Abstract Objective:To observe the microinflammatory,volume,nutritional indicators with different peritoneal transport type in CAPD patients before peritonitis occurs,and analyze the possible relationship between peritonitis,microinflammation and peritoneal transport type.Method:Patients proceeded the peritoneal equilibration test between first month and third month after accepting the peritoneal dialysis tube placement surgery.Group A( Non-fast transport) and group B( fast transport) were divided considered by the test result.The patients were detected lab indicators from the third peritoneal dialysis month,including hsCRP,IL-6,SBP,DBP,pro-BNP,PA,ALB,and then the same detection was conducted once every 2-4 months,which has been completed 4 times observe termination was event of peritonitis.Correlation analysis was done after the observation.Result:Group B showed a higher microinflammation,average blood pressure and pro-BNP level than group A,meanwhile the above indicators in patients with peritonitis were also higher than patients without peritonitis in peritoneal dialysisstage( P<0.05).The blood albumin,prealbumin both presented a lower level in group B than in group A,and in peritonitis patients than in non-peritonitis patients,with the time prolonged during the early dialysis stage,both in the observation group B presented descend trend significantly( P<0.05).IL-6 and hsCRP were correlated with PA and ALB negatively( P<0.05),and were correlated with pro-BNP as well as peritonitis positively in patients with fast peritoneal transport( P<0.05).Conclusion:The microinflammatory status is more serious in patients with peritoneal fast transport than those are not,which is correlated with volume overload and poor nutrition status,the three factors plays an important role in the development of the fast
peritoneal transport patients with peritonitis by interact causally.
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