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中国医学创新

2015 Vol.12,No.28

Published 2016-10-05

WU Yue-hong,FU Yan-ji,PANG Liang-ming,et al.

Objective:To study the clinical significance of DSA-guided percutaneous nucleus pulposus clamp combined with ozone ablation in the treatment of cervical disc hermiation.Method:86 patients with cervical intervertebral disc hermiation of C4/5,C5/6,C6/7 or C7/T1 were selected as the research objects.43 patients with cervical intervertebral disc hermiation of C6/7 or C7/T1 in the clamp group(group A) were treated with DSA-guided percutaneous nucleus pulposus clamp combined with ozone ablation.43 patients with cervical intervertebral disc hermiation of C4/5 or C5/6 in the radio frequency group(group B) were treated with radiofrequency thermocoagulation combined with ozone ablation.The VAS scores and clinical effects in different stages of the two groups were observed and compared.Complications during and after the operation were recorded.Result:24 hours,72 hours,1 week,4 weeks and 12 weeks after the operation,the VAS scores of the two groups were lower than before treatment.4 weeks and 12 weeks after the operation, the VAS scores of group A were lower than those of group B.The differences above were all statistically significant(P<0.05).12 weeks after the operation,the excellent and good rate of group A was 91.3%,group B was 80.5%.The failure rate of group A was 8.7%,group B was 19.5%.There were no serious complications happened in the two groups.Conclusion:At present,DSA-guided percutaneous nucleus pulposus clamp combined with ozone ablation is the most safe and effective treatment method for cervical intervertebral disc herniation.

2015 Vol. 12 (28): 1-4 [Abstract]( 543 HTML (1 KB)  PDF  (724 KB)  ( 259 )

HOU Han.

Objective: To study the relationship between Galetin-3 and NYHA after acute myocardial infarction and the intervention function of atorvastatin on the NYHA patients with after acute myocardial infarction.Method: 100 patients with acute myocardial infarction in our hospital from May 2012 to May 2014 were randomly divided into observation group and control group, 50 cases in each group, and 50 health cases as health group. The observation group was treated with atorvastatin, and the control group was treated with common anti heart failure drugs.The intervention of the two groups was observed after acute myocardial infarction, and the Galetin-3 levels of all patients were detected. Result: The Galetin-3 levels significantly decreased after treatment in the two groups, but the patients in the observation group were significantly lower than those in the control ntrol group( P<0.05). There were no significant differences in cardiac function index between the two groups before treatment( P>0.05), after treatment, the heart function level of the two groups was significantly relieved than before treatment, the difference was statistically significant( P<0.05)). After treatment, inflammatory factors TNF-α, IL-6 and Hs-CRP levels of the two groups patients significantly decreased, the difference was statistically significant( P<0.05), and the observation group was significantly higher than that of the control group, the difference was statistically significant( P<0.05). The different NYHA levels of NT-proBNP when was grade Ⅰ,there was no difference before and after treatment( P>0.05), but significantly decreased in the other grade after treatment(P<0.05). Conclusion: Galetin-3 has a very important significance in predicting the occurrence of heart failure after acute myocardial infarction, and the effect of atorvastatin is more significant, which is worthy of clinical application.

2015 Vol. 12 (28): 5-7 [Abstract]( 729 HTML (1 KB)  PDF  (694 KB)  ( 224 )

WANG Jing-jing, ZHENG Ming-ping.

Objective: To investigate the application value of procalcitonin(PCT) and C-reactive protein(CRP) in the early diagnosis and treatment about the disease of infection in children. Method: 1268 children with infection in the pediatrics of our hospital from June 2012 to August 2014 were selected as the research objects.They were divided into two groups according to the results of pathogen and serum.The levels of PCT,CRP,WBC and ESR in the two groups were compared before and after treatment. Result: Before treatment the levels and positive rates of PCT and CRP in the bacterial infection group were significantly higher than those in the non-bacterial infection group,in the bacterial infection group,the positive rate of PCT was higher than the positive rate of CRP,the differences above were all statistically significant(P<0.05).The differences in the levels and positive rates of WBC and ESR in the two groups before treatment were not statistically significant(P>0.05). Conclusion: The levels of PCT and CRP increase significantly in children with infection, but PCT was superior to CRP in the early diagnosis of bacterial infection. The serum procalcitonin can accurately reflect the degree of infectious diseases, it has a good clinical application value in the diagnosis and prognosis of infectious diseases.

2015 Vol. 12 (28): 8-11 [Abstract]( 710 HTML (1 KB)  PDF  (715 KB)  ( 273 )

LI Jing-hua, LIU Hai-feng, HUANG Long-sheng, et al.

Objective: Minimally invasive treatment applied to benign cicatricial pyloric obstruction and duodenal stenosis patients, reduce trauma and complications, improve the quality of life. Method: In our hospital from September 2011 to June 2012 36 cases with the benign cicatricial pyloric obstruction and duodenal stenosis were treated with endoscopic balloon dilatation, and 32 patients were similar to baseline data for the same period surgical operation,all the patients were followed up to December 2014,and compared the prospective efficacy, complications and treatment cost. Result: The balloon dilation group endoscopy 2 weeks postoperatively in 36 patients, pyloric stenosis in patency in 29 cases, 7 cases with again after balloon dilation pyloric stenosis in patency, 1.19 times the average balloon dilatation.Among them 33 cases were markedly effective, effective in 3 cases, the total efficiency was 100%; after treatment

2015 Vol. 12 (28): 11-14 [Abstract]( 557 HTML (1 KB)  PDF  (713 KB)  ( 291 )

KUANG Zhong-shen, XU Hang, HUANG Zheng, et al.

Objective: To study the protective effects of calpain inhibitor calpeptin on the ischemic/reperfusion damage to the brain with the model of left middle cerebral artery ry occlution-reperfusion( MCAO) in rats. Method: Rats were randomly divided into four equal groups: group calpeptin, vector dimethyl sulfoxide( group DMSO), ischemic/reperfusion group( group MCAO), and sham operation group( group sham). After 2 hours of left middle cerebral artery(MCA) occlusion, followed by 12, 24 and 48 h of recirculation. After awakening from anesthesia, neurological functions of rats were evaluated with the 5 grade scale developed by Longa, Infarct zones were confirmed by TTCstaining, TUNEL was used to detect neuronal apoptosis in hippocampal CA1 section. Result: Compared with group MCAO rats, neurological functions and neuronal apoptosis of hippocampal CA1 section and infarct size of group DMSO had no significant difference.Neurological functions of group calpeptin had significant improvement; brain infarct size and neuron apoptosis of hippocampal CA1 section of group calpeptin were significant reduced. Conclusion: Calpeptin could significantly protect the brain against the ischemic/reperfusion damage in rats.

2015 Vol. 12 (28): 15-18 [Abstract]( 602 HTML (1 KB)  PDF  (715 KB)  ( 371 )

CHEN Xiao-juan,XIAO Zong-yu,PAN Qi,et al.

Objective:To isolate,culture and identify the bone marrow mesenchymal stem cells-derived neural stem cells(BMSCs-NSCs) in order to observe their growth pattern and differentiation features.Method:Bone marrow mesenchymal stem cells of the Wistar rats were cultured in serum-free medium.Floating neural spheres were formed in serum-free medium,the expression of CD133 and Nestin in the neural spheres was tested by immunohistochemistry.Then floating neural spheres were transferred into serum containing medium for induction differentiation,the expression of GFAP,Map2,β-tubulin Ⅲ and Galc were detected by immunocytochemistry 7 days later. Result:Bone marrow mesenchymal stem cells lived in serum-free medium‘ floating’ and it formed neural sphere.CD133 and Nestin were positive in neural sphere cells according to the results of immunohistochemistry. When these neural sphere cells were transferred into serum-containing medium,they grew adhering to the wall.GFAPMAP-2,β-tubulin Ⅲ and Galc were positive in the cells differentiated from neural spheres. Conclusion:Bone marrow mesenchymal stem cells-derived neural stem cells which growing like a ball and having multipotential differentiation are successfully cultured in serum-free medium with bFGF and EGF.

2015 Vol. 12 (28): 18-22 [Abstract]( 609 HTML (1 KB)  PDF  (1178 KB)  ( 286 )

LIANG Dong-yong, HUANG Yue, LI Qu, et al.

Objective: To discuss the clinical effect of endoscopic sinus inferior turbinate boning and mucosa scratches minimally invasive volume reduction surgery to cure chronic hypertrophic rhinitis. Method: 90 patients with the clinical diagnosis of chronic hypertrophic rhinitis were randomly divided into two groups: the experiment group contained 45 cases accepted the inferior turbinate boning and mucosa scratches minimally invasive volume reduction surgery;the control group contained 45 cases accepted the operation of partial inferior turbinectomy. For a comparative analysis, they were observed for 6 months for clinical results and postoperative complications after operation. Then the saccharin test was carried out. The nasal mucociliary function at 3 months after operation and 6 months after operation was compared. Result: The difference of the clinical effect between the two groups was not statistically significant( P>0.05); the occurrence rate of operative complication of the experiment group was significantly lower than that of the control group( P<0.05); the mucociliary transport rate( MTR) of the experiment group, before the operation and 3 months after operation and 6 months after operation, had no obviously changes( P>0.05), but that of the control group was obviously lower than pre-operation(on average, P<0.01). The MTR of the control group was lower than that of the experiment group at 3 months after operation and 6 months after operation( P<0.01). Conclusion: Endoscopic sinus inferior turbinate boning and mucosa scratches minimally invasive volume reduction surgery is effective. It has fewer complications, which keeps the function of nasal mucosa and is consistent with clinical physiological function, so it is recommended.

2015 Vol. 12 (28): 23-25 [Abstract]( 551 HTML (1 KB)  PDF  (707 KB)  ( 208 )

DENG Liang, LI Shu-fang, LAO Wu-jian.

Objective: To investigate the relationship between the long-term using of proton pump inhibitors and gastric mucosa atrophy and intestinal metaplasia. Method: Outpatient and hospitalized patients met the inclusion criteria in Department of internal medicine in our hospital were divided into two groups randomly, experimental group contained 44 patients, control group 24 patients. Two groups were performed in 14C breath test and gastroscopy and biopsy. The experimental group was treated by proton pump inhibitors for acid suppression therapy, the control group without intervention, in experiment 6, 12, 24 months were performed 14C carbon breath test and gastroscopy and biopsy.Result: The Helicobacter pylori positive patients were 19, 5, 3, 12 cases in the experimental group at 0, 6, 12, 24 months, in the control group were 10, 2, 2, 5 cases respectively. The two groups Helicobacter pylori infection rate had no statistically significant difference at 0, 6, 12, 24 months. The experimental group in 6 months found 7 cases with intestinal metaplasia, and 1 case with atrophic gastritis. In 12 months found 9 cases with intestinal metaplasia, and 1 case with atrophic gastritis. In 24 months found 15 cases with intestinal metaplasia, and 2 cases with atrophic gastritis. The control group in 6 months found 2 cases with intestinal metaplasia. In 12 months found 2 cases with intestinal metaplasia. In 24 months found 4 cases with intestinal metaplasia and 1 case with atrophic gastritis. In 6, 12, 24 months, there was no significant difference of atrophic gastritis and intestinal metaplasia between the two groups. Conclusion: The results of the research suggested that, long-term use of proton pump inhibitors with atrophic gastritis and intestinal metaplasia occurs has no statistically significant correlation, but has the possibility of leads to intestinal metaplasia. So suggest the patients need regular endoscopic examination and Helicobacter pylori infection test which long-term uses the proton pump inhibitors.

2015 Vol. 12 (28): 26-28 [Abstract]( 658 HTML (1 KB)  PDF  (692 KB)  ( 271 )

FANG Zhi-wei.

Objective: To observe the relationship between hypertensive intracerebral hemorrhage timing and manner of operation and efficacy. Method: 150 patients with hypertensive intracerebral hemorrhage in our hospital from June 2011 to June 2013 were selected, according to the patients with different time from onset to surgery were divided into A, B, C three groups, A group contained 50 patients , bleeding less than 7 h, 40 patients in group B, bleeding time between 7-24 h, 50 patients in group C, bleeding time greater than 24h. Depending on the amount of bleeding in patients with a bleeding site and choose craniotomy, burr hole surgery and small bone window craniotomy and other surgical procedures, observe and compare the efficacy and prognosis of patients. Result: Group A total effective rate was 92.00%( 46/50) was significantly higher than 75.00%( 30/40) in group B and 50.00%( 25/50) in group C( P<0.05);and group B was significantly higher than group C( P<0.05); A group improvement rate was 88.00%( 44/50), which was significantly higher than 70.00%( 28/40) in group B and 36%( 18/50) in group C( P<0.05); improvement rate of group B was significantly higher than group C( P<0.05); A group mortality was 2.00%( 1/50 ), which was significantly lower than 7.50%( 3/40) in group B and 16%( 8/50) in group C( P<0.05); mortality in group B was significantly lower than in group C( P<0.05). Conclusion: The timing of surgery and the surgical approach has an important impact on the treatment and prognosis of patients with hypertensive intracerebral hemorrhage.

2015 Vol. 12 (28): 29-31 [Abstract]( 590 HTML (1 KB)  PDF  (692 KB)  ( 239 )

LIU Jian-jun, MIN Zhi-rong, XIE Jing-bo, et al.

Objective: To compare the clinical effect of minimally invasive percutaneous plate osteosynthesis(MIPPO) and open reduction and internal fixation( ORIF) in the treatment of distal tibial fracture. Method: 60 patients with distal tibial fracture treated in our hospital from May 2012 to May 2014 were selected and divided into ORIF group and MIPPO group with 30 cases in each group, who were treated by ORIF and MIPPO respectively, the clinical efficacy was compared between the two groups.Result: There was no significant statistical difference between the two groups in hospitalization. Operation time, length of incision, fracture recovery time of the MIPPO group was shorter than that of the ORIF group, blood loss was less, excellent and good rate of the clinical efficacy was higher, the incidence of complication was lower, the differences were statistically significant( P<0.05). Conclusion: Both MIPPO and ORIF are safe and effective procedures for fixation of distal tibia fracture, while MIPPO is advantageous with less bleeding, shorter operation time, lower complication, rapid postoperative recovery, better clinical efficacy in treating distal tibia fracture compared with ORIF, which worthy of better being studied and promoted in clinic.

2015 Vol. 12 (28): 32-34 [Abstract]( 594 HTML (1 KB)  PDF  (692 KB)  ( 241 )

LIANG Jun-ming,ZENG Kuan, LUO Xue-mei.

Objective: To study the expression of VEGF and SSTR and their correlations in patients with gastric cancer. Method: 90 patients with gastric cancer treated from January 2010 to December 2014 in our hospital were selected as gastric cancer group and 60 healthy check-ups were selected as control group. Through
immunohistochemistry staining methods, the expression of VEGF and SSTR in different gastric mucosa tissues were detected. Result: The positive rate of VEFG in gastric cancer group was 62.2%( 56 cases); the positive rate of VEGF in the control group was 8.3%( 5 cases)( P<0.05); the gastric cancer group contained 73 positive cases in SSTR1( 81.1%), 67 positive cases in SSTR2( 74.4%) and 47 positive cases in SSTR3( 52.2%); the control group contained 47 positive cases in SSTR1( 78.3%), 56 positive cases in SSTR2( 93.3%) and 51 positive cases in SSTR3(85.5%); the positive expression of SSTR1 of the two groups was not significantly different( P>0.05); the positive rate of SSTR2 and SSTR3 of the gastric cancer group was lower than that of the control group( P<0.05). VEGF expression was significantly correlated with SSTR2 and SSTR3 expression in gastric cancer tissues( P<0.05); VEGF expression was not closely correlated with SSTR1 expression( P>0.05). Conclusion: VEGF is highly expressed while SSTR is lowly expressed in gastric cancer tissues. VEGF is negatively correlated with SSTR, which indicates that the up-regulation of VEGF during signal transduction of occurrence and development of gastric cancer will cause the loss of SSTR.

2015 Vol. 12 (28): 35-37 [Abstract]( 724 HTML (1 KB)  PDF  (693 KB)  ( 310 )

XIE Chuan-hua.

Objective:To observe the clinical effect of Sapylin inhalation combined with NP regimen for the treatment of advanced non-small cell lung cancer and its effects on the T lymphocyte subsets.Method:68 cases of advanced non-small cell lung cancer in our hospital were selected,they were randomly divided into inhalation combined with NP regimen group( O-NP group) and NP regimen alone group( NP group), 34 cases in each group. The clinical efficacy of the two groups after treatment and the level of T cells subsets before and after treatment were compared.Result:The clinical effect of O-NP group was significantly better than that of NP group,the difference was statistically significant(P<0.05).In O-NP group,the T cells subgroup level after treatment was significantly better than before,and it was also significantly better than that in NP group,the differences were statistically significant(P<0.05).Conclusion:Sapylin inhalation combined with NP regimen for the treatment of advanced non-small cell lung cancer is effective,can effectively improve the immune function,it is worthy of clinical application.

2015 Vol. 12 (28): 38-40 [Abstract]( 498 HTML (1 KB)  PDF  (707 KB)  ( 306 )

PU Na, ZHANG Cai-ping, GAO Yan-guo.

Objective: To observe the clinical effect of continuous renal replacement therapy on treating acute renal failure of severe patients. Method: 56 patients achieved ARF treatment in our hospital from January 2012 to June 2014 were selected, they were divided into control group and treatment group, 28 cases in each group, the treatment group was treated with continuous renal replacement scheme, and the control group used intermittent renal replacement therapy program, to observe BUN, Scr, changes of laboratory index, survival rate and occurrence of complications before treatment and after 4 weeks of treatment of the two groups. Result: After 4 weeks , BUN, Scr of the two groups significantly decreased than before treatment, and the treatment group was more obvious than the control group, with statistical significance( P<0.05). There were 5 patients occurred complications in the treatment group, the incidence rate was 17.86%, and there were 15 cases in the control group, the incidence was 53.57%. Treatment group’s incidence was significantly lower than that of the control group, with statistical significance( P<0.05). There were 4 cases died in the treatment group, the mortality rate was 14.29%, 12 cases died in the control group, the fatality rate was 42.86%,mortality rates of treatment group was significantly lower than that of the control group, with statistical difference( P<0.05). Conclusion: The effect of continuous renal replacement therapy is reliable on treatment of acute renal failure, it is worth
the clinical promotion.

2015 Vol. 12 (28): 40-42 [Abstract]( 648 HTML (1 KB)  PDF  (704 KB)  ( 190 )

LIN Yan-yan.

Objective:To discuss the application value of rehabilitation training guidance in stroke patients with hemiplegia rehabilitation exercise.Method:60 stroke patients with hemiplegia were selected from March 2013 to June 2014 in our hospital,all patients were randomly divided into guide group and control group,30 cases in each group.Two groups were given routine rehabilitation exercise intervention, the guide group was given rehabilitation training guidance
on the basis of that .Fugl-Meyer rating method( FM) was used to evaluate the balance function in patients,Modified Barthel index( MBI) was used to assess patients life ability, followed up for 6 months, all patients rehabilitation training exercises target rate,the balance function and life ability before treatment and after treatment of 2,4 and 6 months were analysed.Result:The rehabilitation training exercises target rate of guide group was 93.33% ,control group was 66.67% ,the former was higher than the later,the difference was statistically significant(P<0.05).Before the treatment, FM and MBI score of two groups compared, the difference was no statistically significant(P>0.05).After treatment 2,4 and 6 months,the FM and MBI score of guide group were better than control group, the differences were statistically significant(P<0.05).Conclusion:Rehabilitation guidance training can effectively improve the operation success rate, cerebral stroke patients with hemiplegia rehabilitation training to improve the effect of rehabilitation exercise, balance function in
patients with continuous improvement and life skills,it’s worth for further clinical promotion.

2015 Vol. 12 (28): 43-46 [Abstract]( 472 HTML (1 KB)  PDF  (726 KB)  ( 354 )

ZOU Ting.

Objective: To study the clinical effect of continuous blood purification scheme for patients in ICU with hypernatremia disease s.Method: 88 patients in ICU with hypernatremia disease in our hospital were randomly divided into control group and treatment group,44 cases in each group. The control group was given conventional conservative treatment options,the treatment group was used continuous blood purification scheme.After treatment,the observation indexes of two groups were compared. Result:The effect of ICU patients with hypernatremia disease in treatment group was better than the control group,hypernatremia symptoms disappear time,received ICU treatment time, and total hospitalization time of treatment group were significantly shorter than the control group,the differences were statistically significant(P<0.05).Conclusion: The clinical effect of continuous blood purification program for patients suffering from ICU with hypernatremia disease is very obvious,it is worth to promote in clinical.

2015 Vol. 12 (28): 46-48 [Abstract]( 635 HTML (1 KB)  PDF  (692 KB)  ( 296 )

LYU Hua-liang,CHEN Chun-jie,MAI Qian-ting,et al.

Objective:To compare the effect of nasal mask and mask connected noninvasive ventilation with bilevel positive airway pressure(BiPAP) in the rescue of type Ⅱ respiratory failure and to explore the better noninvasive ventilation connection mode.Method:80 patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD) combined with type II respiratory failure in our hospital from September 2013 to November 2014 were selected and randomly divided into two groups.All patients were given the basic treatment of anti infection,eliminating phlegm,relieving cough,spasmolysis,relieving asthma and respiratory stimulant.The two groups were given noninvasive ventilation with BiPAP on the basis of the basic treatment.The observation group was given nasal mask connection noninvasive ventilation and the control group was given mask connection noninvasive ventilation.The vital signs,indexes of blood gas,compliance rate,success rate, intubation rate,days of hospitalization and mortality rate of the two groups were observed and compared.Result:After ventilation,the vital signs and indexes of blood gas of the two groups were better than before ventilation.3 hours after the ventilation,the respiratory rate(R),oxygen saturation(SpO2) and indexes of blood gas in the control group were better than those in the observation group.The compliance rate and success rate of the observation group were higher than those of the control group.The differences above were all statistically significant(P<0.05).The differences in the intubation rate,days of hospitalization and mortality rate of the two groups were not statistically significant(P>0.05).Conclusion:The effect of nasal mask and mask connection noninvasive ventilation with BiPAP in the treatment of AECOPD complicated with type Ⅱ respiratory failure is significant. The improvement of R,SpO2 and indexes of blood gas in patients with mask connection is faster than that in patients with nasal mask connection.But there is no significant difference in terms of the effect between the two connection methods after 12 hours of ventilation.Nasal mask connection is better in comfortability,compliance and the success rate,it is easier for clinical application.

2015 Vol. 12 (28): 49-52 [Abstract]( 439 HTML (1 KB)  PDF  (715 KB)  ( 243 )

CHEN Ting-gang,LONG Hang,CHEN Shi-jiu,et al.

Objective:To probe into the clinical efficacy regarding restoration of distal tibial vascular injurybased composite tissue defects by bridge-crossing with free latissimus dorsi flaps.Method:Nine patients with distal vascular injury-based composite tissue defects in our hospital from April 2011 to February 2015 were selected as the research objects.They were treated by bridge-crossing with free latissimus dorsi flaps.Result:The pedicles were cut off 4 weeks after the operation.All patients got follow-up from 6 months to 24 months. All the flaps survived with satisfactory appearance,color and texture,and the injured limbs regained weight-bearing capacity.Conclusion:The bridgecrossing method with free latissimus dorsi flaps is ideal for restoration of distal vascular injury-based composite tissue defects with wide cutting ranges,reliable blood supply,improved local blood circulation in recipient areas,as well as zero damage to blood vessels in injured limbs,which can help establish blood supply between the flaps and the recipient areas.

2015 Vol. 12 (28): 52-55 [Abstract]( 443 HTML (1 KB)  PDF  (913 KB)  ( 200 )

WU Hong,YIN Yu-qian,ZHAO Chun-ning.

Objective:To study the effect of the applying of compound tropicamide eye drops in refractive inspection of children with myopia.Method:56 cases(112 eyes)myopia children aged from 7 to 17 years were grouped as group 7-12 years and 13-18 years.The refractive capacity of the eye was examined with a computer and a retinoscopy by skilled optometrist before and after mydriasis. The differences of the values of spherical equivalence(SE)before and after mydriasis were analyzed with SPSS 17.0 in every group.Result:There were no significant differences in the values of SE before and after mydriasis in each group(P>0.05).Conclusion:Compound tropicamide eye drops is a cycloplegic agent.But its effects are limited for children with different age.

2015 Vol. 12 (28): 56-59 [Abstract]( 522 HTML (1 KB)  PDF  (713 KB)  ( 937 )

ZHAO Hong,HUANG Hua,BO Tao,et al.

Objective: To investigate the incidence and treatment of depression and cognition in young adult patients after stroke.Method:80 young adult patients with stroke in our hospital from March 2003 to May 2013 were selected and randomly divided into two groups.Forty patients in the treatment group were treated with drugs and psychotherapy for eight weeks,forty patients in the control group were not given the treatment above.All patients were measured with Zung scale,HAMD,MMSE and Scandinavian Stroke Scale(SSS) before and after treatment.Result:The incidence rate of depression and cognition was 40.00%.Literacy and neurological deficits had a relationship with the occurrence of depression and cognition.After treatment,the Zung scores,HAMD scores and SSS scores of the treatment group were lower than those before treatment and those of the control group,the differences were statistically significant(P<0.01).Conclusion: The incidence rate of depression and cognition is high,it may be caused by biology-psychology-social factors. Comprehensive treatment has important significance in the treatment of depression and cognition in young adult patients after stroke.

2015 Vol. 12 (28): 59-62 [Abstract]( 608 HTML (1 KB)  PDF  (713 KB)  ( 266 )

ZHAO Ping-ping, CHEN Ling, FAN Yi-bing,et al.

Objective: To measure the level of oral health and evaluate the effect of oral invention of rural households in Nanchang city, Jiangxi province. Method:Simple random sampling was taken. 729 residents from 200 rural households were assigned to fill in the questionnaires designed by the national health and family planning commission before and after carrying out oral invention. Result: Before carrying out the oral invention, the rate of caries,caries filling and using fluoride toothpaste was 1.68%, 10.56% and 26.90%, separately. After carrying out the oral invention, oral health knowledge, attitudes, behavior and the rate of caries filling improved significantly( P<0.05).Conclusion: We need not only to strengthen the propaganda and education about oral health in rural community, but also to carry on intervention to decrease the dangerous behavior of rural residents.

2015 Vol. 12 (28): 63-66 [Abstract]( 517 HTML (1 KB)  PDF  (713 KB)  ( 160 )

HU Hong-yan,LIN Xiao-jie,WEN Yan,et al.

Objective:To investigate the prevalence of major chronic diseases and nutritional status of elderly health examination population in order to provide scientific basis for improving the health status of the elderly. Method:Elderly health examination people in our hospital from September 2011 to December 2014 were selected as the research objects.Self designed questionnaire and Mini Nutritional Assessment(MNA) were used to survey the research objects.Result:In the 877 examination people,there were 114(13.0%) people without any diseases,405(46.2%) people suffering from one kind of disease,221(25.2%) people suffering from two kinds of diseases and 137(15.6%) people suffering from three or more kinds of diseases.There were 481(54.8%) people with hypertension,203(23.1%) people with coronary heart disease and 153(17.4%) people with diabetes mellitus,the diseases above were the first three diseases according to their morbidity rates.The first three diseases according to the medication compliance were chronic obstructive pulmonary disease(81.8%),hypertension(81.7%) and pneumonia( 81.0%).The average MNA total score was( 23.1±3.9).In the research objects,there were 416(47.4%) people with potential malnutrition and 48(5.5%) people with malnutrition. Comparing the MNA scores of the elderly in different financial situation and different teeth situation respectively,the differences were statistically significant(P<0.05).Conclusion:Most of the elderly population are associated with one or more chronic diseases and there are also a certain number of undernourished people. The relevant departments should attach importance to the nutrition and health education of the elderly and actively improve the nutritional status of the old.

2015 Vol. 12 (28): 66-69 [Abstract]( 582 HTML (1 KB)  PDF  (722 KB)  ( 250 )

HE Qing-qin.

Objective:To explore the influence of diet and psychological nursing on quality of life and psychological state of senile breast cancer patients with chemotherapy. Method:The clinical data of 210 patients with breast cancer in our hospital from January 2012 to December 2013 were retrospectively analyzed.They were divided into the control group and the observation group according to different nursing models.100 patients in the control group were given conventional nursing during chemotherapy period,110 patients in the observation group were given diet and psychological nursing intervention on the basis of conventional nursing.The psychological status and quality of life were compared between the two groups before and after the intervention. Result:After the intervention,the score of quality of life in the observation group was higher than before the observation and higher than that of the control group,the total average score of SCL-90 and the score of each factor in the observation group were lower than before the observation and lower than those in the control group,the differences above were statistically significant(P<0.05). Conclusion:Diet and psychological nursing intervention in senile patients with breast cancer during the treatment of chemotherapy can significantly improve patients’ quality of life and their psychological status.It is worthy of clinical promotion.

2015 Vol. 12 (28): 70-72 [Abstract]( 635 HTML (1 KB)  PDF  (691 KB)  ( 322 )

ZHONG Li-juan,ZHONG Li-qiong,ZHENG Li-fang.

Objective:To investigate the application of detailed nursing in the manipulation combined with herbal fumigation treatment for children with humeral supracondylar fracture of Gartland type Ⅱ,Ⅲ.Method:80 cases of children with humeral supracondylar fracture of Gartland type Ⅱ,Ⅲ in our hospital from May 2013 to May 2014 were selected and randomly divided into the interventional group and the control group,with each group 40 cases.All patients accepted the treatment of manipulation combined with herbal fumigation.Children in the control group were given routine nursing of orthopedics,the interventional group was given detailed nursing on the basis of the control group.The pain degree,the cooperation degree of manipulation reduction,the incidence of postoperative complications and the situation of parents' satisfaction and nursing standards were observed and compared between the two groups.Result:The OPS score and the cooperation degree of manipulation reduction in the interventional group were higher than those in the control group,the differences were statistically significant(P<0.05).The incidence of postoperative complications and the situation of parents' satisfaction and nursing standards in the interventional group were better than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Detailed nursing can effectively reduce the pain degree of children with humeral supracondylar fracture of Gartland type Ⅱ,Ⅲ,improve the cooperation of manipulation reduction,reduce the incidence of postoperative complications and improve the satisfaction of parents.It can be widely applied to clinic.

2015 Vol. 12 (28): 73-76 [Abstract]( 529 HTML (1 KB)  PDF  (726 KB)  ( 183 )

GONG Yan.

Objective: To study the targeted nursing for the psychological state of patients with chronic gastric ulcer and affect the quality of life. Method: From January 2013 to September 2014 in our hospital admission for treatment of 42 patients with chronic gastric ulcer. They were randomly divided into observation group and control group, 21 cases in each group. The observation group accepted targeted nursing, the control group received the routine psychological nursing, to compare psychological status and quality of life of the two groups before and after nursing. Result: 42 patients with psychological questionnaire survey result showed that, after nursing, all kinds of psychological problems could be alleviated, but the patients in the observation group became more pronounced. The results of the observation group was significantly better, its advantages and patients accounted for 71.43%, the excellent and good rate was as high as 95.24%,which was higher than 23.81%, 61.90% of the control group. After nursing, the observation group all aspects of functional scores were higher than those of the control group, with significant differences( P<0.05). Conclusion: The clinical effect of targeted nursing for patients with chronic gastric ulcer is far superior to conventional nursing effect, can promote the recovery of patients, improve the patient’s quality of life.

2015 Vol. 12 (28): 76-78 [Abstract]( 707 HTML (1 KB)  PDF  (704 KB)  ( 203 )

LIU Qiao-er,CAO Quan-ying,CHEN Miao-ling,et al.

Objective:To explore the clinical application in the early rehabilitation nursing mode of stroke patients with hemiplegia.Method:82 stroke patients were selected in our home community health center from January 2013 to January 2014,they were divided into the control group and the treatment group,41 cases in each group.The control group was given routine care,on the basis of that treatment group was given early nursing rehabilitation nursing mode,the nursing effect of the two groups were analyzed.Result:The treatment group was treated with early rehabilitation nursing model of care intervention after the treatment, the total effective rate was 97.6%, which was significantly higher than only conventional model of care nursing intervention in the control group(80.5%),the difference was statistically significant(P<0.05).The nursing satisfaction of treatment group was 95.1%, which was significantly higher than 75.6% of control group,the difference was statistically significant(P<0.05).Before nursing intervention,compared the easy to carry out motor function score and quality of life score of two groups, the differences were no statistically significant(P>0.05).After nursing intervention, the easy to carry out motor function score and quality of life score of two groups were improved,but the treatment group were significantly better than the control group,the differences were statistically significant(P<0.05). Conclusion:Early rehabilitation nursing intervention can improve hemiplegic stroke patients’ paralyzed limb function, reduce morbidity and improve quality of life,it helps to improve patients’ satisfaction with nursing care.

2015 Vol. 12 (28): 79-82 [Abstract]( 579 HTML (1 KB)  PDF  (726 KB)  ( 307 )

ZHANG Xiu-bo.

Objective: To explore the effect of root cause analysis( RCA) in reducing the incident of urine retention after catheter removal among patients with indwelling catheter. Method: RCA group was established,the related data were collected,the fishbone diagram was used to identify the immediate causes of the incident of urine retention after catheter removal,the root causes were determined, then improvement measures were developed and implemented, and the effects before and after the application of RCA were compared. Result: After implementation the method of RCA,the incidence of urine retention after catheter removal among patients with indwelling catheter decreased from 17.65% to 6.37%,the patients’ satisfaction improved from 83.33% to 94.55%,the difference was statistically significant(P<0.05). Conclusion:The application of RCA can effectively reduce the incidence of urine retention after catheter removal among patients with indwelling catheter, improve the quality of nursing and patients’ satisfaction and promote the development of the group members.

2015 Vol. 12 (28): 82-85 [Abstract]( 563 HTML (1 KB)  PDF  (800 KB)  ( 336 )

ZENG Xin-hua,OUYANG Yan,LAI Hui-hong.

Objective: To investigate the effects of developmental care on the growth and development of premature infants.Method:200 cases of premature infants in our hospital from March 2011 to March 2014 were selected and randomly divided into the observation group and the control group,with each group 100 cases.The control group was given routine nursing,the observation group was given developmental care on the basis of routine nursing.The secretory volume of gastrin,the situation of growth and development,the occurrence of feeding intolerance and parents satisfaction of the two groups were observed and compared.Result:2 and 3 months after the nursing,the secretory volumes of gastrin in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).After the nursing,the weight,the height,the occurrence of feeding intolerance and parents satisfaction in the observation group were better than those in the control group,the differences were statistically significant(P<0.05). Conclusion:Developmental care used in premature infants can promote the secretory of gastrin,reduce the occurrence of feeding intolerance and improve parents satisfaction.It is good for premature infants’ growth and development and it is worthy of clinical application.

2015 Vol. 12 (28): 86-89 [Abstract]( 548 HTML (1 KB)  PDF  (713 KB)  ( 265 )

JING Ke-feng,ZHANG Wen-guang,YANG Hui,et al.

Objective:To search an executive ability evaluation system for head nurses. Method:Evaluation index system was established by Delphi method together with suggestions from experts in two rounds, the optimal sequence diagram method was used to determine the weights of the first level index, the expert evaluation method was used to determine the weights of the second level index.Result:The index system established comprised two levels: with 8 indexes of the first level index( task decomposition ability,understanding of mission ability, authorization ability, process control ability,communication ability, learning and innovation ability, responsibility of execution and evaluation ability) and 41 others on the second level index and the value coefficient was given to each index.Conclusion:The results of two rounds’ expert consultation with the reliability of the index system constructed from multiple dimensions reflect the characteristics of executive ability for head nurses and offer a objective assessment for head nurses.

2015 Vol. 12 (28): 89-92 [Abstract]( 686 HTML (1 KB)  PDF  (720 KB)  ( 223 )

LI Xiao-hua,MAN Jie, CHEN Wei-jun.

Objective: To analyze the clinical curative effect of Xiaoyin granule in the treatment of measles. Method: From 2011 June to 2013 February, 87 urticaria patients in our hospital were selected as research objects,according to different treatments, they were randomly divided into two groups, control group contained 42 cases, received cetirizine tablets, 45 cases in the treatment group, based on the control group received cetirizine tablets plus Xiaoyin granules, the therapeutic effect were compared between the two groups after treatment. Result: The treatment group total effective rate was 97.8%, the control group was 78.6%, the treatment group was significantly higher than that of the control group, the differences between the two groups was significant( P<0.05). The score of the patients before treatment of urticaria symptoms had no significant difference, after treatment, the two groups improved, but the treatment group urticaria symptoms score was significantly better than that of the control group( P<0.05), there was statistical significance. The occurrence and adverse reaction of the treatment group was significantly lower than that of the control group, there was a significant difference( P<0.05). Conclusion: Xiaoyin granules in the treatment of urticaria can be achieved significant results, which has important value in patients with recurrent and reduce adverse reactions, improve the therapeutic effect,improvement of the symptoms integral, can be widely applied in clinical practice.

2015 Vol. 12 (28): 93-95 [Abstract]( 863 HTML (1 KB)  PDF  (693 KB)  ( 441 )

HAN Jian-xin.

Objective: To observe the clinical curative effect of Yiqi huoxue method to treat arrhythmia. Method: From August 2013 to August 2014, 50 patients with arrhythmia, were randomly divided into treatment group and control group, the control group used conventional drug treatment process of atropine, the treatment group was treated by yiqi huoxue method implementation process, to compare the clinical efficacy of the two groups and the incidence of adverse reactions. Result: The treatment group total effective rate was 92.00%, the control group was 72.00%. And implement different after treatment, the treatment group patients’ whole blood viscosity( high), whole blood viscosity(low shear), plasma viscosity ratio, red blood cells deposited, indexes of blood sedimentation six RBC electrophoresis was( 3.14±1.22),( 6.50±1.18),( 1.52±0.20),( 38.38±3.20)%,( 25.08±2.23)s and( 11.39±6.12)mm/h, and the control group changed significantly, there was significant difference between the two groups( P<0.05). Conclusion: Arrhythmia is treated by yiqi huoxue method to carry out the treatment process, the treatment effect is more pronounced, less adverse drug reaction, at the same time to improve the blood rheology indexes and cardiac function in patients with the indicators the result has a significant effect, is worth popularizing in clinical application.

2015 Vol. 12 (28): 96-98 [Abstract]( 599 HTML (1 KB)  PDF  (691 KB)  ( 194 )

DENG Chun-qing,FENG Shan-shan.

Objective:To extract human genomic DNA with HBV infection,and preparation of DNA template for studying the genetic polymorphism of HBV infection.Method:HBV infection of human anticoagulant whole blood were collected,Human genomic DNA was extracted by Miller’s Method.Result:DNA template in HBV infected person included asymptomatic carrier,chronic hepatitis,severe hepatitis,liver cirrhosis and hepatocellular carcinoma,and part of a healthy blood donors were collected at the same time.Conclusion: The template library is mainly HBV persistent infection,extracted DNA with Miller’s Method has high purity and stability.

2015 Vol. 12 (28): 99-101 [Abstract]( 542 HTML (1 KB)  PDF  (854 KB)  ( 168 )

XU Gu-gen,YIN Zhuo-na,YANG Xiao-chun,et al.

Objective:To explore the significance of remote wireless glucose monitoring system applied in patients with diabetes of community.Method:120 patients were randomly divided into the treatment group and the control group,with each group 60 cases.The treatment group was given remote wireless glucose monitoring system to monitoring the blood glucose.The control group was treated and observed according to patients’ living habit.The body mass index,fasting blood glucose,postprandial 2 hours blood glucose,glycosylated hemoglobin,blood lipid profiles and hypoglycemia situation were observed before and after treatment. Result:6 months and 1 year after the observation,the FBG,2 h PG,HbA1c,TC,TG,LDL,HDL and hypoglycemia situation of the treatment group were better than those of the control group,the differences were statistically significant(P<0.05).1 year after the observation,the BMI of the treatment group was better than that of the control group,the difference was statistically significant(P<0.05).6 months after the observation,the FBG,2 h PG,HbA1c,TC,TG,LDL and HDL of the treatment group were better than before,while the 2 h PG and LDL of the control group were higher than before.1 year after the observation,the BMI,FBG,2 h PG,HbA1c,TC,TG,LDL and HDL of the treatment group were better than before,while the HbA1c,2 h PG,TG and LDL of the control group were higher than before.Conclusion:The remote wireless blood glucose monitoring system can improve the control of blood glucose,blood lipid and body weight in community diabetic patients,it can also reduce the occurrence of hypoglycemia.

2015 Vol. 12 (28): 102-106 [Abstract]( 578 HTML (1 KB)  PDF  (765 KB)  ( 264 )

ZHOU Hua-jiao,YUE Hong,WANG Ming-xi,et al.

Objective:To discuss whether oxytocin can be applied to full-term pregnancy induced labor after cesarean. Method:842 pregnant women after cesarean section and again pregnancy were collected from February 2012 to March 2014 in our hospital, the clinical effect of oxytocin was observed, its security was analyzed. Result:The uterine scar group accepted oxytocin treatment,its postpartum hemorrhage occurred in 3 cases, the rate was 6.52%,nonpuerperal infection,no newborns was transferred to NICU,hospital stay were 2 to 9 days,the average were(4.24±2.05) days,compared with non-uterine scar group, the difference was no statistically significant(P<0.05). Conclusion:Oxytocin induction of labor at term of pregnancy after cesarean are feasible and relatively safe.

2015 Vol. 12 (28): 106-109 [Abstract]( 671 HTML (1 KB)  PDF  (712 KB)  ( 398 )

YANG Pu, YANG Jing-xin, XIE Chu-neng.

Objective: To investigate the effect and possible mechanism of lanthanum carbonate on vascular calcification in dialysis patients. Method: 30 regular hemodialysis patients( dialysis for at least 3 months) admitted to our hospital from January 2013 to August 2014 as the research objects, and were given the lanthanum carbonate treatment for 12 weeks, to compare iPTH( serum intact parathyroid hormone), FGF23( fibroblast growth factor 23), 25(OH)D( serum 25 hydroxy vitamin D) and other indicators level before and after treatment of patients. In addition, to take calcium carbonate for 1 month after disable lanthanum carbonate, and compare the index level of the two groups. Result: The serum phosphate before and after lanthanum carbonate treatment between the two groups,the difference was statistically significant( P<0.05). In addition, lanthanum carbonate, calcium carbonate treatment for 1 month after the patients blood phosphorus,the differences were significant( P<0.05). In addition, the incidence of adverse reactions was 20.00%
during the lanthanum carbonate treatment. Conclusion: Lanthanum carbonate has an important role in the treatment of dialysis patients with hyperphosphatemia, prevent to vascular calcification, and lanthanum carbonate may be through the reduction of FGF23 and blood phosphorus level to achieve the purpose of prevention of vascular calcification.

2015 Vol. 12 (28): 110-112 [Abstract]( 644 HTML (1 KB)  PDF  (693 KB)  ( 208 )

CAO Yuan-yuan,YANG Qian,ZHAO Xia,et al.

Objective:To study the application of bedside continuous renal replacement therapy(CRRT) in acute renal failure after cardiac surgery.Method:The clinical data of 30 patients who occurred acute renal failure after cardiac surgery in our hospital from November 2012 to November 2014 were retrospectively analyzed.All patients were given bedside CRRT on the basis of routine treatment.The treatment results,the cardiac function and the renal function before and after the treatment were observed.Result:Among the 30 patients,26 cases survived and 4 cases died.In the 26 survival patients,23 patients were recovery and 3 patients were effective.The total effective rate was 86.67%.CRRT was applied in 2 to 24 hours after the operation,it was continuously applied for more than 24 hours,the mean time was (68.7±6.2) hours.The cardiac index(CI),heart rate(HR),mean arterial pressure(MAP),pulmonary capillary wedge pressure(PCWP),central venous pressure(CVP),oxygen saturation(SpO2),left ventricular ejection fraction(LVEF),oxygenation index(PaO2/FiO2),blood urea nitrogen(BUN),creatinine(Cr),HCO3 - in blood,serum potassium and urine volume after treatment were better than before treatment,the differences were statistically significant(P<0.05).Conclusion:Bedside CRRT in patients with acute renal failure after cardiac surgery can effectively reduce the mortality rate and improve heart function and renal function.The curative effect of the treatment is remarkable and it has positive clinical significance.

2015 Vol. 12 (28): 115-117 [Abstract]( 611 HTML (1 KB)  PDF  (694 KB)  ( 235 )

RUAN Jiu-gen,HU Jin-hua,FU Shui-ping,et al.

Objective:To analyze the applying value of MRI diffusion weighted imaging combination with dynamic enhanced scan in the diagnosis of hepatic space-occupying lesions.Method:49 patients with liver space-occupying lesions in our hospital were selected as the research objects from July 2010 to July 2014, the clinical data of patients were retrospectively analyzed.Result:All patients were successfully completed the examination cavernous,hemangioma had high apparent diffusion coefficient, followed by liver metastases, the lowest for primary hepatocellular carcinoma( HCC). Malignant liver tumors compared with hemangioma of ADC values,the difference was statistically significant(P<0.05). The dynamic enhancement curve of primary hepatocellular carcinoma( HCC) were mainly 10 cases(47.62%)of Ⅰ type,liver metastases were mainly 9 cases(60.0%) of Ⅱ type, hemangiomas were mainly 33 cases(67.35%) of Ⅲ type,and compared three kinds of liver placeholder dynamic contrast enhancement curve type ,the difference was statistically significant(P<0.05).The diagnostic accuracy of DWI combined with dynamic contrast-enhanced scan was higher than that of dynamic contrast-enhanced scan.Conclusion: MRI diffusion weighted imaging combination with dynamic enhanced scan in clinical diagnosis of liver space-occupying lesions can effectively improve the diagnostic accuracy rate,it is worthy of popularization and application.

2015 Vol. 12 (28): 118-121 [Abstract]( 699 HTML (1 KB)  PDF  (714 KB)  ( 197 )

DUAN Yong-hua,SONG Fang-qing,WANG Chun-mei,et al.

Objective:To explore the clinical effect of braces traction in children with jaw fracture.Method:The clinical data of 31 children with jaw fracture in our hospital from July 2012 to July 2014 were retrospectively analyzed.All patients were given the treatment of braces traction.Result:The total effective rate was 90.32%.The scores of plaque index,debris index and gingival index after treatment were higher than those before treatment,the differences were statistically significant(P<0.05).All patients had no infection and occlusal disorder.During the follow-up there were no patients with growth restriction and secondary deformity.Conclusion:Braces traction in children with jaw fracture can obtain good effect.

2015 Vol. 12 (28): 121-123 [Abstract]( 683 HTML (1 KB)  PDF  (692 KB)  ( 214 )

SUN Lian-ming.

Objective: To analyze and discuss the clinical effect of metal stents on the treatment of esophageal carcinoma stricture. Method: 36 patients diagnosed as esophageal carcinoma stricture from July 2010 to July 2013 were selected as the subjects for this study, and all of them were treated with endoscopic placement of covered metal stents. All the clinical materials from these patients were analyzed retrospectively, and the treatment method and effect were assessed. Result: All the 36 patients with esophageal carcinoma stricture had 100% success rate after treatment. The patients’ main clinical symptoms like difficulty in swallowing, irritating cough, vomiting after eating had been improved obviously. The grading-score of difficulty in feeding after 2 weeks had decreased from 3.26 before treatment to 1.03. The main complications after the endoscopic placement of covered metal stents were including pain, bleeding, esophageal restenosis, gastro-esophageal reflux and stent shifting, and the complications were reduced or disappeared through subsequent treatment. The follow-up visits showed that the patients’ survival time had been improved significantly. Moreover, the patients’ self-rating anxiety scale and self-rating depression scale before and after treatment had a significant difference( P<0.05). Conclusion: The treatment of esophageal carcinoma stricture through endoscopic placement of covered metal stents has significant treatment effect, simple procedure, high safety, small surgical trauma to patients and a high success rate that it’s worth for being widely used in the clinic.

2015 Vol. 12 (28): 124-127 [Abstract]( 573 HTML (1 KB)  PDF  (725 KB)  ( 273 )

LI Hai-jun,XU Guan-sheng,TAN Zhi-hua,et al.

Objective:To discuss the narrow band imaging combined with magnifying endoscopy(NBI-ME) apply in the clinic about chronic flat erosive gastritis. Method:186 patients with chronic flat erosive gastritis in our hospital who accord the diagnosis of endoscopic samples were selected from April 2013 to October 2014,they were randomly divided into three groups,ordinary endoscopy+biopsy group for 70 cases,NBI-ME+biopsy group for 62 cases and NBI-ME group for 54 cases, the atrophy and intestinal metaplasia of three groups were compared. Result:The diagnosis result of chronic plainness erosive gastritis with atrophy and intestinal metaplasia in NBI-ME group was better than endoscopy+biopsy group,the difference was statistically significant(P<0.05). Conclusion:The NBI combined with magnifying endoscopy in flat erosive gastritis at basic hospital has great significance.

2015 Vol. 12 (28): 127-129 [Abstract]( 608 HTML (1 KB)  PDF  (692 KB)  ( 313 )

LI Qiang,YU Shi-ping,SU Xiu-qin,et al.

Objective:To study the short-term effects of percutaneous transhepatic cholangio-drainage combining with biliary stent in different obstruction areas of malignant obstructive jaundice. Method:72 patients with malignant obstructive jaundice who accepted DSA-guided biliary stent at the department of interventional radiology in the Second Hospital of Shanxi Medical University were selected and reviewed from September 2010 to September 2014.According to the different obstruction area,they were divided into high obstruction group for 30 cases and low obstruction group for 42 cases, before and after operation, the situation of total bilirubin changes in two groups were compared.Result:All the patients successfully punctured and the success rate of puncture was 100%. Before and after operation,the changes of total bilirubin of two groups had statistically significant(P<0.05).The decrease in bilirubin of low obstruction group was more significantly than that of high obstruction group,the difference was statistically significant(P<0.05). Conclusion:Biliary stenting is an effective method for malignant obstructive jaundice of palliative treatment. Compared with high malignant obstructive jaundice, the short-term effect on low malignant obstructive jaundice is more satisfied.

2015 Vol. 12 (28): 130-133 [Abstract]( 534 HTML (1 KB)  PDF  (898 KB)  ( 212 )

CHEN Jian-ping, WU Hong-lin, GAO Yong-bing, et al.

Objective: To investigate the value of dual-energy CT angiography( CTA) in the diagnosis of intracranial aneurysms. Method: A retrospective analysis was studied about the clinical manifestations of 50 cases of intracranial aneurysms and dual-energy CTA signs, including the volume rendering( VRT), the maximum intensity projection( MIP). Result: 34 aneurysms were detected out of 50 patients, including 1 anterior cerebral artery aneurysm,9 anterior communicating artery aneurysms, 10 posterior communicating artery aneurysms, 4 intracranial internal carotid artery aneurysms, 9 middle cerebral artery aneurysms, and 9 basilar artery aneurysms. The maximum diameter of the aneurysm was 15 mm. DSA detected 35 ones, and CTA missed an anterior communicating artery aneurysm. Conclusion: Dual energy CTA is a safe, non-invasive, fast imaging method, which can be used as the preferred screening method.

2015 Vol. 12 (28): 133-135 [Abstract]( 572 HTML (1 KB)  PDF  (861 KB)  ( 278 )

PIAO Shu-hua,FENG Wen-xiao,LI Yan-xia.

Objective:To explore the value of hysteroscopy in diagnosis of endometrial neoplasia.Method:85 cases who underwent hysteroscopic examination and diagnostic curettage were analysed retrospectively. of the clinical manifestations, preoperative ultrasound characteristics, surgical methods and the consistency results of the pathological diagnosis of the patients were analysed.Result: 64 patients underwent hysteroscopy examination,37 patients of reproductive period with preoperative ultrasound tip intrauterine placeholder growth, 27 menopausal women of preoperative ultrasound tip intrauterine placeholder were 9 cases and 18 cases of endometrial thickening.Endometrial polyp detection rate of 37 cases with hysteroscopy examination in the reproductive period was 72.97%,which was significantly higher than 9.52% of the diagnostic curettage examination.But the detection rate of uterine endometrial cancer, uterine endometrial atypical hyperplasia, simple endometrial hyperplasia, and proliferative endometrial in diagnostic curettage check were higher than hysteroscopy examination. In menopausal women,preoperative ultrasound prompted the placeholder of 9 cases, hysteroscopy check 100% had intrauterine implement qualitative sex pathological change; preoperative ultrasound prompted 18 cases of endometrial thickening,hysteroscopy examination revealed 8 cases( 44.44%) normal endometrium,10 cases of endometrial lesions, including 2 cases( 11.11%) of endometrial malignant lesions,8 cases(44.44%)of endometrial polyps.Conclusion: Hysteroscopy has important value in the diagnosis of intrauterine lesions,but it is necessary to apply the technique of hysteroscopy in the diagnosis of different endometrial lesions diseases,reduce unnecessary invasive examination and treatment.

2015 Vol. 12 (28): 136-139 [Abstract]( 673 HTML (1 KB)  PDF  (710 KB)  ( 370 )

YUAN Yu-huan,MAI Hui-qiong,LIU Er-ying,et al.

Objective:To observe and compare the clinical effect of compound Danshen injection and 50% Magnesium sulfate solution wet packing in treatment of neonatal transfusion exosmose. Method:131 newborn with intravenous infusion in our hospital were chosen from September 2011 to July 2014.All patients had symptoms of infusion extravasation and were randomly divided into the control group of 65 cases and the observation group of 66 cases.The control group was given 50% magnesium sulfate wet solution treatment,while the observation group was treated by compound Danshen injection.The swelling time, onset time, the therapeutic effect and adverse reaction of two groups were compared. Result:The start swelling time,the complete detumescence time and the effective time of observation group were respectively( 2.78±0.57)h,(9.12±1.13)h and( 5.73±0.63)h,while those time in the control group were respectively( 5.61±1.49)h,(16.32±1.43)h and( 10.54±1.05)h,the observation group were shorter than those of the control group ,the differences were statistically significance(P<0.05).The total effective rate of the observation group and the control group were respectively 98.48% and 73.85%,the observation group was higher than that of control group,the difference was statistically significance(P<0.05).The observation group had no obvious adverse reaction,while the occurrence of adverse reactions in the control group was 12.31%,the observation group was significantly better than the control group ,the difference was statistically significance(P<0.05).Conclusion:Neonatal transfusion exosmosis with compound Danshen injection has fast acting,good effect and high safety,it is worth popularization.

2015 Vol. 12 (28): 139-142 [Abstract]( 540 HTML (1 KB)  PDF  (713 KB)  ( 293 )

GU Yi-bo, LIU Ping, DU Hai-yan,et al.

Ovarian cancer is a serious threat to the life and health of women’s higher fatality rate of gynecologic malignant tumors. Only deep and study the mechanism of development can explore the new areas for its diagnosis and treatment so as to improve the overall survival of patients. Related factors and the findings of a study of ovarian cancer is relatively more, including survivin factor is current research hotspot. Through review the structure characteristics and mechanism role of survivin, summarizing its development with the incidence of ovarian cancer, angiogenesis, prognosis,correlation between chemotherapy drug resistance and so on, is expected to help the study and treatment of ovarian cancer.

2015 Vol. 12 (28): 149-152 [Abstract]( 443 HTML (1 KB)  PDF  (725 KB)  ( 255 )

OU Yan-mian.

The homocysteine( HCY) is a kind of intermediary metabolism substance produced by methionine demethylation, and HCY is called high homocysteine( HHCY) when its level is higher than that at 10 μmol/L. H-type hypertension refers to primary hypertension that plasma HCY level exceeded 10 μmol/L. Chinese people’s living standard significantly improved in recent years,, great changes in diet structure and social impact on the environment drove sharp rise in the morbidity of H-type hypertension, and showed continuous increase. H-type hypertension might induce numerous cardiovascnlar and cerebrovascular diseases, and it was the main reason of cerebral apoplexy. In view of the reality that the incidence of H-type hypertension increased year by year, effective targeted prevention scheme and early detection on such disease can effectively control the incidence of cardiovascular disease and stroke in China and improve overall level of population health, and the implementation on H hypertension research delivers important realistic meaning and medical significance. Domestic and foreign scholars continuously deepen researches on H-type hypertension in recent years, and a large number of new literatures appeared constantly, providing more reference information for the prevention and control over H-type hypertension. This definition, harmfulness, pathogenesis, treatment and prevention of summarized research progress on H-type hypertension in recent years are summarized in this paper for purpose of providing the reference for the prevention and treatment of H-type hypertension in the future.

2015 Vol. 12 (28): 153-156 [Abstract]( 783 HTML (1 KB)  PDF  (712 KB)  ( 406 )

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