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Abstract Objective：To explore the method and effect of skin and soft tissue defect of thumb flap repair.Method：60 cases of skin and soft tissue defect of thumb were selected in our hospital in recent two years received as the research object， with the different treatments will be divided into the observation group， the study group and the control group three groups， 20 cases in each group， the observation group underwent free skin flap in repairing treatment， study group treated with flap repair treatment， the control group underwent pedicled repair treatment， the treatment of patients with three groups.Result：The results of this study show that the observation of patients in the treatment group the excellent and good rate was 80.0%， the treatment of patients in the study group the excellent and good rate was 75.0%， control group was treated with the excellent and good rate was 85.0%； three patients in treatment group had no significant difference compared to the excellent rate（ P>0.05）， no statistical significance.Conclusion：Skin and soft tissue defect of thumb with skin flap repair treatment should be to patients with thumb defect degree and medical level as a basis to choose the best method to repair， as far as possible to restore the function of the thumb and the appearance of the patients.
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