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| Effect of Simultaneous Guided Bone Regeneration with Dental Implantation on Bone Resorption around Implants and Periodontal Status in Patients with Periodontitis |
| ZENG Sili |
| Ruijin People's Hospital, Jiangxi Province, Ruijin 342500, China |
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Abstract Objective: To investigate the effect of simultaneous guided bone regeneration (GBR) with dental implantation on bone resorption around implants and periodontal status in patients with periodontitis. Method: A total of 60 patients with periodontitis treated in Ruijin People's Hospital from October 2019 to May 2021 were divided into two groups according to the random number table method, with 30 cases in each group. The control group was treated with dental implantation, and the observation group was treated with GBR during dental implantation. The patients were followed up for 12 months. The bone resorption around implants, periodontal condition, inflammatory factor level and oral health quality of life were compared between the two groups. Result: At 6 and 12 months after operation, the mesial bone absorption [(2.05±0.27), (1.25±0.22) mm] and distal bone absorption [(2.11±0.29), (1.32±0.26) mm] in the observation group were less than [(2.68±0.34), (2.29±0.32) mm], [(2.57±0.31),(2.14±0.29) mm] in the control group, with statistical differences (P<0.05). The dental probing depth (PD)[(1.62±0.21) mm], gingival index (GI) [(0.42±0.08) points], plaque index (PLI) [(0.88±0.14) points] and gingival sulcus bleeding index (BI) [(0.82±0.13) points] in the observation group 6 months after operation were lower than [(2.09±0.35) mm, (0.65±0.12) points, (1.21±0.22) points, (1.03±0.24) points] in the control group, with statistical differences (P<0.05). The level of interleukin-6 (IL-6) [(2.28±0.43) pg/mL], C reactive protein (CRP) [(4.24±0.53) mg/L] and tumor necrosis factor-α (TNF-α) [(40.31±4.28) pg/mL] 6 months after operation in the observation group were significantly lower than [(3.34±0.58) pg/mL, (6.04±1.05) mg/L, (47.32±4.87) pg/mL] of the control group (P<0.05). The scores of oral physiological function [(5.26±1.05) points], psychological function [(8.12±1.14) points], behavioral influence [(3.25±0.41) points] and pain and discomfort [(6.34±1.08) points] in the observation group 6 months after operation were lower than [(6.87±1.12), (9.86±1.23), (4.19±0.46), (7.59±1.14) points] in the control group, with statistical differences (P<0.05). Conclusion: GBR during dental implantation can enhance the therapeutic effect of periodontitis, prevent bone absorption around the implant, reduce periodontal inflammatory reaction, improve periodontal status, and improve oral health and quality of life.
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Received: 08 October 2022
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