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Experimental Study of the Bulbar Conjunctiva Microcirculation and Hemorheology after Acid Burns |
The First Hospital of Hebei Medical University,Shijiazhuang 050031,China |
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Abstract Objective:To observe the changes in bulbar conjunctiva microcirculation of acid burned rabbitsduring early burning, to study the regularity and characters of its changing, and changes of hemorheology,then exploreits effect on blood viscosity.Method:The healthy adult rabbits were selected as experimental objects, and were randomlydivided into control group and burn group, duplicate the model of acid burn, when two groups after injury immediately,after injury 30 min,1 h, 2 h, the bulbar conjunctiva microcirculation were observed, blooding when two groups afterinjury immediately, after injury 8, 24, 48 h,the parameters included whole-blood viscosity(ηb), whole-blood restoreviscosity(ηr), plasma viscosity(ηp), erythrocyte sedimentation rate(ESR), K value of ESR equation(K),hematocrit(HCT), fibrinogen(FB), erythrocyte stiffen index(TK), erythrocyte aggregation index(EAI), test data
were measurement data,and were analyzed by t test.Result:Total credit value of four phases respectively compared withthe control group, there was significant difference( P<0.05). Compared the two groups ηb and ηr, and four phase atthe same shear rate, the value in burn injury group was higher than that in control group( P<0.05); compared two groupsof ηp, HCT, ESR, K, FB, EAI, TK, the values of burn group in each phase were higher than those of control group(P<0.05).Conclusion:After acid burns, bulbar conjunctiva microcirculation changes severely, affecting blood flowvelocity in the blood vessels, leading to changes in blood rheology.
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