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| Study on the Correlation between Relaxin， Pelvic Floor Electrical Physiology and Female Pelvic Floor Dysfunction |
| Sun Yat-sen University Affiliated First Hospital，Zhongshan 510080，China |
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Abstract Objective： To probe into the correlation between relaxin， pelvic floor electrical physiology and female pelvic floor dysfunction，provide guidance for disease prevention. Method： 100 patients underwent hysterectomy in benign disease in gynaecology department in our hospital from May 2012 to August 2012 were selected， detected pelvic POP-Q， conventional bimanual gynecological examination in patients the day before the operation， at the same time measured pelvic floor muscle strength to clear pelvic floor function， pelvic organ prolapse， pelvic floor muscle. Result： 83 cases of postmenopausal patients measured serum relaxin H2 level was（157.4±263.9） pg/mL， 17 cases of premenopausal patients was（212.9±355.8） pg/mL， with no significant difference（ t=0.742， P=0.460）.There was no significant correlation between patients age（X） and serum relaxin H2 levels（Y）.The correlation regression equation：Y=2.987X+22.118， R2=0.006，had no significant difference（ P>0.05）， there had no significant correlation between two elements. Mild（ 1， 2 degree） for relaxin level（ 175.5±69.9） pg/mL， severe（ 3， 4） for relaxin level（ 227.6±93.4） pg/mL （comparison of two elements， t=4.023， P=0.000），the lower of the degree， the higher level of serum relaxin， suggested there was a certain correlation between serum hormone level and the degree of pelvic organ prolapse in patients. The serum H2 level had no obvious correlation with the relaxation in patients with POP and the diameters of pelvic floor muscle parameters .Conclusion： There is no significant correlation between relaxin， pelvic floor electrical physiology and pelvic floor dysfunction，so the degree of pelvic relaxation cannot be reflected completely， but they have some relationship with the degree of pelvic organ prolapse，it needs to expand the sample to confirm.
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