]（
566
）
HTML
(1 KB)
PDF
(1407 KB)
(
302
)
-
TENG Xin，YU Hai-tao，WANG Hao.
Objective：To evaluate the clinical application of color doppler ultrasound and CT in the diagnosis of cryptorchidism and its malignant transformation，to provide effective，economic and non-invasive way for qualitative diagnosis.Method：Forty-five patients with 51 cryptorchidism were examined by ultrasound and CT in recent years. Their imageological examinations were compared with surgical and pathological results respectively. Result：In 51 cryptorchidism ，45 cryptorchidism were detected by ultrasound，with the detection rate of 88.2%. Among those cases，4 of 5 malignant transformations were detected by ultrasound（detection rate 80.0%）. In contrast，43 out of 51 cryptorchidism were detected by CT examination（detection rate 84.3%），of which 5 malignant cases were detected by CT with the accuracy rate of 100%. Among total 14 celiac cryptorchidism cases，11 cases（78.5%）were detected by ultrason examinations，while 13 cases（92.8%）were detected by CT scan. There was no significant difference between ultrasound and CT examination as for the detection rate in the diagnosis of cryptorchidism and its progression（P>0.05）. Conclusion：Compared with CT，the color doppler ultrasound examination are high accuracy，easier to check，low-cost and non-invasive，therefore it is the preferred method in the diagnosis of cryptorchidism. However，in order to improve the diagnosis rate，ultrasound examination should be recommended to cooperate with CT for celiac cryptorchidism patients or patients with cryptorchidism malignant transformation.
2014 Vol. 11 (26): 16-18 [Abstract]（
619
）
HTML
(1 KB)
PDF
(982 KB)
(
170
)
-
ZHOU Man-ying，ZHENG Ying-ying，WANG Wei-qi，et al.
Objective：To explore the anesthetic efficacy of lidocaine block anesthesia mixed articaine infiltration anesthesia on the mandibular molar extraction.Method：60 patients were randomly divided into three groups，each group had 20 cases. The 1st group was injected lidocaine 5 mL with block anesthesia，the 2nd group was injected articaine 1.7 Ml with infiltration anesthesia，the 3rd group was given mixed anesthesia，the 1st group + the 2nd group.Result：The anesthesia effect of the 3rd group was better than the other two groups （P<0.05）.Conclusion：The application of mixed anesthesia on the mandibular molar extraction can get good effect， it is fit for clinical use.
2014 Vol. 11 (26): 19-20 [Abstract]（
552
）
HTML
(1 KB)
PDF
(955 KB)
(
189
)
-
LI Wei-qian，KONG Qing-yan，LIU Xia.
Objective：To analyze the clinical application value of liquid-based cytology test for cervical cancer screening.Method：450 females received cervical cancer screening in our hospital from February 2012 to February 2014 were selected.The patients received two kinds of examination ways，and the patients were divided into two groups according to examination ways.The control group received pap smear method，and the research group received liquid-based cytology test.The positive condition of two groups was analyzed，and the biopsy status was compared and analyzed under colposcope.Result：The satisfactory rate and the positive rate of the research group was 92.89%（418/450）and 49.56%（223/450），they were significantly higher than 70.00%（315/450） and 24.22%（109/450） of the control group， the differences were statistically significant（P<0.05）.And the coincidence rate of CINⅡ-Ⅲ level in the research group was 23.77%（53/223），it was significantly higher than 3.67%（4/109）of the control group，the difference was statistically significant（P<0.05）.Conclusion：Liquid-based cytology test for cervical cancer screening not only has high application value，but also can significantly improve the clinical detection rate of patients with cervical cancer，which is worthy of clinical promotion and application.
2014 Vol. 11 (26): 21-23 [Abstract]（
561
）
HTML
(1 KB)
PDF
(982 KB)
(
305
)
