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The Changes of Bone Metabolism Index in Postmenopausal Patients with Type 2 Diabetic Nephropathy |
The Provincial Hospital Affliated to Anhui Medical University |
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Abstract Objective:To study bone metabolism index changes of postmenopausal patients with type 2 diabetic nephropathy combined osteoporosis. Method:based on bone mineral density was divided into 36 cases of type 2 diabetic nephropathy and osteoporosis,34 cases of type 2 diabetic nephropathy and normal bone mineral density ,and 33 cases of type 2 diabetic mellitus were selected. Calcium,phosphorus,ALP,PTH,PINP,and β-CTX and 25-OHD of three groups were determined.Result:ALP,PTH,PINP and β-CTX in diabetic nephropathy osteoporosis group and bone mass normal group were significantly higher than those in diabetic group(P<0.05 or P<0.01).25-OHD in diabetic nephropathy osteoporosis group and bone mass normal group were lower than that in diabetes group(P<0.05 or P<0.01). There were no statistical difference in blood phosphorus and blood calcium among groups.Conclusion:ALP and PTH in patients with type 2 diabetic nephropathy are elevate,PINP and β-CTX are sensitive indexs of osteoporosis.
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