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| Meta-analysis of Risk Factors for Acute Myocardial Infarction in Young Adults |
| MO Jianjiao, HUANG Xiannan, LIU Yan, LIU Li, ZHOU Liufang |
| Affiliated Hospital of Youjiang Medical University for Nationalities, Baise 533000, China |
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Abstract Objective: To systematically evaluate the main risk factors of acute myocardial infarction in young adults, and to provide evidence for preventive decision-making. Method: PubMed, Embase, Web of Science, Cochrane, Library, Wanfang Data, China National Knowledge Network (CNKI), VIP, and China Biomedical Literature Database (CBM) were searched for all literatures from the date of database establishment to April 2022, comprehensively collect all case-control studies related to risk factors for acute myocardial infarction in young adults. The data were initially screened and independently extracted by two evaluators, and the methodological quality was evaluated. For the research that meets the requirements, RevMan 5.3 and Stata 14.0 statistical software are used to analyze the extracted relevant data. Result: A total of 7 case-control studies were included, including 1 061 cases in the case group and 1 627 cases in the control group. The results of meta-analysis showed that smoking [OR=2.40, 95%CI (1.84, 3.13)], family history of cardiovascular disease [OR=1.97, 95%CI (1.53, 2.55)], hyperlipidemia [OR=1.79, 95%CI (1.52, 2.12)], hypertension [OR=2.17, 95%CI (1.61, 2.92)], diabetes mellitus [OR=1.99, 95%CI (1.11, 3.56)] were associated with acute myocardial infarction in young adults. Conclusion: Smoking, family history of cardiovascular disease, hyperlipidemia, hypertension and diabetes are risk factors for acute myocardial infarction in young adults.
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Received: 15 January 2023
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