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| Clinical Efficacy Analysis of Long-Term Use of Finasteride in Benign Prostatic Hyperplasia |
| Qishi Hospital of Dongguan City，Dongguan 523500，China |
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Abstract Objective：To investigate clinical efficacy analysis of long-term use of finasteride in benign prostatic hyperplasia.Method：80 patients with BPH，who were diagnosed from June 2007 to August 2009 in our hospital were chosen.Every patient was obtained 5 mg finasteride per day，and was followed up at least 5 years.After and before control was chosen，and frequencies of nocturia，prostate volume in finger exam and B ultrasound，serum creatine，complete blood count，Ru，Qmax，PSA，adjusted PSA and IPSS were noted.Result：Serious side effects of treatment was not observed.Compared to pretreatment，frequencies of nocturia，Qmax，IPSS increased，prostate volume in B ultrasound，platelet，haemoglobin，Ru decreased，whose differences were significant（P<0.05）. Conclusion：Finasteride can decrease prostate volume，improve urodynamics functions and increase IPSS，serious side effects in long-term use do not occur.So it is worthy of clinical promotion.
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