Objective：To explore the clinical efficacy of locking proximal femur plates and PFNA treated with unstable intertrochanteric fractures.Method：106 patients with unstable intertrochanteric fractures were randomly divided into the PFNA group and the locking proximal femur plates group（LPFP），each group contained 53 cases.The PFNA group were given the new system for the treatment of unstable intertrochanteric fractures and the LPFP group were treated with locking proximal femur plates.The surgery-related indicators，the Harris hip scores of 3months and 12 months after surgery and the complications were compared.Result：The mean operative time，postoperative bed braking time and fracture healing time of the PFNA group were significantly lower than that of the LPFP group（P<0.001）.The efficacy and excellent rate in the PFNA group after 3 months and 12 months of followed-up were significantly higher than that in the LPFP group（P<0.05）.Severe orthopedic complications such as the head and neck shortened，femoral neck cut，varus，plant failure and femoral shaft fractures didn’t appear in PFNA group.5 patients’ proximal femoral locking plate fractured and caused varus deformity.The difference in orthopedic complications of the two groups of patients were significantly different（ χ²=5.248，P=0.022）.Conclusion：Compared with LPFP surgery，PFNA treatment has the advantages of shorter operative time，shorter postoperative bed short braking time，quick recovery after surgery，good recovery of hip function and fewer complications，so it is worth applications.

2015 Vol. 12　(16):　4-7 [Abstract]（ 474 ） HTML (1 KB)  PDF  (695 KB)  ( 197 )

Objective：To study expression and significance of CK5/6，CK8/18，SMA，P63，ER in introductal proliferative lesions（ IDPL） of the breast.Method：A total of 150 breast IDPL specimens collected from the Department of Pathology of Xiaogan Central Hospital between 2003 and 2013 were tested，including usual ductal hyperplasia（ UDH） in 21，flat epithelial atypia（ FEA） in 46，atypical ductal hyperplasia（ ADH） in 51，and ductal carcinoma in situ（ DCIS） in 32（ all low-garde）.The expression of CK5/6，CK8/18，SMA，P63，ER were detected by immunohistochemical EnVision method.Result：The positive expression of CK5/6 in UDH group was significantly higher than that in ADH group，DCIS group and FEA group（ P<0.05）.That in ADH group was higher than that in DCIS group and FEA group（ P<0.05）.The differences were not significant between DCIS group and FEA group.The expression of CK8/18 in all cases showed no positive expression in basal and showed positive expression in luminal that in UDH group，FEA group，ADH group，DCIS group was not significantly different. The positive expression of SMA and P63 was Continuous in basal.That in UDH group，FEA group，ADH group，DCIS group was not significantly different.There were not positive expression in luminal in FEA group，ADH group and DCIS group，only showed a few scattered positive expression in UDH group（ positive cell <5%）.The expression of ER in UDH group compared with in FEA group，ADH group and DCIS group，there was significantly different（ P<0.05）.That in FEA group，ADH group，DCIS group was not significantly different.Conclusion：The combined detection of CK5/6，CK8/18，SMA，P63，ER is helpful to pathological diagnosis and differential diagnosis of breast proliferative lesions.

2015 Vol. 12　(16):　10-12 [Abstract]（ 863 ） HTML (1 KB)  PDF  (671 KB)  ( 329 )

Objective：To study the influence of clinical pharmacist intervention model on compliance，clinical efficacy and life quality of warfarin.Method：60 patients with chronic AF were selected in our hospital from June 2013 to June 2014 as the research object，and were divided into observation group and control group according to the discharge order，30 cases in each group.The observation group was treated with clinical pharmacist intervention，control group was treated without pharmacists，drug compliance，efficacy and life quality of two groups were compared. Result：The total compliance of the observation group was 86.67%，significantly higher than the control group of 63.33%，the difference was statistically significant（P<0.05）；occurrence rates of thrombosis and bleeding rates of observation group were 0 and 6.67%，significantly lower than control group of 13.33% and 26.67%，the differences were statistical significance（P<0.05）； when the observation group discharged after 1 years，the scores were significantly higher than those in the control group，the differences were statistically significant（P<0.05）.Conclusion：Pharmacists intervention mode to accept warfarin treatment can improve the medication compliance and curative effect，improve the quality of life of patients，has high clinical value.

2015 Vol. 12　(16):　16-18 [Abstract]（ 544 ） HTML (1 KB)  PDF  (670 KB)  ( 278 )

Objective：To summarize the application effect of rapid rehabilitation application concept in traumatic splenic rupture patients in the anesthetic management in peri operation period.Method：From January 2010 to October 2014，in the Xinjiang Nongyishi hospital Alar people admitted the Department of general surgery，100 cases of traumatic rupture of spleen operation，according to the method of random number table were divided into two groups，the patients were informed consent，50 patients in the control group were administered conventional peri operation period nursing，50 cases of the observation group were given the concept of rapid rehabilitation applied to fluid management of peri operation period，index of anesthesia，gastrointestinal function recovery time，mean length of hospital stay，cost of hospitalization and postoperative complication rate of patients in the two groups were compared.Result：The recovery time，pull the groups of patients with tube time of the observation group were significantly lower than the control group patients，there were significant differences（ P<0.05）.In comparison to CRP level，after 1 day and 5 days after operation，the observation group were significantly lower than those in the control group，there were significant differences between the（ P<0.05）.The gastrointestinal function recovery time，mean length of hospital stay，hospital costs of patients in the observation group were lower than the patients in the control group，there were significant differences between the two groups.2 patients in the observation group had complications，　which was significantly lower than the patients of the control group，there was significant difference（ χ²=4.382，P<0.05）.Conclusion：The application effect of rapid rehabilitation application concept in traumatic splenic rupture patients in the anesthetic management in peri operation period issatisfactory，it can accelerate the process of rehabilitation of patients.

2015 Vol. 12　(16):　22-24 [Abstract]（ 601 ） HTML (1 KB)  PDF  (670 KB)  ( 237 )

Objective：To explore the value of routine examination in each healthy of the detection of malignant tumors. Method：95 267 cases of healthy information in our hospital from 2011 to 2012 were retrospectively analyzed， and 179 cases of cancer diagnosed by histopathology were grouped by tumor category， inspection methods to compare detection rate and constituent ratio.Result：Ultrasound detected up to 110 cases， followed by 37 cases of radiation in the 179 cases of cancer diagnosed by histopathology.The total positive rate of malignant tumor was 1.879 per thousand.Ultrasound showed the highest detection rate was 1.155 per thousand， followed by radiation 0.388%.Conclusion：Cancer screening has become one of the important objective of health examination， and ultrasound has obvious advantages in the detection of malignant tumor.It was followed by radiation.

2015 Vol. 12　(16):　28-30 [Abstract]（ 405 ） HTML (1 KB)  PDF  (671 KB)  ( 219 )

Objective：To study and analyze the impacts of different anesthesia methods on the circulatory function of elderly patients during lower limb fracture surgery.Method：90 patients with lower limb fracture admitted in our hospital from September 2012 to May 2013 were retrospectively analyzed.They were divided into general anesthesia group and CSEA group and given general anesthesia， CSEA， separately.MAP， HR， RR and SPO2 at T0（ before anesthesia）， T1（ after anesthesia）， T2 （operation was performed for 5 min）， T3（ operation was performed for 15 min）， T4（ operation was performed for 30 min） and T5（ operation was performed for 60 min） of the two groups were compared.Result：In general anesthesia group， the change of MAP was（ 108.1±8.8）mm Hg，（ 88.3±4.2） mm Hg and in CSEA group was（ 107.9±9.2） mm Hg，（ 103.5±3.7） mm Hg，the change in the former was more than that in the latter， the difference was statistically significant（ P<0.05）.In general anesthesia group， the change of HR was（ 85.2±4.6）times/min，（65.8±5.3） times/min and in CSEA group was（ 87.6±3.2） times/min，（73.3±4.6） times/min， the changes in the former were much more than those in the latter， the difference was statistically significant （P<0.05）.The differences in SpO2 and RR between groups were not statistically significant（ P>0.05）.Conclusion：CSEA for lower limb fracture surgery of elderly patients has little change in each index during the operation； it has good anesthetic effect with little impact on the circulatory function of patients， so it’s more suitable to be applied in lower limb fracture surgery of elderly patients with higher safety.

2015 Vol. 12　(16):　33-35 [Abstract]（ 427 ） HTML (1 KB)  PDF  (672 KB)  ( 172 )

Objective：To discuss the recovery of function and voice training time after microsurgical operation of vocal cords.Method：152 vocal cord polyps patients with vocal cord microsurgery from January 2011 to April 2014 in institute of otolaryngology department as research objects，using the voice acoustic analysis，compared to the voice acoustic parametersduring preoperative and postoperative 3，5，7 days.In accordance with the draw random sampling method 152 patients were divided into two groups，patients in group A at 1 weeks after surgery to give voice training，patients in group B at 2 weeks after surgery to give voice training.6 months after voice training，to compare the voice acoustic parameters，VHI scores and GRBAS scores of the two groups.Result：3 d after the operation，the acoustic parameters in patients decreased，had no significant difference compared with that before operation，from 5 d after operation，the acoustic parameters significantly decreased compared with that before operation，there were differences in statistical significance（ P<0.05）.Before voice training，two groups of patients with voice acoustic parameters，VHI scores and GRBAS scores had no significance，6 months after voice training，two groups of patients with voice acoustic parameters，VHI scores and GRBAS scores were significantly improved，group B improved more significantly than group A（ P<0.05）.Conclusion：The voice quality begin to restore 5 d after surgery in patients with vocal cord polyp microstructure，but patients within 2 weeks after a rigorous hugh rear can make voice training.

2015 Vol. 12　(16):　39-41 [Abstract]（ 581 ） HTML (1 KB)  PDF  (671 KB)  ( 203 )

Objective：To investigate the clinical efficacy and safety of biotype total hip replacement for patients with femoral head necrosis and femoral neck fracture.Method：Cases with femoral head necrosis and femoral neck fracture in our hospital 2010 February to 2012 February were divided into two groups according to the random number table method，treatment group underwent biotype total hip replacement，control group underwent artificial femoral head replacement，compared with the clinical efficacy and safety of two groups.Result：Operation time，intra-operative bleeding volume of treatment group were larger than those of control group，postoperative drainage，hospitalization time less than those of control group，the difference was statistically significant（ P<0.05）.The two group patients were followed up for 16-24 months（ 20.7±2.5） months，the Harris score of treatment group was superior to that of control group，the difference had statistical significance（ P<0.05），postoperative complications of the two groups included wound fat liquefaction，deep vein thrombosis，prosthesis dislocation，infection，pulmonary infection.The incidence of prosthesis dislocation and wound infection was lower than that of control group，the difference was statistically significant（ P<0.05），there was no significant difference in other complications after operation between two groups. Conclusion：Biotype total hip replacement in treatment of patients with femoral head necrosis and femoral neck fracture has a characteristic of good long-term curative effect，high safety，quickly functional recovery，and it has important reference value.

2015 Vol. 12　(16):　44-47 [Abstract]（ 480 ） HTML (1 KB)  PDF  (694 KB)  ( 383 )

Objective：To investigate the value of rosuvastatin，atorvastatin combined with regular exercise therapeutic for coronary heart disease.Method：180 patients with coronary heart disease were selected，and randomly divided into rosuvastatin group and atorvastatin group，90 cases in each group，the rosuvastatin group was given rosuvastatin for treatment，and the atorvastatin group was given atorvastatin for treatment，two groups were combined with regular exercise，the total efficiency，blood pressure，lipid levels，baPWV levels and incidence of adverse reactions before and after treatment were compared.Result：The total effective rate of rosuvastatin group was 96.7%，and that of the atorvastatin group was 87.8%，the difference was statistically significant（ P<0.05）.Lipid levels between the two groups before treatment had no significant changes，TC，TG，LDL-C of the rosuvastatin group was significant lower than that of the atorvastatin group after treatment，and HDL-C was significant higher than that of the atorvastatin group after treatment（ P<0.01）.baPWV levels between the two groups before treatment had no significant difference，baPWV levels of the rosuvastatin group after treatment was significantly lower than that of the atorvastatin group（ P<0.01）.Adverse reactions of the rosuvastatin group after treatment was 17.8%，and that of the atorvastatin group was 31.1%，the difference was significant（ P<0.05）.Conclusion：The effect of　rosuvastatin combined with regular exercise treatment of coronary heart disease is significant，and can significantly reduce the incidence of cardiovascular events，improve arterial stiffness in patients.

2015 Vol. 12　(16):　49-51 [Abstract]（ 551 ） HTML (1 KB)  PDF  (673 KB)  ( 161 )

Objective：To investigate the curative effect of polycystic ovary syndrome patients with comprehensive use of insulin sensitizing agent endocrine disorders. Method：In our hospital in 2012 August to 2013 November 56 polycystic ovary syndrome patients were selected as the research objects，and randomly divided into 28 cases in control group and 28 cases in observation group，the control group accpeted citric clomiphene citrate，Marvelon，Xu acid Estradiol Tablets combined treatment，the observation group based on the control group accepted insulin sensitizing sensitive agent treatment，the two groups were analyzed after treatment.Result：In the observation group the total effective rate was 92.86%，71.43% in the control group，the difference was statistically significant（ P<0.05）.In all the time，insulin levels of the observation group were lower than those of the control group（ P<0.05）. Conclusion：Based on conventional treatment scheme on the use of insulin sensitizing agent for the treatment of polycystic ovary syndrome，endocrine disorders in patients with significant effect，high safety，is worth to be popularized in clinical use.

2015 Vol. 12　(16):　54-56 [Abstract]（ 543 ） HTML (1 KB)  PDF  (672 KB)  ( 319 )

Objective：To study the effect of hormone replacement therapy on blood FSH and E2 levels of perimenopausal syndrome women and explore the clinical applicability.Method：76 perimenopausal syndrome cases were selected and divided into two groups，38 cases in each group.The observation group was treated with hormone replacement therapy，the control group was treated with oryzanol tablets，the blood FSH and E2 levels and the clinical effect were compared.Result：The changes of blood FSH and E2 levels of the control group were not obvious，the difference was not statistically significant（P>0.05）.The blood E2 level after therapy（48.37±17.01）pg/mL was higher than before（28.53±18.55）pg/mL，the blood FSH level after therapy（13.01±10.74）IU/L was lower than before（31.02±16.57）IU/L in the observation group，the difference was statistically significant（P<0.05）.  Clinical effective rate was 86.84% in the observation group and 63.16% in the control group，the difference was statistically significant（P<0.05）.Conclusion：Hormone replacement therapy used in perimenopausal syndrome women can decrease FSH level，increase E2 level and improve the clinical effect，it is suitable for clinical application.

2015 Vol. 12　(16):　59-62 [Abstract]（ 625 ） HTML (1 KB)  PDF  (695 KB)  ( 212 )

Objective：To study the clinical effect of adding Tong Xinluo on the basis of metoprolol for the coronary heart disease with heart failure.Method：96 patients who were admitted in our hospital in recent years for coronary heart disease with heart failure were selected.They were radomly divided into the observation group and the contrast group at random.The contrast group was treated with metoprolol alone.The observation group was added Tong Xinluo on the basic treatment of the contrast group.The promotion of cardiac function and the control effect of the clinical symptoms between the two groups were compared.Result：Two groups had no obvious differences on cardiac function before the treatment.But the cardiac function of the the observation group improved more obviously after the treatment（ P<0.05）.On the treatment effect，the efficient rate of the contrast group was 81.25%，but the observation group can achieve 95.83%.There was significant difference between the two groups（ P<0.05）.Conclusion：Coronary heart disease with heart failure patients can get better clinical efficacy when they use Tong Xinluo capsule on the basis of the conventional therapy.Their cardiac function improved ulteriorly.This method has promotion value.

2015 Vol. 12　(16):　65-67 [Abstract]（ 452 ） HTML (1 KB)  PDF  (673 KB)  ( 158 )

Objective：To investigate the effect of the application of Tirofiban in treatment of the acute myocardial infarction（ AMI），and to accumulate experience for the clinical treatment of the disease.Method：89 patients who were in accordance with the inclusion criteria of AMI were randomly divided into control group（ 43 cases） and observation group（ 46 cases）.The patients in the two groups were given oral clopidogrel and aspirin tablets and the subcutaneous injection of lowmolecular- weight heparin.Based on the treatment above，the control group used micro-injection pump to continuously pump heparin into the patients at the speed of 1000 U/hour which lasted 36 hours，while the observation group used micro-injection pump to continuously pump Tirofiban into the patients at the speed of 0.15 μg/（kg·min） which lasted 36 hours.The changes in electrocardiogram，the incidence of major adverse cardiac events and the occurrence of adverse reactions of the patients between the two groups were compared.Result：Before the medicine was given，the differences of the ST segment depression and ischemia lead number of the patients between the two groups had no statistical significance（ P>0.05），but after the medicine was given，the ST segment depression and ischemia lead number of the patients in the two groups improved a lot（ P<0.05）.The improvement of the observation group was much better than that of the control group（ P< 0.05）.The incidence of major adverse cardiac events of the observation group was significantly lower than that of the control group（ P<0.05）.The incidence of adverse reactions of the observation group was higher than that of the control group，but the difference was not statistically significant（ χ² =0.412，P>0.05）.Conclusion：Tirofiban can effectively regulate the changes in electrocardiogram of patients with AMI and reduce the incidence of major adverse cardiac events.Tirofiban is safe，which is worth clinical application.

2015 Vol. 12　(16):　70-72 [Abstract]（ 524 ） HTML (1 KB)  PDF  (672 KB)  ( 223 )

Objective：To investigate the clinical effects of early enteral nutrition support for the immune function of patients with severe stroke.Method：110 patients with severe stroke in our hospital were randomly divided into research group and control group，each contained 55 cases.The research group was treated with early enteral nutrition support therapy.The control group was treated with parenteral nutrition support therapy.The hemoglobin（ Hb），serum albumin（ Alb），triglyceride（ TG），T lymphocyte subsets（ CD3+，CD4+，CD8+） before and after treatment and complication rate was compared.Result：After 3 weeks of treatment，the Hb，Alb，TG of the research group was higher than that of the control group，the CD3+，CD4+ was higher than that of the control group，the CD8+ of research group was lower than that of the control group（ P<0.05）.The complication rate of the research group was 10.9%，which was lower than 32.7% of the control group（ P<0.05）.Conclusion：Early enteral nutrition support for the immune function of patients with severe stroke has exact effect.It can effectively improve nutritional status，enhance immunity and reduce complications.It’s worthy of clinical widely used.

2015 Vol. 12　(16):　75-78 [Abstract]（ 529 ） HTML (1 KB)  PDF  (694 KB)  ( 168 )

Objective：To contrast and analysis the curative effect of treatment on pelvic fracture and acetabular fracture by Modified Stoppa approach and ilioinguinal approach.Method：65 cases with pelvic fracture and acetabular fracture in our hospital from January 2010 to December 2014 were divide into two groups，Modified Stoppa approach group 40 cases and ilioinguinal approach group 25 cases.Their clinical date was analyzed.Result：The operation time，intraoperative blood loss and length of incision of Modified Stoppa approach group were lower than that of the ilioinguinal approach group.The reset quality of Modified Stoppa approach group was higher than the ilioinguinal approach group.The good rate of the hip joint function of the Modified Stoppa approach group was higher than that of the ilioinguinal approach group.The differences were statistically significant（ P<0.05）. Conclusion：The curative effect of treatment on pelvic fracture and acetabular fracture by Modified Stoppa approach are obviously.This method is worth clinical spreading.

2015 Vol. 12　(16):　81-83 [Abstract]（ 484 ） HTML (1 KB)  PDF  (673 KB)  ( 356 )

Objective：To analyze the application and clinical effects of remifentanil with sevoflurane in the controlling hypotension for nasal endoscopic surgery.Method：84 patients who were conducted the nasal endoscopic surgery in our hospital from March 2012 to June 2014 were taken as the research objects，and these patients were randomly divided into control group and observation group，with 42 patients in each group.Then，both of the two groups were adopted the sevoflurane combined intravenous with inhalation anesthesia.Then，in the control group，they were treated with the nitroglycerin while in the observation group，they were treated with the remifentanil.Then，the change of HR in the different periods during the operations and the situations after surgeries of both the two groups were observed.Result：The HR during the hypertension in the observation group was evidently lower than the control group.In addition，the SSFQ score and the intraaoperative blood volume in the observation group were evidently lower than that in the control group and the differences had the statistical significance（ P<0.05）. However，the extubation time did not have evident significances（ P>0.05）.Conclusion：The applications of remifentanil with sevoflurane in the controlling hypotension for nasal endoscopic surgery can effectively improve the bradycardiac，promote the steady blood pressure and decrease the blood volume during the surgeries.Thus，it should be promoted in the clinic applications.

2015 Vol. 12　(16):　86-88 [Abstract]（ 419 ） HTML (1 KB)  PDF  (671 KB)  ( 192 )

Objective：To explore the effect of community nurses to carry out the analysis of postpartum visit nursing on puerperal women and newborns and relative value.Method：240 cases of maternal in our hospital from October 2013 to October 2014 were treated as the research object，and were divided into the observation group and the control group by the method of random number，120 cases in each group.The observation group parturients with postpartum visit，while the control group did not use the maternal postpartum visit.Result：Two groups of mothers through clinical care，the observation group maternal awareness rate was 92.5%，while the control group awareness rate was 75.0%，the rate was significantly better than the control group，the difference has statistical significance（P<0.05）.Conclusion：Postpartum visit nursing application in neonatal and puerperal women，it has good clinical effect，and it is beneficial to improve maternal neonatal care and rehabilitation of self awareness of knowledge，it is worth in clinical application.

2015 Vol. 12　(16):　92-93 [Abstract]（ 409 ） HTML (1 KB)  PDF  (649 KB)  ( 306 )

Objective：To study the effect of bundle interventions on prevention of the ventilator-associated pneumonia （VAP） in primary hospital so as to provide reference.Method：A total of 91 patients who underwent mechanical ventilation for more than 48 hours from 2012 to 2013 were enrolled in the study and divided into two groups.43 patients were subjected into the interventions group，and 48 patients were subjected into the control group，the bundle interventions were adopted，and the incidence of VAP was compared between the two groups.Result：The bundle interventions could effectively prevent the incidence of VAP.After the implementation of bundle interventions，there were 10 cases with VAP in the intervention group with the incidence of 17.48 ‰ and 23 cases in the control group with the incidence of 40.00 ‰ .The infect rate of the patients using breathing machine last 48 hours decreased from 47.92 ‰ to 23.26 ‰ .The bundle intervention compliance directly affected the consequence.Conclusion：Cluster intervention measures of fully implement can effectively reduce the occurrence of VAP in ICU，its compliance is directly affect the outcome.Measures implementation is the core of its intervention effect，take corresponding measures to improve the clinical medical staff compliance of intervention measures，is the feeling of department to reduce VAP have been the focus of the management by objectives.

2015 Vol. 12　(16):　97-99 [Abstract]（ 536 ） HTML (1 KB)  PDF  (695 KB)  ( 245 )

Objective：To explore the application method and effect of the full range of nursing intervention for the patients with misoprostol used before curettage. Method：240 patients with misoprostol used before curettage in our stand from July 2012 to September 2014 were selected and，divided into the observation group and the control group，120 cases in each group.The control group was given routine nursing care and the observation group was given a full range of nursing intervention measures. The nursing effect of the two groups was compared.Result：In the observation group，on the aspect of cervix softening，97 cases were excellent，accounting for 80.83%，17 cases were effective，accounting for 14.16%，6 cases were ineffective，accounting for 5.01%，the total effective patients were 114，accounting for 94.99%.The average operation time was（ 7.89±1.22）min. The average amount of bleeding was（ 10.15±6.33）mL.34 cases appeared misoprostol side reaction，all of whom successfully overcame in surgery.Patients’ satisfaction with the full range of nursing was 100%.While in the control group，on the aspect of cervix softening，83 cases were excellent，accounting for 69.17%，12 cases were effective，accounting for 10%，25 cases were ineffective，accounting for 20.83%.the total effective rate was 79.17%.The average operation time was（ 13.13±2.18）min.The average amount of bleeding was（ 29.36±10.78）mL.30 cases appeared misoprostol side reaction 12 cases successfully overcame the adverse drug reaction，accounting for 40% of the total.Patients’ satisfaction with nursing care was 59.17%.Conclusion：The effect of the full range of nursing intervention on patients with misoprostol before curettage is significant.It can be widely used in clinical practice.

2015 Vol. 12　(16):　103-106 [Abstract]（ 466 ） HTML (1 KB)  PDF  (692 KB)  ( 164 )

Objective：To study the influence of complementary feeding baby reasonable care and education for the incidence of iron deficiency anemia produced.Method：300 infants aged 4-12 months were selected in the hospital from May 2013 to May 2014，all infants were carried out before adding complementary determination of trace elements，and were divided into two groups，150 cases in each group.Infants in the control group did not care to add complementary missions，infants in the observation group were given nursing education complementary feeding before implementation，the incidence of iron deficiency anemia of complementary feeding after 3-6 months infants were compared.Result：Compared two groups of infants，the control group of children before adding complementary and add content in whole blood from 3 to 6 months after the Fe trace elements in food supplement significantly reduced，while the observation group of children before adding complementary and complementary feeding after 3 to 6 months significantly increased trace element content of Fe，which showed reasonable complementary clinical effects of significant public education，had effectively enhance Fe content of trace elements in whole blood of children.The observation group infants with iron deficiency chance of anemia was 12.0% significantly lower than the control group of 30.0%，in the observation group was the control group，the difference was statistically significant（P<0.05）.Conclusion：The need for parents to implement complementary feeding baby nursing education can effectively reduce the incidence of iron deficiency anemia，and promote the healthy development of infants and should be introduced in clinical practice.

2015 Vol. 12　(16):　109-112 [Abstract]（ 530 ） HTML (1 KB)  PDF  (693 KB)  ( 281 )

　Objective：To explore the nursing measures of craniocerebral injury combined with risk accidents in clinical treatment of patients with compound injury.Method：78 patients of traumatic brain injury with complex trauma were selected and divided into the study group and the control group，39 cases in each group.The risk of traumatic brain injury with clinical care of patients with complex injuries were assessed，the study group was given a comprehensive care measures based on the assessment results，the control group was given routine care.Result：Before nursing，two groups of patients with HAMD score and ADL score had no significant difference（P>0.05）.After nursing，study group’s ADL scores were significantly higher than those of control group，HAMD score was significantly lower than that of the control group，the differences were statistically significant（P<0.05）. The study group clinical treatment of risk in the process of the accident rate was 15.4%，significantly lower than the control group of 38.4%，the satisfaction of nursing in study group was 92.3%，significantly higher than the control group of 74.4%，the differences were statistically significant（P<0.05）. Conclusion：The comprehensive nursing of craniocerebral injury combined with multiple trauma patients，can effectively reduce the incidence rate of clinical risk accidents，improve the clinical treatment
effect.

2015 Vol. 12　(16):　114-117 [Abstract]（ 571 ） HTML (1 KB)  PDF  (693 KB)  ( 173 )

Objective：To investigate the anti-proliferation effect of a series new phosphorylated chrysin derivatives in leukemia cells.Method：The cell viability of the 12 phosphorylated chrysin derivatives in Kasumi-1 cells was detected by MTT assay，and the derivatives with higher proliferation inhibition rate than chrysin were selected out to process the next step to verify the anti-proliferation effect in K562 cells，HL60 cells，U937 cells，and bone marrow mononuclear cells（ BMMNC） from acute leukemia patients.Result：Chrysin derivatives 3c and 7a could inhibit the proliferation of leukemia cells in vitro.Conclusion：The new phosphorylated chrysin derivatives 3c and 7a have potential value in anti-leukemia research.

2015 Vol. 12　(16):　120-123 [Abstract]（ 444 ） HTML (1 KB)  PDF  (804 KB)  ( 277 )

Objective：To observe the effect of preterm twins premature rupture of the clinical features and outcome of pregnancy.Method：40 cases of preterm twins in patients with premature rupture of membranes were selected as the treatment group，40 cases of preterm singleton in premature rupture of membrane as the control group，the two groups of patients with premature rupture of membranes，occurrence time，complication rate and neonatal prognosis were compared and analyzed. Result：In the treatment group，patients with anemia syndrome，fetal growth restriction，postpartum hemorrhage，premature rupture of fetal membranes，premature rupture of membranes before break time contractions rate，rupture of membranes to the time of termination of pregnancy，termination of pregnancy gestational age，fetal lung maturation time ≥ 48 h，use of tocolytic rate，premature delivery rate，cesarean delivery，neonatal weight，neonatal asphyxia and neonatal respiratory distress syndrome compared with control group，the difference was statistically significant（P<0.05）.Conclusion：The twins as the main factors leading to the premature rupture of membranes appear patients，clinical treatment more difficult，higher rate of preterm delivery and neonatal prognosis difficult，through scientific measures to prevent effective preterm twins premature rupture of membranes.

2015 Vol. 12　(16):　126-128 [Abstract]（ 547 ） HTML (1 KB)  PDF  (670 KB)  ( 209 )

Objective：To discuss the different types of lipoma ultrasonographic features，provide certain reference to clinical diagnosis of lipoma.Method：120 patients in our hospital lipoma，to use Phlips HD 11，LOGIQ 400 CL color doppler ultrasonic diagnostic instrument，7-12 MHz probe frequency，was set to the superficial small organ.Result：The ultrasonic diagnosis of lipoma，qualitative analysis，was helpful to the diagnosis and 120 patients in 98 cases（ 81.67%） were confirmed. Conclusion：Different types of lipoma ultrasonic testing showed that characteristics vary，typical lipoma is relatively easy to diagnose，fibrous tissue can be detected，ultrasound is helpful to diagnosis，is worth popularizing in clinical application.

2015 Vol. 12　(16):　131-133 [Abstract]（ 612 ） HTML (1 KB)  PDF  (671 KB)  ( 260 )

Objective：To explore the clinical effect of chest laparoscopic combined operation in the treatment of esophageal cancer.Method：30 cases of esophageal cancer patients were selected as research subjects from July 2011 to November 2014，according to the different methods of treatment，were divided into experimental and control groups，15 cases in each group.The control group was taken traditional thoracotomy，the experimental group was taken the chest laparoscopic combined operation，the surgery situation and postoperative complications of two groups were observed.Result：All patients were successfully completed surgery，compared to the situation in the experimental group were significantly better than the control group，the difference was statistically significant（P<0.01）； overall complication rate after two groups of patients，the experimental group was significantly lower than the control group，the difference was statistically significant（P<0.05）. Conclusion：Chest laparoscopic combined operation in the treatment of esophageal cancer has a good effect，the less blood loss，shorter hospital stay，less postoperative drainage，lymph node dissection，more thorough，and fewer complications，higher
safe，it is worth clinical application and promotion.

2015 Vol. 12　(16):　136-138 [Abstract]（ 460 ） HTML (1 KB)  PDF  (673 KB)  ( 289 )

Objective：To discuss the endometrial cancer treatment effects and prognosis investigate the incidence of complications.Method：From August 2005 to July 2013 in our hospital，166 patients of endometrial carcinoma with a variety of complications were selected as the comorbidity group，clinical data with the same period of 171 patients with uncomplicated endometrial cancer were selected as the control group，then they were compared and retrospectively analyzed. Result：Endometrial cancer of common complication were obesity of 132 cases，hypertension of 107 cases，and diabetes of 57 cases ；comorbidity group and the control group compared with surgery，extent of surgery patients，postoperative tumor staging and histological type，the differences were not statistically significant（P<0.05）.Comorbidity group was significantly older than the control group，the number of patients to receive chemotherapy higher than the control group，comorbidity group has a significant effect on the prognosis，the difference was statistically significant（P<0.05）. Conclusion：Patients with endometrial cancer are often associated with obesity，hypertension and diabetes，with age increases，the incidence of complications increased，comorbidities is a certain impact on the treatment of endometrial cancer，has a significant effect on the prognosis.

2015 Vol. 12　(16):　141-143 [Abstract]（ 413 ） HTML (1 KB)  PDF  (671 KB)  ( 186 )

Objective：To explore phosphatase in combination with the clinical value of serum calcium detection for disease diagnosis.Method：60 children with pneumonia and bone tumers were randomly selected as observation group and 60 patients with pneumonia andnon bone cancer patients as control group，and 60 patients with pneumonia and rickets as control group，testing its phosphatase and serum calcium，respectively.Test results were compared with those of the disease. Result：The observation group of serum calcium phosphorus concentration was lower than that of the control group，the serum calcium and alkaline phosphatase positive detection rate was higher than that of the control group.Conclusion：In the detection of disease，alkali esterase and serum calcium detection rate is closely related with the disease.

2015 Vol. 12　(16):　146-148 [Abstract]（ 429 ） HTML (1 KB)  PDF  (671 KB)  ( 175 )

Objective：To provide reference for the clinical application of Dragon’s blood.Method：Relevant literatures  were retrieveD，the clinical application of Dragon’s blood were summarized.Result：Dragon’s blood was mainly used in cardiovascular disease，diseases of the digestive system，diabetes and complications，skin diseases，gynaecology diseases and anorectal diseases.But listed dosage forms were only powder，capsule and tablets.Conclusion：Dragon’s blood has a wide application range，but listed dosage forms are less，it needs to strengthen the research and development.

2015 Vol. 12　(16):　154-156 [Abstract]（ 579 ） HTML (1 KB)  PDF  (661 KB)  ( 541 )