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| Cardiovascular Autonomic Nerve Function in Patients with Primary Hypertension with Diabetes and Blood Pressure |
| Guangzhou Huadu District People’s Hospital，Guangzhou 510800，China |
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Abstract Objective：To explore the relationship between cardiac autonomic function and blood pressure circadian rhythm in diabetic hypertensive patients.Method：70 essential hypertensive patients were recruited， 35 complicate with diabetes as the experimental group（ group EH-DM） and the other 35 with normal blood glucose as the control group（ group EH）.They underwent standard cardiovascular autonomic function tests（ SCAFT） and ambulatory blood pressure monitoring（ABPM）.Result：The SCAFT score was higher in the group EH-DM than in the group EH P<0.05）.The decline of SBP at night（ΔSBP%）was lower in the group EH-DM than in the group EH（P<0.05）.The ratio of non-dipping circadian rhythm in the group EH-DM was higher than that in the group EH（ P<0.05）.The decline of SBP at night and SCAFT score appeared in an obvious negative correlation（r=-0.328，P<0.05）.Conclusion：The diabetic hypertensive patients have higher SCAFT score and higher ratio of non-dipping circadian rhythm.Blood glucose may affect blood pressure circadian rhythm through impairing cardiovascular autonomic function.
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