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Abstract Objective：To study the curative effect，living quality and side effect of body-gamma knife radiotherapy in treating with early-stage non-small cell lung cancer.Method：The clinical data of 58 non-small lung cancer patients who were treated with rotary body gamma knife in our hospital from October 2004 to March 2011 were retrospectively analyzed.Result：All the 58 cases completed the treatment on schedule.The recent complete remission rate of the primary lesion was 56.8%，partial remission rate was 20.7% and the stability rate was 1.7%.The overall response rate was 79.3%.The survival rates of 1，2 and 3-year after the treatment were 86.2%，75.9% and 67.2%.3 years after the treatment，there were 23 cases with neoplasm local recurrence and metastasis.19 cases died，among them，12 cases died of recurrence and metastasis and 7 cases didn’t die of neoplasm.The amount of patients with anxiety，expiratory dyspnea and cough after the treatment were less than before treatment，the differences were statistically significant（P<0.05）. The complications of radiotherapy were less，24.1%（14/58） of the patients were with radiation pneumonitis，13.7%（ 8/58）of the patients were with radiation esophagitis and 15.5%（9/58） of the patients were with stage Ⅰ leucopenia.Conclusion：With good sort-term effects and survival rate，less radiotherapy complications，body-gamma knife is an useful and safety nonsurgical treatment in treating with early-stage non-small cell lung cancer.
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