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| Oxidative Stress and Immune Status Impact Study on Sepsis Patients by ω-3 Polyunsaturated Fatty Acids |
| Shenzhen Second People’s Hospital， Shenzhen 518000，China |
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Abstract Objective：To explore the oxidative stress and immune status impact study on sepsis patients by ω-3polyunsaturated fatty acids.Method：Patients were randomly divided into observation group and control group， 30 cases in each group.Two groups of patients were accepted nutrients such as nitrogen， such as heat all-in-one parenteral nutrition support and the corresponding conventional treatment， continuous for 7 d.Which controls provided by the long chain fatty milk 20%， observation group by omega-3 polyunsaturated fatty acid + 20% long chain fatty milk.Before and after treatment oxidative stress response and immune function changes of the related indexes were compared of the two groups， and make analysis summary.Result：The observation group in the eighth day after the treatment of inflammation and immune indexes improved than the control group significantly（ P<0.05）， oxygen stress index， plasma lipid peroxides LOP， serum MDA declined significantly，serum glutathione GSH was increased after treatment（ P<0.05）， oxidative stress response to effective control.Conclusion：Omega-3 PUFAs can improve the immune function of patients with sepsis， reduce inflammation， effective control of oxidative stress reaction.
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