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中国医学创新

2015 Vol.12,No.18

Published 2016-06-25

ZHAN Xiao-dong,LI Chao-pin,XI Yi-long.

Objective:To compare several extraction methods of one head mite mitochondrial genome.Method:According to reference method,the total DNA of one head mite were extracted by methods of Phenol chloroform method,Chelex-100 method and Proteinase K method.Result:Phenol chloroform method failed to amplify the purpose gene,but Chelex-100 method and Proteinase K method were successfully amplified out of the purpose gene.Conclusion:Chelex-100 method and Proteinase K method can be used in one head mite mitochondrial genes extraction,the large amount of template can be obtained with the Chelex-100 method,but its extraction efficiency is less than the Proteinase K method.

2015 Vol. 12 (18): 1-4 [Abstract]( 588 HTML (1 KB)  PDF  (754 KB)  ( 232 )

WU Wang-xi,CHEN Zhu-su,ZHOU Lei,et al.

Objective:To evaluate simultaneous apical surgery with crown lengthening for severe periapical diseases in short-term.Method:The total of 6 patients from Guangdong Provincial Stomatological Hospital from Sep 2013 to Oct 2014,6 cases with 23 roots with severe periapical lesions were treated using simultaneous apical surgery with crown lengthening for resecting apical lesion,trimming gingival margin,shaping alveolar,improving clinical crown height at the same time,provisional restorations before and after surgeries,then final restorations 3 months after surgeries.Evaluation of bone healing by
CBCT,soft tissue healing by PES.Result:Periapical defect filled with new bone,gingival margins and restorations were stable 6 months after surgeries.Conclusion:Simultaneous apical surgery and crown lengthening is a valid treatment to severe periapical diseases. 

2015 Vol. 12 (18): 4-7 [Abstract]( 485 HTML (1 KB)  PDF  (789 KB)  ( 247 )

CHEN Feng,PENG Mu-li,LIANG Guo-hua,et al.

Objective:To explore the efficacy of acute blood pressure regulation in different types cerebral infarction prognosis.Method:162 patients with acute cerebral infarction were randomly divided into the control group(n=95) and the intervention group(n= 67).The control group patients patients were treated with routine use of aspirin,calcium antagonists,and supplemented citicoline be symptomatic and supportive treatment.The intervention group were treated with drugs for lowering blood pressure on the basis of the control group.Decreased blood pressure in 160/100 mm Hg in 1 day after admission.The NIHSS
score,Barthel Index score and modified Rankin scores were compared at admission,the first week after treatment,six months after treatment and and 1 year after treatment between the two groups.Result:The Barthel Index score at the first week after treatment(46.3±12.8) points vs( 49.1±13.3) points in the intervention group were significantly lower than the control group (P<0.05).The NIHSS,Barthel Index score and modified Rankin score at six months after treatment and 1 year after treatment in the intervention group were significantly lower than the same period of the control group(P<0.05 or P<0.01).The Barthel Index scores at the first week after treatment of TACI,PACI,POCI type were significantly lower than those of the control group (P<0.05).The modified Rankin score at the first week after treatment of TACI type was significantly higher than the control group (P<0.05).The Barthel Index scores at six months after treatment of LACI,TACI,PACI,POCI in the intervention group were significantly lower than the same period of the control group(P<0.05 or P<0.01).The NIHSS score at six months after treatment of LACI,TACI,PACI,POCI in the intervention group were significantly higher than the control group(P<0.05 or P<0.01).Conclusion:The efficacy of early Antihypertensive treat for acute cerebral infarction prognosis are poor.

2015 Vol. 12 (18): 8-11 [Abstract]( 612 HTML (1 KB)  PDF  (742 KB)  ( 295 )

BIAN Yan-hui,WANG Qing-xin.

Objective:To learn the level of general self-efficacy and its influencing factors in ovarian cancer patients undergoing chemotherapy and explore the possible countermeasures to improve self-efficacy.Method:82 cases of ovarian cancer patients undergoing chemotherapy from a certain hospital of Shanxi selected as research objects by using convenience sampling method were investigated by a general patient questionnaire and the general self-efficacy scale,then their general self-efficacy levels and influencing factors were analyzed.Result:Mean score of general self-efficacy of 82 cases of ovarian cancer patients
undergoing chemotherapy was( 23.40±6.46),of which only 17 cases(20.73%) showed a high level of self-efficacy.The level of self-efficacy of patients with different age,permanent residence,education level,family income,clinical stage of disease,course of the disease,chemotherapy times was statistically significant.Conclusion:Ovarian cancer patients undergoing chemotherapy had a low level of General Self-efficacy,so when develop nursing interventions and do patient follow-up,nurses should assess the level of general self-efficacy in patients,also should looking for possible influencing factors and supply appropriate interventions to improve self-efficacy.

2015 Vol. 12 (18): 11-14 [Abstract]( 572 HTML (1 KB)  PDF  (737 KB)  ( 396 )

ZHANG Shan-shan,DU Zhen-sheng,CHEN Feng,et al.

Objective:To observe the the effect of comprehensive rehabilitation on neural micro-angiogenesis in rat with sciatic nerve compression.Method:According to the rat model of sciatic nerve compression designed by Mackinnon,forty male SD rats were chosen and randomly divided into 4 groups(n=10):group A,group B,group C,and group D.After 2 weeks,compression were removed in all 4 groups,and no treatment was given in group A,rehabilitation training in group B,electroacupuncture in group C,electroacupuncture combined with rehabilitation training in group D.At 3 weeks after treatment,the sciatic nerve function index( SFI),and the expression of CD34,VEGF in the compression sciatic nerve of rats were measured.Result:The SFI recovery rate of groups B,C,and D were significantly higher than that of group A(P<0.05),and that of group D was significantly higher than that of groups B and C(P<0.05).The expression of CD34 and VEGF in the compression sciatic nerve of groups B,C,and D were significantly higher than that of group A(P<0.05),and that of group D was significantly higher than that of groups B and C(P<0.05).Conclusion:Comprehensive rehabilitation can improve neural micro-angiogenesis in rat with sciatic nerve compression,thereby it can promote the nerve regeneration and functional recovery.

2015 Vol. 12 (18): 15-17 [Abstract]( 521 HTML (1 KB)  PDF  (720 KB)  ( 260 )

WANG Kang-chun,LI Man-yuan,YU Xiao-teng,et al.

Objective:To study the tigecycline,polymyxin B and cefoperazone sulbactam motionless bacilli in vitro antibacterial activity against multi drug resistant Bauman acinetobacter,to provide the basis for clinical rational drug use.Method:The clinical microbiology laboratory bacteria cultures of drug sensitivity test specimens were selected in our hospital from January 2013 to June 2014,the results identified by the multi drug resistance of 50 strains of Bauman Acinetobacter,drug sensitivity disk diffusion method were used to tigecycline,polymyxin and cefoperazone sulbactam for in vitro drug sensitivity test. Result:Tigecycline against multi drug resistant acinetobacter keep Bauman sensitivity of 100%,polymyxin B and moderate sensitivity was 67%,resistant to cefoperazone sulbactam rate was 73%.Conclusion:Tigecycline and polymyxin against multi drug resistant Bauman acinetobacter have high antibacterial activity,is one of the best drug bacillus for the treatment of multi drug resistant acinetobacter Bauman.

2015 Vol. 12 (18): 17-20 [Abstract]( 629 HTML (1 KB)  PDF  (730 KB)  ( 270 )

YANG Tan.

Objective:To observe the effect of Cinnamomum cassia( CE) on LTP in hippocampal CA1 area of diabetic rats induced by streptozotocin(STZ).Method:27 SD rats were randomly divided into control group,diabetes mellitus(DM)group and CE group.The model of diabetic rats were induced by a single injection of streptozotocin at a dose of 65 mg/kg.Rats in the CE group were given 5 g/kg CE by intragastric gavage every day.Electrophysiological method was used to observe the LTP in hippocampal CA1 area,Levels of N- methyl-D-aspartate receptor subtype 2B( NR2B) in the hippocampal tissue were analyzed by western blot.Result:In the electrophysiological experiments,population spike(PS) amplitude significantly decreased in the DM group versus control.CE treatment could restore PS amplitude and significantly increase the expression levels of NR2B in the hippocampus of diabetic rats.Conclusion:CE can improve LTP in the hippocampal CA1 of diabetic rats and this effect could be attributed to the up-regulation expression of NR2B.

2015 Vol. 12 (18): 20-22 [Abstract]( 633 HTML (1 KB)  PDF  (749 KB)  ( 192 )

GUO Zheng-dong,LIANG Zhi,LIN Hai-bo,et al.

Objective:To analyze the clinical application value of bFGF combined acasintm on treating residual burn wounds through comparative observation the clinical effect on treating residual burn wounds.Method:64 patients with residual burn wound who were treated in our hospital from December 2013 to December 2014 were selected as the research objects. Experimental group used bFGF combined Acasintm,control group took routine treatment of residual burn wounds,the two groups’ clinical efficacy,wound healing rate and bacterial clearance rate were compared.Result:There were 64 residual wound 62 effective in 64 cases of experimental group,the total effective rate was 96.87%.There were 54 effective in 64 cases of residual burn wounds in control group,the total effective rate was 74.37%,the difference between two groups’ total efficiency were obvious,with statistical significance(P<0.05).There were no obvious difference between two groups’ wound residual wounds after 4 d treatment compared with the shrinkage rate of the treatment of 10,16,22 d and residual wounds after retraction,with statistical significance(P<<0.05).The experimental group’s therapy healing time was( 18.26±3.47)d,the bacterial eradication rate was 78%;wound healing time of control group was( 29.35±4.86)d,the bacterial eradication rate was 40%,two groups of healing time and the bacterial clearance rate had significant differences(P<0.05).Conclusion:bFGF combined Acasintm can shorten the healing time on treating residual burn wounds,its antimicrobial effect is obvious and can promote wound healing as well as effect obviously which has certain clinical significance.

2015 Vol. 12 (18): 23-25 [Abstract]( 441 HTML (1 KB)  PDF  (718 KB)  ( 179 )

SUN An-ling,WANG Xin,LIANG Qian,et al.

Objective:To explore the effect of Dexmedetomidine on onset time and reaction time of Vecuronium target controlled infusion.Method:60 cases of colon cancer patients undergoing general anesthesia were selected in our hospital from March 2013 to June 2014,they were randomly divided into the control group and the study group,each group had 30 cases.Heart rate (HR),systolic blood pressure(SBP),diastolic blood pressure(DBP) were compared between the two groups before anesthesia (T0),after continuous infusion Dex 30 min( T1),60 min(T2),at the end of surgery(T3).Vecuronium onset time,clinical reaction time,target concentration,residual NMB after extubation,and respiratory depression were compared between the two groups.Result:In HR,SBP,DBP,the study group were significantly lower than the control group(P<0.01) at T1 period and after each period.In the onset time,the study group had no significant difference with the control group(P>0.05),but in the clinical aging time and vecuronium target concentration,the study group was lower than the control group( P<0.01),in the incidence of residual NMB,the study group was significantly lower than the control group(P<0.01),but in respiratory depression after extubation,the two groups had no significant difference(P>0.05).Conclusion:Dexmedetomidine does not affect vecuronium onset time but will significantly extend the clinical reaction time and reduce the dosage of vecuronium in a certain extent.

2015 Vol. 12 (18): 26-28 [Abstract]( 488 HTML (1 KB)  PDF  (707 KB)  ( 182 )

HUANG Jie-yuan,MO Xiong,GUO Wei-tao.

Objective:To explore the clinical effect and feasibility analysis of the anteroposterior approach with the patient lying in the lateral position with the pedicle screw implantation in the spine surgery.Method:30 cases were chosen,approached with the patients lying in the lateral position with the pedicle screw implantation.Patients were regularly followed up and visited.The changes of every indicator of patients’ bodies were compared.Result:All cases were followed up for 12 to 24 months.The average spinal canal occupation ratio was( 48.15±5.21)% and the average segental Cobb angle was(34.3±2.8)°,the average anterior vertebral height was( 56.16±11.67)%.But in the last time follow-up after surgery,the indicators which were examined were restored and achieved to a satisfactory results.After resection of the vertebral body,the average segmental Cobbangle was(3.4±1.1)° post-operatively,and neurology function was restored 1-2 grades in 29 cases except 1 case was not restored defined by ASIA criteria.Conclusion:Treatment of thoracolumbar burst fracture by ananteroposterior approach with the patient lying in the lateral position can result in good clinical effectiveness and it is worth promoting in the clinic.

2015 Vol. 12 (18): 29-31 [Abstract]( 522 HTML (1 KB)  PDF  (719 KB)  ( 174 )

LIN Qi-ming,LAO Guo-rong,WANG Jian-hua.

Objective:To explore and analyze the value of multilayer spiral CT 3D reconstruction technique in the application of ankle fracture diagnosis and preoperative evaluation.Method:Multilayer spiral CT three-dimensional reconstruction technique and X-ray DR were given to the patients with ankle fractures for preoperative examination,classification and reexamination after surgery.Result:Comparing the preoperative DR parting with intraoperative result,the Kappa value in the lines of PAB,SAB,PER and SER was good.Compared with the intraoperative result,the consistency of results,specific and sensitivity of CT three-dimensional reconstruction were superior than those of the DR examination.CT three-dimensional reconstruction was much better than DR in the aspect of reexamination accuracy rate after surgery.Conclusion:Multislice CT three-dimensional reconstruction technique is accurate and reliable in the judgement of ankle fractures patients’ preoperative classification and reexamination after surgery.

2015 Vol. 12 (18): 32-33 [Abstract]( 431 HTML (1 KB)  PDF  (697 KB)  ( 207 )

WU Hong-zhi,YANG Meng,WANG Xia,et al.

Objective:To study the impact of autologous platelet-rich plasma gel treatment on wound microcirculation of electric burn patients.Method:90 cases of electrical burn patients in our hospital from February 2013 to October 2014 were selected as research subjects,they were randomly divided into two groups,45 cases in each group.The control group was given conventional fluid resuscitation therapy.The observation group was given autologous platelet-rich plasma gel treatment on the basis of conventional fluid resuscitation therapy.Wound microcirculation perfusion and wound capillary refill time before and after treatment were compared between the two groups,wound healing time and scar index were also compared between the two groups.Result:After treatment,the wound microcirculation perfusion of the observation group was higher than that of the control group,the wound capillary filling time of the observation group was shorter than that of the control group,the wound healing time and scar index of the observation group were less than those of the control group.The differences were statistically significant(P<0.01).Conclusion: Autologous platelet-rich plasma gel plays a significant role in improving the microcirculation of electric burn wound,it can also reduce wound scar and promote wound healing.

2015 Vol. 12 (18): 34-36 [Abstract]( 362 HTML (1 KB)  PDF  (720 KB)  ( 241 )

YANG Wei-hong,ZHONG Shou-jun,DUAN Li-feng,et al.

Objective:To observe and analysis the P16,ER and CEA protein expression in the cervical adenocarcinoma and endometrial adenocarcinoma and their clinical significance.Method:Immunohistoehemical method was used to detect P16,ER and CEA in paraffin-embedded tissues from 32 cases of endocervicaI adenocarcinomas and 32 cases of endometrial adenocarcinomas.The expression of P16,ER and CEA were retrospectively analyzed.Result:The positive rates of P16,ER,CEA in the cervical adenocarcinoma were 65.63%(21/32),28.13%(9/32),81.25%(26/32),respectively;those in
endocervicaI adenocarcinoma were various 9.36%(3/32),75.00%(24/32),43.75%(14/32).P16 and CEA in the cervical adenocarcinoma positive expression rate were higher than those of endometrial adenocarcinoma(P<0.05).Endometrial adenocarcinoma in the positive rate of ER was obviously higher than that of the cervical adenocarcinoma(P<0.05).Conclusion:Joint detection expression of P16,ER and CEA protein has great clinical application value in the differential diagnosis of endocervical and endometrial adenocarcinomas.

2015 Vol. 12 (18): 36-38 [Abstract]( 525 HTML (1 KB)  PDF  (719 KB)  ( 330 )

LI Fang-zhi,HUANG Guang-xiong,LU Feng-yue.

Objective:To investigate the proportion of Adenosine deaminase 2(ADA2) in total ADA activity of the tuberculosis pleural effusion and its cellular source in pleural tissue.Method:The total ADA and ADA2 activity from thirty-two tuberculosis patients’ effusions were measured.The cellular source of ADA2 were examined by immunohistochemistry method using CECR1 antibody.Result:The ADA2 contributed 74.8% to the total ADA.The immunohistochemistry of ADA2 in the pleural tissues of tuberculous pleural effusion showed that langhans cells,epithelioid cells and macrophages were stained deeply.Their cytoplasm and membrane were deposited by yellow granules.Conclusion:ADA2 is primarily responsible for total ADA activity in tuberculosis pleural effusion and it is secreted by macrophages,epithelioid cells and langhans cells.

2015 Vol. 12 (18): 39-40 [Abstract]( 422 HTML (1 KB)  PDF  (747 KB)  ( 329 )

WANG Dong-jiang,XU Ping.

Objective:To investigate the clinical efficacy of Enalapril combined with Betaloc in the treatment of hypertension.Method:98 cases of hypertension patients in our hospital were selected as the study objects,they were randomly divided into the observation group and the control group,49 cases in each group.Patients in the control group were given extended release nifedipine tablets treatment,the observation group was treated with Enalapril and Betaloc.The clinical efficacy of the two groups were analyzed.Result:The total effective rate of the observation group was significantly higher than that of the control group (P<0.05).The adverse reactions rate of the observation group was significantly lower than that of the control group(P<0.05).The blood pressure of the two groups had no significant difference before treatment(P>0.05).After the treatment,the situation of the two groups were both improved,but the improvement of the observation group was much better than that of the control group (P<0.05).Conclusion:Using Enalapril combined with Betaloc in the treatment of hypertension can be effectively and improve patients’ blood pressure.It has high security and should be popularized and applied.

2015 Vol. 12 (18): 41-43 [Abstract]( 562 HTML (1 KB)  PDF  (720 KB)  ( 193 )

YAO Rong-wei,OUYANG Shao-ji,XU Xue-jiang.

Objective:To investigate the clinical effects of tympanostomy tube insertion combined with adenoidectomy for children with secretory otitis media.Method:110 cases of children with secretory otitis media in our hospital from January 2011 to January 2014 were randomly divided into the research group and the control group,55 cases in each group.The research group was treated with tympanostomy tube insertion combined with adenoidectomy.The control group was treated with tympanostomy tube insertion.The changes in hearing,middle ear effusion time,total effective rate,complications and recurrence rate were compared between the two groups.Result:The hearing ability of the two groups improved,the improvement degree of the research group was better than that of the control group(P<0.01).Middle ear effusion time,total effective rate,complications and recurrence rate of the research group were significantly better than those of the control group(P<0.05).Conclusion:Tympanostomy tube insertion combined with adenoidectomy for children with secretory otitis media has exact effect.It can effectively improve the hearing and reduce related complications.It’s worthy of clinical application.

2015 Vol. 12 (18): 43-45 [Abstract]( 498 HTML (1 KB)  PDF  (720 KB)  ( 232 )

ZHANG Xianhua,FAN Huai-zhou,LI Zi-feng.

Objective:To investigate the clinical characteristics and influence factors of young acute myocardial infarction (AMI) in Shantou City.Method:AMI diagnosed by coronary angiography were selected in our hospital from January 2012 to December 2014 during the new entrants to Shantou area hospital,128 patients with AMI of age ≤ 45 years old were selected as observation group and 316 elderly patients with AMI of age ≥ 65 years old were selected as control group,clinical characteristics and influential factors of young AMI were analyzed.Result:The AMI incidence of observation group was 25.10%,which was significantly lower than 61.96% of control group,the difference was statistically significant( 字2=8.19,P<0.05);AMI first symptoms and typical chest pain of observation group were much more,heart failure,arrhythmia and carcinogenic shock were significantly less,the differences were statistically significant(P<0.05);the average involving coronary of observation group was(1.13±0.21),which was significantly lower than ( 2.18±0.46) of control group,and left main coronary lesions involving was significantly less than control group,the differences were statistically significant(P<0.05);the incidence rate of male,smoking,drinking,positive family history,emotional and dramatic movement for youth AMI were significantly higher than elderly AMI,while the incidence rate with hypertension and diabetes were significantly lower than elderly AMI,the differences were statistically significant(P<0.05).Conclusion:Young AMI chest pain typical symptoms,involving coronary is less,and for positive family history men,getting rid of bad habits helps to reduce the occurrence of disease risk.

2015 Vol. 12 (18): 46-48 [Abstract]( 559 HTML (1 KB)  PDF  (707 KB)  ( 185 )

DENG Haibo,HUANG Zhen.

Objective:To observe the curative effect of combine traditional Chinese and Western medicine treatment on patients after PKRP.Method:60 suitable patients with kidney deficiency and blood stasis who were after PKRP operations from January 2014 to December 2014 were randomly divided into the treatment group(n=30)and the control group(n=30).All patients were given corresponding treatment in perioperation period.Parameters included international prostate symptom score (IPSS),quality of life score(QOL),maximum urinary flow rates(Qmax),and hematuria were observed before the operation and 1 week,2 weeks after the surgery.Result:Compared with the preoperative,IPSS,QOL,Qmax of two groups were significantly improved,the differences were statistically significant(P<0.05).But 2 weeks after the surgery,IPSS,QOL between the two groups had significant difference(P<0.05);however,hematuria,after operation there was no significant difference in both groups.Conclusion:In the perioperative auxiliary treatment using traditional Chinese medicine can not only significantly improve lowerurinary tract symptom( LUTS)after surgery,but also do not increase the risk of postoperative delayed hemorrhages.

2015 Vol. 12 (18): 49-52 [Abstract]( 680 HTML (1 KB)  PDF  (730 KB)  ( 310 )

TAN Shu-ying,WANG Yun-lin,LIANG Chun-yan,et al.

Objective:To discuss the relationship between the characteristics of lipid body distribution and carotid artery intima-media thickness in patients with type 2 diabetic.Method:76 patients with type 2 diabetes mellitus(type 2 diabetes group) and 34 healthy subjects( control group) were enrolled in this study.WC,HC,W,BF,TrF,UF,LF,IMT,serum leptin levels were detected,and WHR,BF%,TrF/BF were calculated.Differences of the above indexes between the two groups were compared,and the relationship between the characteristics of lipid body distribution and carotid artery intima-media
thickness on patients with type 2 diabetic were analyzed.Result:WC,WHR,BMI,BF,TrF,UF,LF,BF%,TrF/BF,IMT,serum leptin levels of patients with type 2 diabetes were significantly higher than those of control group(P<0.05).Pearson correlation analysis showed that BF,TrF,UF,LF,BF%,TrF/BF were positively correlated with IMT,serum leptin levels (P<0.05),serum leptin level was positively correlated with IMT(P<0.05).Multiple regression analysis showed that TrF/BF and leptin were the independent risk factors of IMT.Conclusion:The distribution of body fat in patients with type 2 diabetes mellitus are abnormal,IMT and leptin increase significantly,and IMT and leptin are closely related with fat distribution characteristics.

2015 Vol. 12 (18): 52-54 [Abstract]( 505 HTML (1 KB)  PDF  (720 KB)  ( 221 )

PENG Feng-mei,LI Dong-lan,CHEN Hui.

Objective:To discuss the effect of Aspirin joint low molecular weight heparin in the treatment of habitual abortion.Method: From May 2013 to April 2014,84 cases of obstetrics and gynecology clinic of habitual abortion in our hospital were selected and divided into three groups,group A, group B,group C in accordance with random digit table,each group had 28 cases.Three groups of patients were given different treatment,after treatment,the treatment effect of the three groups were compared.Result:The pregnancy,postpartum bleeding,abortion pregnant weeks,preeclampsia,gastrointestinal reaction and the incidence of thrombocytopenia of the three groups,the comparison results displaied no significant difference(P>0.05).There were statistically significant differences in the absolate live-birth rate,live-birth rate,delivery pregnancy week,the incidence rates of abortion and ecchymosis among the three groups(P<0.05).Conclusion:Habitual abortion choice of Aspirin joint low molecular weight heparin was significant improvement the outcome of pregnancy,significant clinical value,can be applied.

2015 Vol. 12 (18): 55-57 [Abstract]( 622 HTML (1 KB)  PDF  (708 KB)  ( 197 )

YUAN Zhao-hong,YOU Yu-hui,JIANG Xiu-fang,et al.

目的:探讨小儿肺咳合剂对咳嗽变异性哮喘患儿肺功能、血清IgE 及外周血EOS 的影响。方法:回顾性选取本院2010 年10 月-2013 年10 月收治的100 例儿童咳嗽变异性哮喘患者作为研究对象,将其随机分为观察组和对照组,每组各50 例。对照组均给予常规治疗,观察组在对照组基础上,同时给予小儿肺咳合剂,1 剂/d,两组患者均以4 周为一疗程。观察并比较两组患者治疗后的咳嗽频率和咳嗽强度症状、记录他们的体征积分,比较治疗前后两组患者的肺功能和血清IgE 及外周血EOS。结果:治疗后,观察组治疗总有效率高于对照组,患儿症状积分及肺功能改善情况均显著优于对照组,两组比较差异均有统计学意义(P<0.05);治疗后两组患者血清IgE 及外周血EOS 都得到显著降低,且观察组的测量值明显低于对照组,两组患者的疗效比较差异有统计学意义(P<0.05)。结论:小儿肺咳合剂能抗变应性炎症,降低气道的高反应性,治疗儿童咳嗽变异性哮喘疗效显著。

2015 Vol. 12 (18): 58-61 [Abstract]( 501 HTML (1 KB)  PDF  (729 KB)  ( 223 )

LIN Ming,CHE Qun-jiang,LIANG Hai-bo.

Objective:To approach curative effect detection of percutaneous compression plate and hollow compression screw in treatment of middle-aged and young shift type femoral neck fracture.Method:Clinical data of 50 cases of middle-aged and young shift type femoral neck fracture patients in our hospital bone surgery from January 2013 to October 2014 were analyzed,they were divided into two groups,percutaneous compression plate group 25 cases and hollow compression screw group 25 cases.Result:The operation time,intraoperative blood loss,postoperative function recovery time of hollow compression screw group middle-aged and young shift type femoral neck fracture patients were lower than percutaneous compression plate group,the rate of good postoperative function of hollow compression screw group middle-aged and young shift type femoral neck fracture patients were better than percutaneous compression plate group,femoral head necrosis,coxa vara,return nail of hollow compression screw group middle-aged and young shift type femoral neck fracture patients were lower than percutaneous compression plate group,the differences were statistical significance(P<0.05).Conclusion:The injury is little of treatment middle-aged and young shift type femoral neck fracture by hollow compression screw,the effect is obviously,which is to be used.

2015 Vol. 12 (18): 61-64 [Abstract]( 554 HTML (1 KB)  PDF  (742 KB)  ( 306 )

LIN Bin,TAO Yang,WANG Dong-ning.

Objective:To analyze the value of CT,MRI and MRA in the diagnosis of posterior circulation ischemia vertigo.Method:35 patients with posterior circulation ischemic vertigo were given CT,MRI and MRA examination.The results of the examination were compared.Result:The results of CT and MRI examination had statistical difference(P<0.05),MRA showed the types of arterial insufficiency.Conclusion:Magnetic resonance has important value in assessment of post circulation ischemia vertigo.

2015 Vol. 12 (18): 64-65 [Abstract]( 506 HTML (1 KB)  PDF  (698 KB)  ( 197 )

XU Jin-fang,RU Wen-yuan,YU Wen-you.

Objective:To investigate the clinical value of serum and urinary cystatin C( CYS) in the different period of hemorrhagic fever with renal syndrome( HERS) in patients with acute kidney injury( AKI).Method:From March 2010 to October 2012 in our hospital,36 cases of renal syndrome hemorrhagic fever were selected as observation group in this study,36 cases of specimens were also selected as the basis to clinical stage and were divided into the heating period/hypotension shock stage,oliguria stage,transition stage and polyuria period/recovery period;at the same time were selected for health examination in our hospital in 35 normal subjects as control group in this study.Serum creatinine in two groups of subjects was determined by enzymatic method,using enzyme-linked immunosorbent assay for two groups of subjects,blood urine cystatin C were determined,and the structure determination of two groups of patients were analyzed.Result:In period of fever period/ hypotension,shock stage,less urine period,transition period and diuresis/recovery phase,serum cystatin C,urine cystatin C and serum creatinine level had significant difference between the observation group and the control group(P<0.05),and there were statistically significant differences in the serum,serum creatinine and urinary cystatin C between the purification group and no purification group(P<0.05).Conclusion:Markers in serum and urine cystatin C as hemorrhagic fever with renal syndrome of
acute kidney injury,can effectively respond to the severity of acute kidney injury in patients,renal syndrome of urinary cystatin C and renal tubular injury more consistent hemorrhagic fever of acute kidney injury,clinical value is significant,can be widely used in large range in the clinical.

2015 Vol. 12 (18): 66-68 [Abstract]( 574 HTML (1 KB)  PDF  (706 KB)  ( 207 )

ZHANG Gao-feng,LIU Heng.

Objective:To evaluate the effect of PACS network combined with panel discussion method in medical imaging experimental teaching in“ Three of the students”.Method:The students of grade 2010 from Zunyi Medical College School of medicine and Scien were selected as the research object.In the medical imaging experimental teaching,they were divided into experimental group and control group.The experiment group adopted the group discussion teaching method,the control group adopted traditional teaching methods.After teaching,the teaching was evaluated by questionnaire test and students’ way.Result:Average score of experimental group was( 82.3±8.6),average score of control group was( 72.6±7.3),92.3% of students thought that the new teaching mode was very interesting.Conclusion:PACS system combined with group discussion method is suitable for the three students medical imaging experimental teaching.

2015 Vol. 12 (18): 69-71 [Abstract]( 563 HTML (1 KB)  PDF  (718 KB)  ( 203 )

PAN Xiao-yun.

Objective:To explore the application of PBL in clinical teaching in surgery.Method:Teaching cases were designed based on teaching objectives and contents,the related issues were widely discussed in groups.After consulting the documents and materials,all issues were primarily summarized and reported by students and then completed and responded by teachers.Finally the effectiveness of PBL was investigated and evaluated through questionnaires.Result:93% of all students believed PBL could raise their learning ability and 86.7% of the students thought this teaching mode could improve their collaborative capability and studying interest.Conclusion:The application of PBL in surgery clinical teaching could stimulate students,studying ability,learning interest,collaborative capability,analytical ability and thinking skills,which gives a direction for the reformation of surgical education.

2015 Vol. 12 (18): 72-73 [Abstract]( 593 HTML (1 KB)  PDF  (675 KB)  ( 236 )

WU Linxiu,LIU Chun-bin.

Every year about 300,000 people in China was diagnosed as Alzheimers’s s disease( AD),AD is a continuous pathological physiology process,including pre-MCI(mild cognitive impairment,MCI),MCI and dementia.Research shows MCI can progress to AD at a rate of 10%-15% every year.According to the experience from nursing intervention for diabetic patients with mild cognitive impairment in clinic,we wrote this paper which might play an important role to improve the quality of life for diabetic patients with mild cognitive impairment and slowing down or even reverse the procession of AD.

2015 Vol. 12 (18): 74-76 [Abstract]( 535 HTML (1 KB)  PDF  (708 KB)  ( 255 )

YI Xian-lin.

Gynecological apparatuses centralized management of cleaning,disinfection,packaging and sterilization can not only promote the rational distribution of hospital resources but effectively reduce the workload of clinical departments to ease their burden.It also can provide specialized disinfection services for clinical departments so as to decrease the cross-infection in hospital,ensure the safety of health care and improve the satisfaction of clinical departments to disinfection supplies.

2015 Vol. 12 (18): 77-79 [Abstract]( 413 HTML (1 KB)  PDF  (706 KB)  ( 170 )

YE Ruixiang,WU Jian-wei,LUO Ling-min.

Objective:To study the value of nursing intervention before capsule endoscopy bowel preparation time. Method:60 patients who underwent capsule endoscopy in our hospital were selected from July 2013 to November 2014 and were randomly divided into control group and observation group,30 cases in each group.The patients of control group were given conventional reservation method,the observation group was given nursing intervention on the basis of control group,the effect of bowel preparation and the impact on test results were observed.Result:The patients of observation group with intestinal cleanliness,inspection results and a success rate were better than the control group,capsule endoscopy in the stomach of patients in the observation group the lag time was shorter than the control group,the lag time was longer than its intestinal control group,the observation group of SAS scores,SDS score,quality of health care knowledge and satisfaction scores were significantly better than the control group,all the differences were statistically significant(P<0.05).Conclusion:Comprehensive and individualized nursing intervention before capsule endoscopy can improve intestinal cleanliness,improve the patients of inspection results,the mental state,knowledge and satisfaction.

2015 Vol. 12 (18): 79-81 [Abstract]( 541 HTML (1 KB)  PDF  (706 KB)  ( 276 )

ZHU Yan-jun.

Objective:To analyze the method and effect of training for caregivers of the chronically ill to enhance their ability of nursing.Method:100 caregivers of the chronical illness were trained with application of the training module designed by our hospital to improve their nursing ability.After training,their nursing ability were compared with before the training.At the same time,the satisfaction of the chronically ill for the caregivers before and after the training and attitude of the caregivers towards the training were researched.Result:After the training,the caregivers knew much more about the nursing knowledge and
nursing technique,the differences were statistically significant(P<0.05).Meanwhile,the satisfaction of the chronically ill to the caregivers remarkably improved,the differences were statistically significant(P<0.05).Conclusion:Improving the ability of nursing training for caregivers of the chronical illness can not only improve their nursing ability but also improve the patients’ satisfaction for them,it can help the recovery of patients quickly.

2015 Vol. 12 (18): 82-85 [Abstract]( 612 HTML (1 KB)  PDF  (740 KB)  ( 195 )

ZHANG Kui.

Objective:To study the effect of comprehensive nursing intervention in peptic ulcer with bleeding. Method:92 cases of peptic ulcer with bleeding of our hospital from May 2012 to May 2014 were selected and divided into control group and experimental group.The experimental group was given comprehensive nursing intervention and the control group was given conventional nursing.Then bleeding and clinical efficacy after giving nursing between the two groups were compared.Result:After nursing,total effective rate of symptoms improved of gastrointestinal bleeding in the experimental group was 93.48%,that of the control group was 71.74%,the total effective rate of symptoms improved of gastrointestinal bleeding in the experimental group was significantly better than that of the e control group( P<0.05).And total effective rate of treatment of the experimental group was 91.30%,that of the control group was 73.91%,the total effective rate of treatment of the experimental group was significantly higher than that of control group,the difference was statistically significant( P<0.05). Conclusion:Comprehensive nursing intervention can significantly reduce the bleeding symptoms of patients with peptic ulcer with bleeding,promote healing of the ulcer surface,relieves the patient’s clinical signs.It can be used as one of the important auxiliary measures of treatment of peptic ulcer with bleeding.

2015 Vol. 12 (18): 85-88 [Abstract]( 439 HTML (1 KB)  PDF  (741 KB)  ( 168 )

DENG Gui-zhen,TAN Rui-zhen.

Objective:To study the treatment effect of improved posture,located at the side of the subclavian and axillary vein catheter in premature infant PICC catheter.Method:Premature infants with PICC catheter from June 2013 to December 2014 were selected,whose tips were on the side of the subclavian and axillary vein. Different methods were used to improved posture of ectopic catheter adjustment, monitoring after adjustment effect.Result:The contralateral subclavian vein experimental A group once correct success rate was higher than the control A group,with statistically significant differences(P<0.05),the axillary vein once correct success rate in the experimental B group was higher than the control B group,no statistical significance (P>0.05).Catheteriztion time in the contralateral subclavian and axillary vein catheter of the experimental group had obvious differences statistically significant(P<0.05).Two groups in the incidence of phlehitis had no statistical significance difference (P>0.05).Conclusion:Adopting improved position in PICC catheter is carried out in the side of the subclavian and axillary vein,it is a simple operation,conveniently reduce the transfusion exosmosis,the suffering painess of patients and the burdens of families.

2015 Vol. 12 (18): 88-90 [Abstract]( 557 HTML (1 KB)  PDF  (720 KB)  ( 320 )

HUANG Ai-jing,WU Fu-cheng.

Objective:To study the effect of comprehensive nursing intervention on 6 minutes walk test for patients with chronic heart failure.Method:70 patients with heart function NYHA class Ⅱ-Ⅳ and stable condition of chronic heart failure were randomly divided into two groups,with each group 35 cases.The control group was given conventional nursing,while the observation group was given comprehensive nursing intervention,patient’s heart function and psychological condition were assessed,preparing for health education and first aid were included in the process.The complete status of the test,the
coincidence rate of the test results and the NYHA heart function classification were compared between the two groups.Result:The coincidence rate of the test results and the NYHA heart function classification of the control group were significantly better than those of the control group,the difference was statistically significant(P<0.05).Conclusion:Comprehensive nursing intervention on 6 minutes walk test can effectively evaluate the cardiac function of patients with chronic heart failure,it is worth popularizing in clinical application.

2015 Vol. 12 (18): 91-92 [Abstract]( 535 HTML (1 KB)  PDF  (698 KB)  ( 224 )

YE Chun-yan.

Objective:To study the effects of continuing nursing for QQL of stable COPD patients.Method:80 stable COPD patients in our hospital were selected from February 2013 to February 2014 and randomly divided into observation group and control group,40 cases in each group.The control group was treated with education management,symptomatic treatment and other conventional cares;on the basis of that the observation group was also treated with continuing nursing included home oxygen therapy and respiratory gym,QQL of two groups were compared.Result:Before nursing,CAT of two groups were generally
consistent;after 3 monthes and 6 monthes of nursing,CAT of observation rvation group were( 16.1±5.2) scores and( 16.6±4.4)scores while CAT of control group were( 21.4±6.5) scores and( 21.8±6.2) scores,the differences were statistically significant (P<0.05).Before nursing,lung function indexes were generally consistent;after 6 monthes of nursing,lung function indexes of observation group were significantly better than those of control group,the differences were statistically significant(P<0.05).Conclusion:For stable COPD patients,the continuing nursing of home oxygen therapy combined with respiratory gym can effectively improve the patients’ QQL and symptoms.

2015 Vol. 12 (18): 93-95 [Abstract]( 440 HTML (1 KB)  PDF  (720 KB)  ( 207 )

ZHANG Qiu,LI Da-ping.

As the birthplace of traditional Chinese medicine,development and application about integrated medicine is much lower than expected.Debates on integrated medicine have been present,the modern medical model encourages that man is not just an organism,the patients’ interests and autonomy should be concerned about most.This article attempts to complement and perfect the concept,existing questions and future direction from the point of view on“ patient-centered”.

2015 Vol. 12 (18): 96-99 [Abstract]( 575 HTML (1 KB)  PDF  (739 KB)  ( 218 )

LI Dong,YI Dongsheng,ZHONG Yuan-mei.

Objective:To analyze occupation distribution and personality typing of solid breast lesions and provide evidences for the reason of disease of study,prevention and intervention.Method:200 patients with breast cancer from January 2011 to October 2014 in Futian district were randomly selected as the observation group,at the same time,200 normal healthy women were selected as control group.The basic condition and occupation of patients by questionnaire were collected,occupation of respondents was classified and control analyzed.Minnesota Multiphasic Personality Questionnaire was applied,personality typing of patients of two groups were compared.Result:The tendency of electronic,chemical workers:workers,plastic processing workers,teachers and the self-employed had breast solid mass disease(OR values were greater than 1,P<0.05).Arts and crafts design personnel,accounting,nurses,the government public workers and unemployed had protective effect on breast solid tumor diseases(OR values were less than 1,P<0.05).Personality not stable type of the observe group was 59.0%(118/200),stable type was 41.0%(82/200);personality not stable type of the control group was 45.5%(91/200),stable type was 54.5%(109/200).The two group had significantly difference in statistics( 字2=7.305,P<0.05).Patients of the observation group with hypochondriasis,depression,hysteria,psychopathic bias,mental decline,hypomania and social
introversion scores were significantly higher than those of control group(P<0.05).Conclusion:In the electronic,chemical,plastics processing teacher’s occupation and the self-employed occupation and they have depression,hysteria,psychopathic bias,psychasthenia,hypomania and other personality traits to induce breast solid mass,suggest taking protective and mental occupation support actively,reducing the effect.

2015 Vol. 12 (18): 99-101 [Abstract]( 470 HTML (1 KB)  PDF  (720 KB)  ( 235 )

CHEN Qing-zhao,LIAO Wei-feng,LIN Sheng-na.

Objective:To analyze the differences of curative effects between electronic health record and paper health record used in hypertension management.Method:1000 samples were randomly selected and divided into electronic health record group and paper health record group,with each group 500 cases.The methods of questionnaire and blood pressure monitoring were used in the research.One year after the intervention,the differences of curative effects between the two groups were evaluated.Result:Patients in the two groups were both improved in the aspects of lifestyle,self-management ability and blood pressure control rate.There were statistically significant differences between the two groups in the aspects of treatment compliance,medication compliance and blood pressure control rate(P<0.05).Conclusion:Health management has positive effects on the hypertension prevention and control.The electronic health record does better than the paper health record in curative effect.

2015 Vol. 12 (18): 102-104 [Abstract]( 423 HTML (1 KB)  PDF  (707 KB)  ( 157 )

LAI Xin,LIU Xiao-ying,SANG Mei-li.

The authors search all the nursing patents from 1985 to 2013 in Shan Xi province by retrieving the patent database of CNKI and searching the websites of State Intellectual Property Office of the P.R.C,SooPAT and patentstar,the overall situation of application,the annual filings,regional distribution situation,legal status of patents,the patentee distribution and technology classification of patents are statistically analyzed.It will provide theoretical reference for production and application of achievements in nursing scientific research in Shan Xi province.

2015 Vol. 12 (18): 104-106 [Abstract]( 439 HTML (1 KB)  PDF  (763 KB)  ( 412 )

WANG Song-xin.

Objective:To use acupuncture treatment for facial paralysis disease, in order to improve the treatment of the disease.Method:From April 2013 to April 2014, 80 patients with peripheral facial paralysis were selected and randomly divided into two groups, acupuncture treatment group( 40 cases) and acupuncture control group( 40 cases).The patients accepted 0.3 mm × 50 mm cents acupuncture points for each patient, and then get gas to fill every interval of 10 minutes flat-reducing way line pin 1, and the needle 30 times, then on Shimonoseki, Yifeng two acupuncture points simultaneously, until the local variable flush so far.The acupuncture control group used purely acupuncture treatment, the method with acupuncture the same treatment
group, divided two groups of acupuncture treatments for a course of treatment 16 times a day acupuncture 1, after completing a course of a day of rest, sustained two courses of treatment.The two groups were compared by Prommnn HB evaluation system.Result:The cured rate and markedly effective rate of the acupuncture treatment group was 54.21%, 85.46%, respectively, while that of the acupuncture control group was 34.52%, 55.48%, there was statistically significant difference between the two groups (P<0.05).Also, the patient symptom scores compared between the two groups showed statistically significant difference( P<0.05).Symptom score and HB facial nerve function classification after treatment compared between the two groups showed statistically significant difference( P<0.05), but no before.Markedly effective time compared between the two groups showed statistically significant difference( P<0.05), too.Conclusion:According to the theory of Chinese medicine treatment, acupuncture treatment effect is significant, also effectively prevent the emergence and impact-related complications and side effects, especially for aspects of the patient’s symptoms, the cure rate, markedly effective rate has a significant role, while economic, convenient features also make it easy to broader clinical application.

2015 Vol. 12 (18): 107-109 [Abstract]( 608 HTML (1 KB)  PDF  (721 KB)  ( 179 )

XIE Zhe-hua,DENG Li-ling,TANG Zhi-qun.

Objective:To summarize the biological agent fixed tibial plateau fracture defect after observation and nursing.Method:35 patients in our hospital application of biological agent’s fixation of tibial plateau fracture defect patients were selected as research subjects and were retrospectively analyzed the postoperative care methods.Result:The group of patients with active biological agents fixation and postoperative rehabilitation care,postoperative hospital stay 14-28 d after discharge.Knee function excellent in 28 cases,good in 5 cases,and available in 2 cases,the excellent and good rate was 94.29%.Conclusion:In
biological agents fixed tibial plateau fracture defect after surgery for patients with early rehabilitation care and close observation of the patient’s condition changes,to improve postoperative knee function in patients with significant.

2015 Vol. 12 (18): 109-110 [Abstract]( 425 HTML (1 KB)  PDF  (688 KB)  ( 183 )

HE Ru-bi,HU Hai-bin,LIANG Yan-xia.

Objective:To discuss effect of pregnancy depression psychological counseling to promote the natural childbirth of pregnant women.Method: 96 cases of pregnant women from obstetrics and gynecology department of our hospital between February 2012 to October 2013 were selected and randomly divided into interventional group( n=132) and control group (n=124).All pregnant women were given conventional care,and the interventional group was added psychological nursing intervention.The delivery mode,natural delivery process,postpartum hemorrhage and neonatal asphyxia rate were compared.Result:The rate of natural childbirth of the two groups were 61.36% and 55.65%,with statistically significant difference between the groups(P<0.05);the natural delivery process and postpartum hemorrhage of the interventional group were lower than the control group(P<0.05);the incidence rate of neonatal asphyxia of the two groups were 1.52% and 2.42%,with statistically significant difference between the groups( P<0.05).Conclusion:The psychological nursing intervention can effectively improve the natural delivery rate,shorten the natural childbirth birth process, reduce postpartum bleeding and neonatal asphyxia,with a positive significance to the improvement of the quality of life of mother and infant.

2015 Vol. 12 (18): 111-113 [Abstract]( 453 HTML (1 KB)  PDF  (708 KB)  ( 184 )

XU Wei-zhong,FU Yan-dao,WU Hai-dan.

Objective:To analyze the reasonable application of Western medicine drugs as well as the management measures.Method:100 Western medicine pharmaceutical prescription were selected as the research objects in our hospital pharmacy department from January 2012 and February 2012.According to the problems arising from the prescription application give corresponding management measures,Western medicine and examination.From March 2013 to April 2014 100 Western medicine pharmacy prescription were extracted,after management and application,the actual situation was compared and analyzed.Result:Reasonable management applications before clinical medication at a rate of 70%,after a reasonable management applications in clinical rational drug use at a rate of 93%,after the examination of clinical rational drug use rate was better than just examination before and after statistical analysis,the difference between the two groups had statistical significance (P<0.05).Conclusion:The application of Western medicine drugs for reasonable management,can significantly improve the rate of clinical rational drug use.

2015 Vol. 12 (18): 113-114 [Abstract]( 445 HTML (1 KB)  PDF  (685 KB)  ( 218 )

LU Zi-zheng,GENG Yi-qun.

Objective:To evaluate the clinical effect of titanium mini-plate used in the complex maxillofacial fractures. Method:70 cases of maxillofacial fractures in our hospital were analyzed.Rigid internal fixation with corresponding titanium miniplate was given to the patients according to their different fracture shapes,the time of traction fixation for maxillofacial fractures was decided by the position of fracture.Result:After 3 months,observing the recovery condition of patients,69 cases were excellent,good in 1 case.Wound Class-A healing rate was 97.1%.3 cases occured postoperative complications of wound infection. The sequelae included 3 cases of short-term facial paralysis,4 cases of upper lip numbness,4 cases of preauricular pain and 6 cases of temporomandibular joint clicking.The situation of maxillofacial fracture healing was good after the treatment,with no titanium nails off and occurrence of rejection.Conclusion:The effect of titanium mini-plate used in the treatment of maxillofacial fracture is remarkable.

2015 Vol. 12 (18): 115-116 [Abstract]( 396 HTML (1 KB)  PDF  (675 KB)  ( 273 )

ZHOU Yu-xiong.

Objective:To investigate the application value of Cortisomol and Dentsply ah-plus paste in disposable root canal surgery in treating acute pulpitis.Method:234 acute pulpitis patients(258 diseased teeth)in dental clinic of our hospital were randomly divided into two groups,the observation group( 121 cases,130 diseased teeth) with root canal filling were given Primacaine paste,the control group( 113 cases,128 diseased teeth) with root canal filled were given ah-plus paste of Dentsply.The effects were compared between the two groups.Result:The adverse reaction rate of the observation group was significantly lower than that of the control group(P<0.05).241 teeth were reexamined after 1 year,the reexamine rate was 93.41%( 241/258),
in the observation group 9 cases lost follow-up and in the control group 8 cases.Therapy efficiency rate and satisfaction rate of the observation group were significantly higher than those of the control group( P<0.05).Conclusion:The application value of cortisomol in the disposable root canal surgery in treating acute pulpitis is more significant than Dentsply ah-plus paste,the former is worthy of clinical application.

2015 Vol. 12 (18): 117-119 [Abstract]( 532 HTML (1 KB)  PDF  (709 KB)  ( 246 )

ZHAO Chun-ning,WU Hong,ZHANG Xiao-yu.

Objective:To explore the ocular surface manifestations of systemic lupus erythematosus patients.Method:26 patients who were confirmed with systemic lupus erythematosus in our hospital from April 2014 to December 2014 were selected as the SLE group,20 patients from the ophthalmology clinic outpatient who had no systemic lupus erythematosus were selected as the control group.The ocular surface manifestations of the SLE patients was compared with that of the control group(20 cases)through cornea fluorescein staining,Schirmer test and test of tear film breaking up time.Result:Compared with the control group,the mean BUT of the SLE group was significantly shorter(t=2.62,P<0.05),the value of Schirmer Ⅰ test of the SLE group was significantly lower(t=2.62,P<0.05)and the positive rate of cornea fluorescein staining of the SLE group was significantly higher.Conclusion:Patients with systemic lupus erythematosus show a tendency to have changes of ocular surface state.They are susceptible population of dry eyes.Corneal fluorescein staining,Schimer Ⅰ test and tear film breaking up time test help to find abnormal changes of ocular surface state of SLE patients.

2015 Vol. 12 (18): 119-121 [Abstract]( 524 HTML (1 KB)  PDF  (719 KB)  ( 178 )

YOU Yu-qing,YANG Wei-xia.

Objective:To research the difference in nursing effect between the high-frequency electric scissors in the lateral episiotomy cutting and the special tools of conventional lateral shear.Method:226 lying-in women who came to our hospital for natural childbirth were selected from April 2014 to April 2015 and divided into group A and group B,113 cases in each group.The patients in group A were given episiotomy nursing with high-frequency electric scissors while that of group B were given episiotomy nursing with traditional scalpel.The surgical instruments were compared in their influence on nursing effect.Result:In group A,degree Ⅰ perineal trauma of 98 patients,degree Ⅱ perineal trauma of 15 patients;in group B,degree Ⅰ perineal trauma of 86 patients,degree Ⅱ perineal trauma of 27 patients,no patients got injure more than degree Ⅲ,the difference was statistically significant(P<0.05).In group A,102 patients were mild postoperative pain and 11 patients were moderate postoperative pain;in group B,80 patients were mild postoperative pain and 33 patients were moderate postoperative pain,the difference was statistically significant(P<0.05).Conclusion:High-frequency electric scissor is more suitable for lateral episiotomy cutting.

2015 Vol. 12 (18): 122-124 [Abstract]( 390 HTML (1 KB)  PDF  (719 KB)  ( 167 )

TANG Chang-sheng,WANG Fang.

Objective:To analyze the effect of surgical castration on lipid metabolism in patients with prostate cancer.Method:45 patients with advanced prostate cancer had undergone the bilateral orchiectomy.The serum levels of T,FT,TG,TC,HDL-C,LDL-C,APO-A1,APO-B were determined before and after castration.Result:T and FT after castration were significantly lower than that before castration,and showed a gradual decrease from 1 month to 1 year,the differences were statistically significant(P<0.05);after castration,TG increased significantly 3 months after castration,TC and HDL-C increased significantly after castration,LDL-C decreased significantly after castration,the differences were statistically significant(P<0.05).APO-A1 and APO-B were not changed,the difference was no statistically significant(P<0.05).Conclusion:After surgical castration,the androgen levels decrease,and the lipid metabolism becomes abnormal.

2015 Vol. 12 (18): 127-128 [Abstract]( 612 HTML (1 KB)  PDF  (685 KB)  ( 167 )

CHENG Xi-jian.

Objective:To explore the feasibility of auricular acupoint sticking combining Shuangbo pulvis hot compress treating patients with postoperative ovarian premature aging undergoing laparoscopic oophorocystectomy.Method:Forty-four patients with premature ovarian failure after laparoscopic oophorocystectomy admitted by the Hospital from February 2014 to May 2014 were selected as research subjects,who were divided into the he treatment group( 22 cases,subject to auricular acupoint sticking combining Shuangbo pulvis hot compress)and control group( 22 cases,subject to hormonotherapy).The efficacy of two groups were compared.Result:The comparisons differences in levels of FSH,E2 and LH hormone in two groups before treatment was not statistically significant difference(P>0.05).The levels FSH and LH hormone levels in the treatment group after treatment were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).The level of E2 hormone and total effective rate in the treatment group after treatment were significantly higher than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The auricular acupoint sticking and combining Shuangbo pulvis hot compress can strengthen the self-stability state of ovary,promote postoperative hematopoietic function and proliferation differentiation,and regulate ovarian function,and poses obvious effect on improving clinical symptoms of patients with premature ovarian failure,being worthy of clinical promotion.

2015 Vol. 12 (18): 129-131 [Abstract]( 485 HTML (1 KB)  PDF  (709 KB)  ( 220 )

ZHAN Xue-ping,JIANG Li-ya,LUO Jian-jiao,et al.

Objective:To explore the influence of the heat sensitive moxibustion on fracture healing.Method:60 patients with fracture after operation in our hospital were selected from October 2013 to September 2014 and were divided into control group and experimental group,30 cases in each group.The control group was given Chinese medicine treatment,the experimental group was given traditional Chinese medicine therapy combined with thermal moxibustion.Healing and pain disappearing time and pain score changes of fracture of the two groups were observed and compared.Result:In experimental group,fracture healing was significantly better than the control group,the difference was statistically significant( P<0.05);the experimental group pain disappearing time and the time of fracture healing were( 14.1±2.1)d and( 34.1±3.1)d,which were significantly shorter than( 24.3±3.8)d and( 49.5±2.7)d of control group,the differences were statistically significant( P<0.05);before the treatment,comparison of pain scores in two groups of patients had no significant difference(P>0.05);after treatment,the pain score of experimental group was( 0.32±0.11)scores,which was significantly lower than(1.41±0.23)scores of the control group of the control group,the difference was statistically significant(P<0.05).Conclusion:Based on the conventional medicine treatment combined with the heat sensitive moxibustion therapy can effectively promote the healing of fracture.

2015 Vol. 12 (18): 131-134 [Abstract]( 586 HTML (1 KB)  PDF  (742 KB)  ( 197 )

HUANG Qi-ren.

Objective:To explore the analysis of emergency medical causes of coma patients as well as the main treatment measures.Method:100 coma patients’ clinical data were retrospective analyzed,the main causes of unconsciousness and relative treatment measures were summarized.Result:The main causes of 100 patients in coma for cerebral hemorrhage,cerebral thrombosis,drug poisoning and acute organic phosphorus poisoning.12 h on the reason of the coma diagnosis accuracy rate was 80%,in 24 h the correct diagnosis of 97 cases.A total of 7 cases of patients died,of which 2 patients with large area cerebral hemorrhage caused by death,sudden cerebral thrombosis of 3 cases,acute organophosphate poisoning in 1 case,and 1 case of drug poisoning,the patients of death with GCS score were significantly lower than patients cured or improved,the difference was statistically significant(P<0.01).Conclusion:Early in a timely manner to internal causes coma patients diagnosis and symptomatic treatment is the key to improve the prognosis of patients.

2015 Vol. 12 (18): 134-135 [Abstract]( 538 HTML (1 KB)  PDF  (698 KB)  ( 194 )

ZHAO Zhen.

Objective:To approach curative effect detection of treatment hyperlipidemia by Atorvastatin calcium tablets. Method:50 patients with hyperlipidemia were selected in our hospital from April 2014 to Octomber 2014,which was to be divided into control group and detection group,25 cases in each group.The control group was treated by peroral Bezafibrate tablets,detection group was treated by peroral Atorvastatin calcium tablets.Result:Before treatment,compared the blood lipid indicators of two groups,the difference was no statistically significant(P>0.05).After 4 weeks of treatment,compared with the same group before treatment,the difference was statistically significant(P<0.01).Compared between the two groups,the difference was no statistically significant(P>0.05).After 8 weeks of treatment,compared between the two groups,the difference was statistically significant(P<0.05),and the detection group was better than that of the control group treatment effect.The carotid intima-media thickness and plaque area of two group before treatment were no obviously statistical differences (P>0.05).After treatment 4 weeks,the between the two groups compared with before treatment,carotid intima-media thickness and plaque area of patients were obviously statistical differences(P<0.01),compared two groups,the difference was no statistically significant(P>0.05).After treatment 8 weeks,compared the two groups had statistical difference(P<0.05),the curative effect of detection group was better than control group,the incidence of adverse reactions of detection group was lower than control group,the difference was statistically significant(P<0.05).Conclusion:The achieve satisfactory results of treatment hyperlipidemia by Atorvastatin calcium tablets are acquired,safe and reliable,it is should be widely used.

2015 Vol. 12 (18): 136-138 [Abstract]( 589 HTML (1 KB)  PDF  (708 KB)  ( 166 )

TIAN Jia-fu.

Objective:To discuss and analyze clinical situations of elderly patients with acute cholecystitis,to provide clinical reference standard treatment.Method:52 elderly patients with acute cholecystitis clinical data were retrospectirely analyzed in our hospital from January 2005 to December 2014.Result:The whole group of 52 patients,non-surgical treatment of 6 patients were discharged.The remaining 46 cases underwent surgical treatment,34 cases of cholecystectomy,gallbladder mucosal resection omissions three cases,gallbladder fistula in 9 cases.Postoperative wound infection in one case,a routine cholecystectomy three days,due to diabetes,coronary heart disease,died of multiple organ failure,and the remaining patients were cured.Conclusion:May take reasonable clinical treatments for patients based on the actual situation,in order to facilitate their recovery.

2015 Vol. 12 (18): 138-140 [Abstract]( 469 HTML (1 KB)  PDF  (706 KB)  ( 189 )

XIE Chu-xing.

Objective:To analyze clinical characteristics of children lobar pneumonia combined with mycoplasma pneumoniae infection,and offer the basis for the diagnosis of illness.Method:120 cases of mycoplasma pneumoniae infection hospitalized from August 2012 to August 2014 who were selected as study objects,there were 55 cases of bronchial pneumonia,who were selected as control group,there were 65 cases of lobar pneumonia combined with mycoplasma pneumoniae infection,who were selected as the observation group,age,pneumonia show,complications,treatment and prognosis of performance of children patients of two groups were compared.Result:Illness age incidence of children patients of the observation group were from five to twelve,fever(above 38.5 ℃),gastrointestinal symptoms,psychiatric symptoms,liver and cardiac damage,pleural effusion and pulmonary atelectasis complications were respectively 84.62%,24.62%,20.00%,52.31%,27.69%,those of the control group were 54.55%,9.09%,3.64%,23.64%,7.27%,the differences had statistical significance(P<0.05).X-ray absorption rates of two weeks of the observation group were significantly less than those of the control group(P<0.05),average hospitalization time of other two groups were[(18.20±3.58)d vs(12.08±1.85)d],the difference had statistical significances (P<0.05).Conclusion:Lobar pneumonia with pneumonia mycoplasma infection is main school aged children,easily combined
with pulmonary complications,course of treatment is long and chest X-ray absorption is relatively slow.

2015 Vol. 12 (18): 140-142 [Abstract]( 512 HTML (1 KB)  PDF  (708 KB)  ( 145 )

YANG Xiao-fang.

Objective:To compare the clinical effect between improved vaginal hysterectomy and abdominal hysterectomy for uterine benign lesions.Method:40 patients with non-prolapsed uterus lesions were randomly divided into the observation group and control group,20 cases in each group.The patients in the observation group were cured by improved vaginal hysterectomy while those in the control group were cured by abdominal hysterectomy.The time of operation,amount of bleeding in operation,passage of gas by anus,pain after operation,length of stay and complication after operation of the two groups were respectively compared.Result:The average time of operation,amount of bleeding in operation,incidence of surgical complications,passage of gas by anus,active time and average length of stay of the patients in the observation group were better than that of the control group,the differences were statistically significant(P<0.05).Conclusion:Improved vaginal hysterectomy has an advantage over abdominal hysterectomy with shorter time of operation,less bleeding,lower incidence of surgical complications,physical recovery faster,less expense and no scars of the surface.It is safe with excellent operation result so that it is worth popularizing in clinical application.

2015 Vol. 12 (18): 143-146 [Abstract]( 544 HTML (1 KB)  PDF  (741 KB)  ( 159 )

LI Zhi,YAN Zhi-jian.

Objective:To observe the clinical effect of PCS pedicle screw in treatment of spinal trauma-related disorders. Method:70 patients with spinal trauma-related disorders treated in our hospital from March 2012 to March 2014 were selected as the research objects.They were randomly divided into two groups,the control group was given normal system treatment of spinal pedicle screw,the observation group was given the treatment of PCS pedicle screw.The situation of operation,postoperative spinal nerve injury,Cobb’s angle before and after operation and VAS scores were compared between the two groups.Result:The observation group’s amount of bleeding,hospitalization,Cobb’s angle of six months after surgery and VAS score were significantly better than those of the control group(P<0.05).The spinal nerve injury of the two groups after surgery had no significant difference(P>0.05).Conclusion:PCS pedicle screw used in treatment of spinal trauma-related disorders is safe and reliable,patients can get a rapid postoperative recovery.It is worthy of promotion.

2015 Vol. 12 (18): 146-148 [Abstract]( 457 HTML (1 KB)  PDF  (721 KB)  ( 190 )

ZHOU Wei-zhong,LIANG Yuan,QIN Hua-qiang,et al.

Objective:To compare the efficacy of laparoscopic cholecystectomy( LC) combined with common bile duct exploration surgery( LCBD) and traditional open stone surgery for biliary calculi combined with infection in elderly patients and analysis the advantage of LC combined with LCBD.Method:120 biliary calculi combined with infection patients’ clinical date were retrospectively analyzed.They were divided into the laparoscopic group and the laparotomy group.The laparoscopic group was treated with LC combined with LCBD surgery,the laparotomy group was treated with traditional open stone surgery.Result:The  operation time of the laparoscopic group was significantly longer than that of the laparotomy group(P<0.001).The intraoperative blood loss,number of postoperative analgesic use,postoperative ambulation time, postoperative gastrointestinal function recovery time,postoperative stay days in ICU and postoperative hospital stays of the laparoscopic group were significantly lower than those of the laparotomy group(P<0.05).The postoperative bleeding rate,postoperative bile leakage rate and the incidence rate of postoperative residual stones in the two groups had no significant difference(P>0.05).The postoperative infection rate of the laparoscopic group was significantly lower than that of the laparotomy group(P<0.05).Conclusion:In the treatment of Biliary calculi combined with infection in elderly patients,compared with the traditional open stone surgery,LC combined with LCBD has the advantages of less blood loss,faster recovery,shorter hospital stays and lower postoperative infection rates.

2015 Vol. 12 (18): 149-152 [Abstract]( 648 HTML (1 KB)  PDF  (743 KB)  ( 243 )

HU Wei,WANG Li-li.

Objective:To clarify the effects of Telmisartan combined with Spironolactone on early recurrence after catheter ablation for paroxysmal atrial fibrillation in patients.Method:96 patients with PAF treated by catheter ablation were randomly divided into control group and observational group,48 cases in each group,the control group was treated with Warfarin and Amiodarone,the observational group was treated with Telmisartan and Spironolactone.Result:The rate of PAF early recurrence in observational group was 6.25%,which was significantly lower than 22.92% of the control group,the difference was statistically significant( P<0.05).After surgery 1 month,HsCRP in observational group was higher than the control group;after surgery 3 month,NT-proBNP in observational group was lower than the control group,the differences were statistically significant (P<0.05).Conclusion:Telmisartan combined with Spironolactone reduce early recurrence after catheter ablation of PAF.

2015 Vol. 12 (18): 152-153 [Abstract]( 573 HTML (1 KB)  PDF  (686 KB)  ( 195 )

LIU Chang-zhao,WANG Ling,CHEN Wen-jiang,et al.

MicroRNAs( miRNA)is one of the key players in the gene expression regulatory network.It can regulate the gene expression of ion channel and participate in cardiac electrical remodeling,which is the important mechanism of the arrhythmia.To study the miRNA and cardiac electrical remodeling can help to clarify the mechanism of arrhythmia and open up a new way for the treatment of arrhythmia.This review article aims to provide a synopsis of the studies linking miRNA and cardiac electrical remodeling.

2015 Vol. 12 (18): 154-156 [Abstract]( 502 HTML (1 KB)  PDF  (717 KB)  ( 201 )

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