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| The Study of Lipid Regulating Effects of Rosuvastatin and Fluvastatin for Patients with Unstable Angina |
| The People’s Hospital of Pizhou，Pizhou 221300，China |
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Abstract Objective：To investigate the rosuvastatin and fluvastatin clinical efficacy of statin lipid-lowering effects of unstable angina.Method：98 cases were randomly divided into observation group and control group， 49 cases in each group.In the conventional treatment including nitrates， anti-platelet drugs， calcium antagonists and anti-clotting drugs on the basis of that，the control group was took fluvastatin 20 mg， orally once every night；observation group was took rosuvastatin 10 mg， orally once every night，the observation times of two groups were 8 weeks.The clinical efficacy and changes of before and after treatment of lipid and C--reactive protein（ C-response protein， CRP） concentrations in both groups were Observed.Result：The clinical improvement in symptoms of both groups，compared with the control group，the response rate was respectively 93.88% and 79.59%（P<0.05）；total cholesterol， triglycerides， LDL and CRP levels of observation group were significantly lower，the differences were statistically significant（ P<0.05）；serum highdensity lipoprotein of observation group significantly increased， the difference was statistically significant（ P<0.05）. Conclusion：Aosuvastatin and fluvastatin can improve clinical symptoms in patients with unstable angina， lipid effects obvious， and rosuvastatin are better than fluvastatin.
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