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Abstract Objective： To explore the influence of the intermediate dialysis weight change of maintenance
hemodialysis patients and analyze correlative factor of the malnutrition. Method： 71 patients with the end-stage renal disease who requiring maintenance hemodialysis were selected. All patients were divided two groups according to the intermediate dialysis weight change. To detect the indexes respectively. The dry weight（ DW）， intermediate dialysis weight growth， the change of DW and BMI anthropometric indicators. Result： There were statistically significant of the DW，BMI， between group A and B after 12 months later. There were statistically significant differences in HB， RBC， TC， TG，
LPɑ， HCO-3， nPCR， SPKT/V， ALB， and CRP between group A and B， while there were no statistically significant differences in Ca， P， iPTH， BS， GHB. Conclusion： IDWG has advancing effect to the malnutrition of maintenance hemodialysis patients. Correlation with hypertension， hyperlipemia and chronic inflammation state could enhance malnutrition through hypertension， hyperlipemia and chronic inflammation state.
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