Abstract Objective：To discuss the risk factors of nosocomial infection in NICU，study its preventivestrategies， and provide scientific basis for reducing the nosocomial infection rates. Method： A statistical analysis of theinfection rate， infective sites and pathogens of nosocomial infection among 1026 cases of neonatal inpatients in our hospitalfrom January 2013 to December 2013 was performed with retrospective analysis method. Result： Among 1026 neonatesunder the surveillance， there were 23 infection cases and 26 infection times. The nosocomial infection rate was 2.24%， thecase time infection rate was 2.53%， and the daily infection rate was 2.73‰ .We found that the infection rate was relatedto the birth weight. Furthermore， the lower respiratory tract and hematological system were the predominant infectionsites， which accounted for 26.92% and 23.08%， respectively. Among all the cases， the application rate of ventilator was
2.61% ， and the incidence rate of ventilator-associated pneumonia was 22.73‰ . Conclusion：The targeted surveillanceis conducive to analyze the high-risk factors of nosocomial infection and to put forward effective prevention and controlmeasures for nosocomial infection.
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