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| Expression and Significance of Interleukin-22 in HBV Related Liver Diseases |
| The First Affiliated Hospital of Guangxi Medical University，Nanning 530021，China |
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Abstract Objective：To explore the expression and significance of IL-22 in HBV related liver diseases.Method：Whole vein blood was obtained from healthy control（HC）（n=25）and experimental groups including thepatients with asymptomatic carrier（ASC）（n=30），chronic hepatitis B（CHB）（n=40），liver cirrhosis（LC）（n=45），hepatocellular carcinoma（HCC）（n=30）.The level of serum IL-22 were analysed by ELISA.Statistical analysis of the relevance of IL-22 levels and AFP was performed.Result：IL-22 level in the CHB group，LC group， and the HCC group were higher than that in the healthy control（ P=0.010，0.003，0.000）.IL-22 levels had no correlation with AFP.Conclusion：IL-22 may contributed to the occurrence and the development of liver fibrosis and hepatocellular carcinoma.
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| [1] |
YANG Junjie,ZHONG Yanping,MAO Jing,LIU Xinhua,LI Shan,LIU Yuanyuan,LEI Xu,LEI Feifei,LEI Yu,GUO Peng,HU Bo,LIU Zhixin,TAN Huabing. Effect of Plasma Exchange Combined with Double Plasma Molecular Adsorption System on Hepatocyte Regeneration in Hepatitis B Virus-associated Acute-on-chronic Liver Failure[J]. 中国医学创新, 2023, 20(5): 63-69. |
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