|
|
|
| The Clinical Significance of BNP and the NT-proBNP in the Diagnosis of Heart Failure |
| Chaoyang District People’s Hospital of Shantou City， Shantou 515100，China |
|
|
|
|
Abstract Objective：To explore the change of blood levels and clinical significance of the b-type brain natriuretic peptide（ BNP） and the amino terminal b-type brain natriuretic peptide（ NT - proBNP） in patients with heart failure（ hereinafter referred to as the heart failure）. Method： 82 cases of heart failure patients who were admitted in our hospital from July 2013 to June 2014 were retrospective analyzed（ heart failure group）. New York heart association （NYHA） standard cardiac function was used in patients with cardiac function classification and echocardiography was used to evaluate patients’ cardiac function. in the same period in the hospital， 60 cases of patients with normal cardiac function were selected as control group. All patients was drawn fasting venous blood. Two indicators，left ventricular ejection fraction（ LVEF） and level of difference in patients with different cardiac function NYHA class were analyzed.Result： The blood BNP， NT - proBNP of the heart failure group were significantly higher than that of the control group， the difference was statistically significant（ P<0.01）. In the heart failure group， heart failure increaseed with NYHA classification，BNP， NT - proBNP level increased， the two indexes difference in different levels of cardiac function had statistical significance（ P<0.01）. Two index level and cardiac function classification were significantly positive correlation， negative correlation with LVEF classification. Conclusion：BNP and NT - proBNP are heart failure diagnostic markers.They have important clinical significance to the differential diagnosis，risk stratification of different degree of heart failure and the guidance of clinical.
|
|
|
|
|
|
|
|
|
